autologous plateletrich plasma versus conventional therapy for the treatment of chronic venous leg ulcers a comparative study background chronic venous leg ulcers drastically reduce the quality of life of affected patients there is heightened interest in autologous plateletrich plasma prp as one of the promising therapies for leg ulcersaim our aim was to compare the clinical efficacy of prp in the management of chronic venous leg ulcers vs conventional treatmentpatientsmethods in total 40 patients with chronic venous leg ulcers were included in the study twenty patients were treated with autologous prp weekly for 6 weeks group a and 20 patients were treated with conventional treatment compression and dressing for 6 weeks group b treatment results were calculated by percentage of improvement in area of the ulcerresults compared to conventional therapy a highly significant improvement in the ulcer size was observed postprp therapy pvalue 0001 the mean change in the area of the ulcer postprp and conventional therapy was 492 1194 cm and 013 027 cm respectively while the mean percentage improvement in the area of the ulcer postprp and conventional therapy was 676 366 and 1367 2806 respectively subjective improvement in pain associated with the ulcer was noted by all patientsconclusions plateletrich plasma is a safe nonsurgical procedure for treating chronic venous leg ulcers additional studies with larger sample size and longer followup periods are required to confirm or refute our findings