an unusual alkaline phosphatase isoenzyme in a patient with concomitant marked elevation of acid phosphatase without clinical evidence of prostatic carcinoma an 81yearold male with congestive heart failure and prostatic hypertrophy was found to have markedly elevated serum acid phosphatase ec 3132 and moderately elevated serum alkaline phosphatase ec 3131 alkaline phosphatase isoenzyme analysis was performed to determine the organ source of the enzyme there was an unsual slowmigrating alkaline phosphatase isoenzyme band in the serum of this patient suggestive of hepatic origin by a variety of biochemical tests psychopathology of protracted endogenous depressions a clinicopsychopathological study of 85 patients with protracted endogenous depressions permitted to distinguish 7 main syndromological types melancholic adynamic dysphoric anesthetical anxious cenesthohypochondriacal and a complex type of depressive disorders with hallucinatory delusional and catatonic disturbances the first 5 types were characterized by syndromological simplicity and could be qualified as monomorphic the latter 2 types of depressions had a complex structure with profound positive disorders and pronounced polymorphism which in some cases had a clinical picture of a major syndrome