an alternative dressing material for the splitthickness skin graft donor site oxidized regenerated cellulose the splitthickness skin graft stsg donor sites have been treated with various and plenty of dressing techniques and materials an ideal stsg donor site dressing should have antibacterial hemostatic and promoting epidermal healing properties we have performed a prospective study to evaluate the effect of the oxidized regenerated cellulose on stsg donor site healing between january 2002 and january 2005 40 patients who were operated in any kind of reconstructive operations with stsg donor sites were included in the study one half of the wound was covered with oxidized regenerated cellulose and the other half of the same wound of the same patient was covered with fine mesh gauze treated with furacin nitrofurazone the patients were grouped into 2 depending on the dressing technique group i semiclosed and group ii closed the wounds were evaluated for healing time infection pain perception of the patient and final esthetic results the oxidized regenerated cellulose side of the group i was healed in a mean of 65 051 days in group ii 54 050 days range 56 days the fine mesh gauze treated with furacin in group i was healed in a mean of 99 097 days range 811 days in group ii 84 099 days range 710 days there was a statistical significance between the oxidized regenerated cellulose side and the fine mesh gauze side p 0001 in group i and group ii separately the difference between group i and group ii was statistically significant in the oxidized regenerated cellulose side p 0001 and the difference between group i and group ii was statistically significant in the fine mesh gauze side p 0005 the antibacterial hemostatic and absorbable property of the oxidized regenerated cellulose could ensure the utilization as an alternative stsg donor site dressing especially because the positive influence over the wound healing was proven