sustained ventricular tachycardia in postinfarct ischemic heart disease spontaneous polymorphism clinical therapeutic and prognostic aspects unlabelled spontaneous polymorphism sp is present when at least two episodes of sustained ventricular tachycardia svt occur spontaneously in the same patient pt with different bundle branch block pattern or with shifting of qrs axis by greater than or equal to 90 in the various episodes we undertook this study in order to investigate the clinical significance of sp in svt as well as therapeutic and prognostic implications material and methods from our global pts populations we chose those with svt in chronic ischemic heart disease cihd with previous myocardial infarction pmi they had to be already studied by electrophysiologic technique ees the pts were divided into two groups gr gr i 13 sp pts 12 m 1 f mean age 575 13 mean followup 192 11 months gr ii 15 no sp pts 14 m 1 f mean age 60 10 mean followup 99 13 monthsresults the two gr are comparable in terms of symptoms exercise tolerance infarct site intraventricular conduction disturbances 615 and 666 respectively ventricular wells kinetics 384 and 266 respectively and time interval between acute myocardial infarction the first episode of svt 758 602 and 827 657 years respectively 8 of the 10 alive gr i pts have been treated with amiodarone a 28004200 mgwk all 9 alive gr ii pts are on a 14004200 mgwk a serum level in 7 gr i pts was 17 065 mcgml and 161 067 in 5 gr ii pts 313 gr i pts died 2 for sudden death 153 615 gr ii pts died 4 suffered sudden death 266abstract truncated at 250 words