barriers to participation in industrysponsored clinical trials in pediatric type 2 diabetes background the rapid emergence of type 2 diabetes t2d in the pediatric population has left pediatric endocrinologists with limited artillery in terms of management while multiple medications are available for adults food and drug administration fdaapproved medications in children are limited to only metformin and insulin additional treatment options require randomized controlled trials yet heretofore several barriers at the participant and institutional level have impeded these studies from proceeding in children and adolescents identification of the most challenging obstacles that pediatric endocrinologists experience in participating in industrysponsored t2d trials may facilitate development of feasible platforms for future studiesmaterials and methods we conducted an anonymous online survey consisting of 31 questions that assessed potential barriers to industrysponsored clinical trials in pediatric patients with t2d the survey was sent to members of the pediatric endocrine society pes and members conducted the survey between october and november of 2014 as part of the survey respondents rated the significance of several possible barriers to participation in industrysponsored t2d studiesresults we received a total of 207 responses from members of pes baseline demographics showed that 50 of represented institutions care for 50 or fewer t2d patients age 18 years and younger 70 of institutions diagnose 20 or fewer new t2d cases per year and 3 racial groups predominated african american hispanic and caucasian a total of 70 of responders have a research infrastructure to participate in clinical trials but only half have dedicated research nurses protocol restrictions on participant recruitment due to current glycemic control or medication use as well as frequent visit schedules were reported to be major obstacles in addition the financial support provided to centers to carry out the studies is insufficientconclusions efforts must be made to ease the burden of research participation on both pediatric t2d patients as well as pediatric endocrinologists