between visit variability of thermal imaging of feet in people attending podiatric clinics with diabetic neuropathy at high risk of developing foot ulcers objective people with diabetic neuropathy who have previously ulcerated are at high risk of reulceration they should regularly attend podiatry clinics for surveillance and routine protective podiatric treatment it has been suggested that inflammation prior to skin breakdown shows up as a hotspot on a thermal image even in the absence of clinical signs the aim of this study is to quantify interpatient and intrapatient thermal variations presented by diabetic feet at high risk of ulcerationapproach whole foot and spot temperatures were recorded for 96 patients who attended two successive podiatry appointments without ulceration 28 28 31 days apart median interquartile range this was a part of a longer study into whether thermal imaging in clinic can reduce the rate of reulcerationmain results the variation in spot temperature rightleft differences for single patients between visits was comparable to the variation observed between patients 08 03 15 c compared with 09 04 17 c similarly whole foot temperature variation for a single patient between visits was comparable to the variation observed between patients 06 02 11 c compared with 08 02 13 csignificance thresholds which depend on thermal differences from visit to visit are unlikely to have sufficient specificity to effectively target treatment designed to prevent the development of foot ulcers