clinical observation on effect of compound ebei ointment in treating plaque psoriasis objective to observe the efficacy oand safety of compound ebei ointment cebo in treating plaque psoriasismethods adopting blockrandomized open positive western medicine and placebo parallel group controlled method a total of 120 enrolled patients were administered orally with saoxuan pill and randomized into three groups respectively treated with external application of cebo daivonex or vehicle control twice a day for 4 weeks the changes of erythema infiltration scaly eruption pruritus and the area of lesion were evaluated the safety and the initiating time of symptom improvement itsi were observed as wellresults observation on local lesion showed that the scores of erythema infiltration scaly eruption pruritus were significantly improved in difference between the cebo group and the daivonex group p 001 but in the placebo control group significant improvement was only shown in scaly eruption scores p 001 so the improvement in skin lesion in the placebo group was significantly inferior to that in the other two groups p 001 the itsi of pruritus was shorter in cebo group than that in the daivonex group and the placebo group p 001 but that of other symptoms showed insignificant difference between the cebo group and the daivonex group as for comparing in itsi of erythema infiltration scaly eruption and pruritus it was significantly shorter in the cebo group and daivonex group than that in the placebo group respectively p 001 the occurrence of adverse events in the cebo group had insignificant difference to that in the daivonex group but the recurrence rate in the former was significantly lower than that in the latter p 005conclusion cebo can effectively improve the symptoms of skin lesion in patients with plaque psoriasis the clinical efficacy is not inferior to that of positive western medicine