clinical outcomes of wavefrontguided laser in situ keratomileusis 6month followup purpose to evaluate the clinical outcomes 6 months after wavefrontguided laser in situ keratomileusis lasik for myopia in japansetting department of ophthalmology sanno hospital tokyo japanmethods this prospective study comprised 22 eyes of 12 patients treated with wavefrontguided lasik who were available for evaluation at 6 months the mean patient age was 312 years 84 sd range 23 to 50 years and the mean preoperative spherical equivalent refraction was 730 272 diopters d range 275 to 1188 d in all cases preoperative wavefront analysis was performed with a hartmannshack aberrometer and the technolas 217z flyingspot excimer laser system bausch lomb was used with 10 mm and 20 mm spot sizes and an active eye tracker with a 120 hz tracking rate the clinical outcomes of wavefrontguided lasik were evaluated in terms of safety efficacy predictability stability complications and preoperative and postoperative aberrationsresults at 6 months 10 eyes had no change in best spectaclecorrect visual acuity and 10 gained 1 or more lines the safety index was 111 and the efficacy index 082 slight undercorrections were observed in highly myopic eyes in all eyes the postoperative refraction tended slightly toward myopia for 3 months and stabilized after that no complication such as epithelial ingrowth diffuse lamellar keratitis or infection was observed comparison of the preoperative and postoperative aberrations showed that 2ndorder aberrations decreased and higherorder aberrations increased in the 3rd order aberrations increased in the highmyopia group 60 d or worse and decreased in the low to moderatemyopia group better than 60 dconclusion wavefrontguided lasik was a good option for refractive surgery although a longer followup in a larger study is required