Thumbnail of Levels of transgene expression in transgenic (Tg) mice expressing deer or elk cellular prion protein (PrPC). Representative Western blot analysis of PrPC expression from different total protein loads in brain extracts from Tg mice Tg(CerPrP)1536+/–, Tg(CerPrP-E226)5029+/–, and Tg(CerPrP-E226)5037+/– compared with wild type and Prnp0/0 mice (knock-out mice for PrP gene).