placentarelated complications in women carrying a foetus with congenital heart disease introduction recent studies pointed to an intrinsically angiogenic imbalance in chd in the maternal and foetal circulation suggestive of impaired placentationobjectives to assess whether pregnant women with a chd foetus are at greater risk of placentarelated complicationsmethods perinatal results of women with a cdh foetus were compared with those of a nonselected population followed up at our centre multiple pregnancies and chromosomal abnormalities were excluded from the analysisresults about 279 pregnancies with chd foetuses were included mothers were classified in three groups according to the foetal cardiac defect 104 373 atrioventricular defect 102 365 conotruncal anomalies and 73 262 leftventricular outflow tract obstruction a significantly higher incidence of preeclampsia was observed in the chd group compared with the normal population 57 versus 12 p00001 or 596 95 ci 3191054 about 97 of foetuses with chd had3rd birth weight percentile compared with 3 for the normal population or 332 95 ci 239456 a higher incidence of stillbirth was also observed in the chd group compared with the normal population 25 versus 04 or 945 95 ci 335233conclusions women carrying a foetus with chd have a high risk of preeclampsia and intrauterine growth restriction the relationship between chd and placentarelated complications could be an encouraging topic for future research