HIF-1α induces cell growth mediated by the UCA1/PTEN/AKT signaling pathway. (A) HIF-1α-induced promotion of cell growth was abrogated by pPTEN or AKT inhibitor wortmannin in the MG-63 and U-2OS cells. (B) Western blot assays showed that HIF-1α-induced upregulation of Ki-67 was almost abolished by p-PTEN and wortmannin in the MG-63 and U-2OS cells. *P