the immunogenicity of a modified intradermal preexposure rabies vaccination schedulea case series of 420 travelers background current australian recommendations for rabies preexposure vaccination involve the use of cellculturebased rabies vaccines which are administered via intramuscular im or intradermal id routes id vaccination is more affordable for travelers but is only recommended if there is sufficient time to perform serology 2 to 3 weeks postvaccination and confirm immunity prior to travel we report the immunogenicity of a modified id schedule that can be completed in less time than the standard id schedule and allow more travelers to be vaccinated prior to departuremethods travelers were offered a modified schedule if they were unable to afford standard im vaccinations and did not have time to complete a standard id course the modified schedule consisted of two id injections of 01 ml of human diploid cell rabies vaccine administered on days 0 and 7 and serology was performed to determine immune status at a time between day 21 and 28results a total of 420 travelers aged between 10 and 65 years were vaccinated using the modified id course the overall seroconversion rate was 945 with 397 travelers developing antibody levels of 05 iuml when tested at approximately 21 days postvaccinationconclusion the modified id schedule used in this case series was highly effective had similar immunogenicity to the standard id schedule and should be considered in travelers who are unable to complete standard im or standard id courses of rabies vaccines