treatment of benign prostatic hyperplasia by longbishu capsule combined doxazosin mesylate tablet objective to observe the efficacy and safety of longbishu capsule lbs com bined doxazosin mesylate tablet dmt in treating benign prostatic hyperplasia bph methods total ly 360 bph with shen deficiency blood stasis syndrome sdbss were randomly assigned to group a b and c 120 cases in each group patients in group a took lbs placebos combined dmt those in group b took lbs combined dmt those in group c took lbs combined dmt placebos the dose for lbs was 3 pills each time 0 3 gpill twice per day the dose of dmt was 1 tablet each time 2 mgtablet once per day the therapeutic course for all was 12 months a total of 113 cases in group a were recruited in fas analysis 115 cases in group b and 116 cases in group c main efficacy indicators international prostate symptom score ipss maximum urinary flow rate qmax quality of life qol and sec ondary efficacy indicators postvoid residual urine volume pvr and prostate volume pv symptoms scores of chinese medicine cm i were observed in each group the efficacy was analyzed in the three groups by taking average age of subjects 66 years as the hierarchy factor 50 age 66 and 0 05 there was no statistical difference in clinical efficacy among posttreatment groups p 0 05 the efficacy in subjects more than 66 years old of group b was superior to that of group a and c with statistical difference p 0 05 conclusions lbs dmt or lbs combined dmt was safe and effective for treating bph lbs combined dmt was suit able for patients complicated with abnormal pvr or aged over 66 years