lowtemperature synthesis of hierarchical structures of copper oxide and their superior biological activity in this work the authors report a facile lowtemperature wetchemical route to prepare morphologytailored hierarchical structures hs of copper oxide the preparation of copper oxide collides was carried out using varying concentrations of copper acetate and a reducing agent at a constant temperature of 50c the prepared hs of cuo were characterised by powdered xrays diffraction that indicates phase pure having monoclinic structures the morphology was further confirmed by fieldemission scanning electron microscope it reveals a difference in shape and size of copper oxide hs by changing the concentration of reactants in order to evaluate the effect of h2o2 on cuo nps the prepared cuo are modified by treatment with h2o2 in general trend cuoh2o2 collide showed enhanced protein kinase inhibition antibacterial maximum zone 1634 mm against staphylococcus aureus and antifungal activities in comparison to unmodified cuo collides these results reveal that cuo hs exhibit antimicrobial properties and can be used as a potential candidate in pharmaceutical industries