enzymatic digestion of liposomebound polysaccharides evidence of bridging mechanism laminarin a watersoluble polysaccharide is known to induce aggregation and fusion of liposomes using laminarin specific lysing enzymes for multilamellar liposomes their aggregation was found to be fully reversible in contrast to small unilamellar liposomes for which irreversible fusion is the main process moreover our results indicate that these processes are probably mediated by the formation of polysaccharide crossbridges between adjacent liposomes role of mri in patient selection for crt magnetic resonance imaging has great potential for aiding in the selection of patients who will respond to crt mri is the only imaging tool that can simultaneously assess mechanical dyssynchrony determine the amount and location of myocardial scar tissue and map the location of cardiac venous anatomythree important factors in predicting a patients response to crt the goal of this manuscript is to review the mri methods that can be used in the selection of patients for crt