the effect of an intensive patients education program on anxiety depression and patient global assessment in diabetic foot ulcer patients with wagner grade 12 a randomized controlled study this study aimed to synthetically evaluate the impact of intensive patients education program iep on anxiety depression and patient global assessment pga in diabetic foot ulcer dfu patientsone hundred eighty dfu patients with wagner grade 1 and wagner grade 2 were consecutively recruited in this randomized controlled study and randomly assigned to iep group n90 or control group n90 as 11 ratio in the iep group patients received the iep and usual care and patients in the control group received usual care only iep included educating patients and their family members supervising patients harmful habits and diets psychological care for the patients and establishing a patientphysiciannurse wechat group hospital anxiety and depression scaleanxietydepression hadsad and zung selfrating anxietydepression scale sassds were applied to assess anxietydepression at m0m3 pga score was also assessed at m0m3for anxiety assessment iep group presented decreased hadsasas scores at m2m3 and increased hadsasas score changes m3m0 compared to control group for depression assessment iep group displayed reduced hadsdsds scores at m2m3 and raised sds score change m3m0 compared to control group moreover iep group exhibited reduced pga score at m1m2m3 and elevated pga score change m3m0 compared to control group further subgroup analyses disclosed that iep reduced hadsasashadsdpga scores at m3 and elevated these score changes m3m0 in patients with wagener grade 2 but not wagener grade 1iep ameliorates anxiety depression and pga in dfu patients with wagner grade 2 but not wagner grade 1