preliminary study of the antioxidant properties of flowers and roots of pyrostegia venusta ker gawl miers background free radical stress leads to tissue injury and can eventually to arthritis atherosclerosis diabetes mellitus neurodegenerative diseases and carcinogenesis several studies are ongoing worldwide to find natural antioxidants of plant origin we assessed the invitro antioxidant activities and screened the phytochemical constituents of methanolic extracts of pyrostegia venusta ker gawl miersmethods we evaluated the antioxidant potential and phytochemical constituents of p venusta using 11diphenyl2picrylhydrazyl dpph 2 2azinobis3ethylbenzothiazoline6sulfonic acid abts and ferric reducing antioxidant power frap assays gas chromatographymass spectroscopy gcms studies were also undertaken to assess the phytochemical composition of the flower extractsresults phytochemical analyses revealed the presence of terpenoids alkaloids tannins steroids and saponins the reducing ability of both extracts was in the range in m feiig of 11249304698 compared with butylated hydroxytoluene bht 6356 262 catechin 97202 072 m and quercetin 320827 3129 a significant inhibitory effect of extracts of flowers ic50 0018 069 mgml and roots ic50 0026 094 mgml on abts free radicals was detected the antioxidant activity of the extracts of flowers 95 and roots 94 on dpph radicals was comparable with that of ascorbic acid 989 and bht 976 gcms study revealed the presence of myoinositol hexadecanoic acid linoleic acid palmitic acid and oleic acid in the flower extractsconclusion these data suggest that p venusta is a natural source of antioxidants the extracts of flowers and roots of p venusta contain significant amounts of phytochemicals with antioxidative properties and could serve as inhibitors or scavengers of free radicals p venusta could be exploited as a potential source for plantbased pharmaceutical products these results could form a sound basis for further investigation in the potential discovery of new natural bioactive compounds