dynamics of antimllerian hormone during controlled ovarian stimulation aim to evaluate the dynamics of antimllerian hormone amh during controlled ovarian stimulation coh and to correlate changes in amh to age estradiol e2 levels and the presence of polycystic ovary syndrome pcosmethods data were retrospectively collected from women presenting for coh in the outpatient clinic of a university hospital between january and july 2011 concentrations of amh and e2 during coh with gonadotropins for in vitro fertilization ivf n68 and clomiphene or lowdose gonadotropin stimulation cycles n27 for intrauterine insemination were evaluated percentage change in amh and e2 from prestimulation values was calculated dynamics of hormonal changes were analyzed using nonparametric tests correlations between changes in amh and e2 were analyzed with spearman correlationresults during ivf stimulation amh declined steadily from prestimulation values no significant change in amh dynamics was observed during clomiphene or lowdose stimulation cycles percentage decline in amh during ivf stimulation correlated with rise in e2 at all time pointsconclusions the observed phenomena contribute to an improved understanding of amh expression and its role in the follicular development our data support the concept that amh is produced by secondary preantral and small antral follicles in the early part of stimulation and declines as these follicles are recruited into dominant growing follicles