assessment of donor steatosis in liver transplantation is it possible without liver biopsy background macrovesicular steatosis of the liver is associated with early dysfunction or poor function of the graft after transplantation however it can be quantified accurately only through a liver biopsy that sometimes may not be available and whose result is anyway known when the recipient has already been selected it would therefore be helpful to be able to predict the degree of steatosis on the basis of noninvasive readily available variablesmethods data from 374 deceased liver donors from whom a liver biopsy had been taken were analyzed with the receiver operating characteristic area area under the curve auc to identify variables that could predict the degree of macrovesicular steatosis classified as absent to mild 030 and moderate to severe 30results steatosis was associated significantly with donor age increased body mass index bmi presence of type ii diabetes ultrasonographic features heavy alcohol consumption transaminases aspartateaminotransferase and alanineaminotransferase alt gammaglutamyltranspeptidase and glucose blood levels the combination of bmi elevation of alt presence of type ii diabetes history of heavy alcohol consumption and ultrasonography signs of steatosis could identify steatosis 30 accurately with an auc of 086 95 ci 081091conclusion fatty infiltration in liver donors can be estimated based on clinical and biochemical parameters