enhancement of mammary tumor formation in mice by a cytostatic drug melphalan melphalan lphenylalanine mustard a cytostatic drug used in treatment of human breast cancer was injected into mice bearing preneoplastic hyperplastic alveolar nodule mammary outgrowth line d2 melphalan doses of either 25 or 50 mgkg markedly enhanced tumor formation in its mammary nodule outgrowth line samples of nodule outgrowths in untreated mice produced 13 tumors by 9 months after transplantation whereas nodule outgrowths in melphalantreated mice produced 57 and 85 mammary tumors in the lower and higher dose groups respectively nuclear magnetic resonance a review of principles and applications in medicine and chiropractic nuclear magnetic resonance nmr has in principle been known since 1946 and has found many applications in the fields of physics and chemistry however although it has only been in recent years that it has found potential use in various fields of medicine it is rapidly proceeding from research and development to the practical clinical stage this paper seeks to provide a brief review of nmr principles and applications current in medicine and potential applications in the field of chiropractic