precision study on capillary electrophoresis methods for metacycline a ce method for metacycline mtc determination was investigated in an interlaboratory experiment many problems were encountered in this study most of which were related to the transfer of the method to different ce equipment the reported problems could be classified into different categories problems related to the precision to the parameters in the protocol and to the mtc peak shape as the peak shape problem was partially responsible for the poor precision a new ce method was developed in order to obtain a good mtc peak shape on all equipment the precision of this new method for mtc determination was examined in an intermediate precision study where the influence of the factors time and equipment was investigated although the new method could be transferred to different instruments the precision remained poor mainly due to the contributions of the betweenreplicate and the betweeninjection variances