a new strategy to construct a cccf3 subunit via cubrcatalyzed domino reaction of homopropargyl amines an efficient synthesis of trifluoromethyl containing building blocks 4trifluoromethyl23dihydropyrroliums a new strategy for the construction of a cccf3 subunit has been developed via cubrcatalyzed domino cyclizationtrifluoromethylation of homopropargyl amines with umemotos reagent 4trifluoromethyl23dihydropyrroliums were produced in high yields the usefulness of these products has been demonstrated by the transformation of them into various other trifluoromethylated molecules application of synthetic materials for prophylaxis of adhesion disease in 5593 of the patients after laparotomy performance the pathological adhesion process is observed the local reactions of peritoneum its blood supply disturbance infection presence as well as systemic disorders biochemical genetic etc are pathogenetically important causes of this disease there is no a secure method of postoperative adhesion process prophylaxis the comparative analysis of actual methods for prophylaxis of pathological adhesions formation served as a background for proposal of the method which makes possible to escape the adhesion disease recurrence due to pathogenetic correction conduction using modern barrier materials