wilson disease findings at mr imaging and ct of the brain with clinical correlation purpose to describe the spectrum of brain abnormalities in wilson disease hepatolenticular degeneration as depicted at magnetic resonance mr imaging and computed tomography ct and to relate these findings to neurologic and hepatologic abnormalitiesmaterials and methods fifty patients with wilson disease participated in the crosssectional study patients underwent cerebral mr imaging n 49 ct n 44 abdominal duplex ultrasound us n 46 and neurologic examination n 50 within a week relative risk and the fisher exact test were used for statistical analysisresults supratentorial and infratentorial abnormalities in the gray and white matter were found in the pyramidal and extrapyramidal system in wilson disease an abnormal striatum depicted on mr images correlated with pseudoparkinsonian signs an abnormal dentatothalamic tract correlated with cerebellar signs and an abnormal pontocerebellar tract correlated with pseudoparkinsonian signs the presence of portosystemic shunt was strongly associated with abnormality of the globus pallidusconclusion mr imaging findings were of some use in the clinical treatment of patients with wilson disease