fatal neonatal myocarditis caused by a recombinant human enterovirusb variant we report a case of fatal myocarditis in a newborn infant who was infected with a human enterovirus detected by throat culture and rtpcr for viral rna in plasma whole genome sequence analysis revealed the virus to be a genomic chimera that likely arose from recombination between coxsackievirus b3 and two recently identified enteroviruses ev 86 and ev97 identification of a new p1 residue mutation 444argser in a dysfunctional c1 inhibitor protein contained in a type ii hereditary angioedema plasma a new reactivecentre p1 residue mutation 444argser has been identified in a dysfunctional c1 inhibitor protein c1 inhibitorba contained in a type ii hereditary angioedema plasma this substitution is compatible with a point mutation of the 444arg codon cgcagc and represents the first nonhistidine noncysteine p1 residue mutant described for c1 inhibitor