recannulation of distal radial artery for staged procedure after successful primary percutaneous coronary intervention there are limited data regarding the snuffbox approach our experience highlights the feasibility of snuffbox approach as the access route for primary pci and recannulation of distal radial artery for staged pci toxicity to topical dimethyl sulfoxide dmso when used as an extravasation antidote dmso is a dipolar aprotic hygroscopic solvent for which a large number of pharmacologic properties have been claimed topical dmso is considered an effective and safe antidote to be used with topical cooling after extravasations of vesicant drugs a case of toxicity after its use as an antidote is described furthermore the increasing importance of dmso pharmacology as its use in haematologic patients is spreading is reviewed