fetal echogenic cardiac foci prospective postnatal electrocardiographic followup objective to determine postnatal electrocardiographic abnormalities in fetuses with echogenic cardiac foci ecf and no congenital heart disease chdstudy design a total of 41 fetuses with ecf and no chd were prospectively followed after birth with serial echocardiograms electrocardiogram ecg and 24h ecg holter the primary outcome was presence of significant abnormalities in the ecg or holterresult ecf diagnosed at a mean sd of 256 46 weeks gestation were located in the ventricles and in the atria in 39 951 and 2 fetuses 49 respectively postnatal followup was for 81 46 months range 1 to 24 none of the infants had any clinically significant abnormality in the ecg or holter ecf resolved in 10 infants 243 by 24 months of age there was no difference between infants with resolved or persistent ecf in various ecg or holter measurements comparedconclusion fetuses with ecf and no chd have no significant postnatal electrocardiographic abnormalities irrespective of ecf persistence or resolution