the relationship of personality traits and entrepreneurship tendencies with career adaptability of nursing students purpose this study was performed to reveal the relationship of nursing students personality traits and entrepreneurship tendency with career adaptabilitymethod this descriptive and correlational studys sample consisted of the junior and senior students in the nursing faculty of a state university in istanbul n265 the data was collected using the student information questionnaire career adaptabilities scale ten item personality inventory and scale of university students entrepreneurship descriptive tests and pearsons correlation analysis were used for data analysis multiple linear regression analysis was used to determine the variables that affect the career adaptability of nursing studentsresults the mean points on the personality inventory subdimensions of nursing students were highest in conscientiousness 572 sd 129 and lowest in emotional stability 446 sd 133 the mean on the scale of university students entrepreneurship was 1352 sd 1950 and on the career adaptabilities scale was 787 sd 905 the significant relationship between the personality traits entrepreneurship tendency and career adaptability scores of the students was weak and moderate the regression model used to determine the variables that affect the career adaptability of nursing students was significant of the variables in the model entrepreneurship tendency and being a fourthyear student significantly influenced the total score on career adaptabilityconclusion the results showed a correlation between personality traits and career adaptability in addition there is a positive correlation between entrepreneurship tendency and career adaptability the students with high entrepreneurship tendencies have better career adaptability the results suggest that nursing education should improve entrepreneurial and intrapreneurial traits by considering the personality traits of students in order to ensure their adaptation to the nursing profession