The 3RT-apoB antibody reduces Tau accumulation in the brain. (a) Representative, immunoblot analysis of brain homogenates from non-tg and 3RTau tg mice treated with LV-3RT, LV-3RT-apoB or LV-control showing levels of Tau proteins: 3RTau, p-Tau (PHF1), and total Tau (T-Tau) as well as the level of the 3RT scFv protein (V5) with ß-actin as a loading control. Image analysis of pixels of (b) V5, (c) 3RTau, (d) PHF1, and (e) T-Tau immunoreactivity analyzed as ratio to ß-actin signal. * indicates statistical significance p