medical treatment predicts mortality after hip fracture background the mortality after hip fracture has remained high and stable the past 50 years despite improved surgical treatment the aim of this study was to identify medications and medical factors associated with mortality after hip fracturemethods this is a prospective observational study with median observation time of 21 months three hundred and sixtyfour patients mean age 834 years and 758 women were enrolled information on comorbidity medications surgery and clinical findings were collected at the time of fracture information on cause and time of death was obtained from the norwegian cause of death registerresults six risk factors and one protective factor were identified by cox proportional hazards model adjusted for propensity score the use of diuretics adjusted hazard ratio hr 403 95 confidence interval ci 213764 history of coronary heart disease chd hr 261 ci 137498 male sex hr 232 ci 127424 barthel index 100 on admission hr 247 ci 118514 body mass index or 20 hr 194 ci 113334 and the use of statins hr 023 ci 008068 patients using diuretics had increased risk of death from all causes including death from chd chronic obstructive pulmonary disease and falls or other accidentsconclusions the use of diuretics is the strongest predictor of mortality followed by chd at the time of fracture whereas the use of statins is associated with improved survival future research is needed to evaluate whether improved diagnosis and management of chd and congestive heart failure among hip fracture patients would improve survival