infant salt preference and mothers morning sickness evidence for an association between early pregnancy sickness and offspring salt nacl preference has been obtained from studying offspring as young adults to determine whether effects on nacl preference are expressed in infancy the present study examined 16weekold infants whose mothers reported either little or no vomiting n 15 or frequent moderate to severe vomiting n 14 during the first 14 weeks of their pregnancy the infants oralmotor facial reactions to each solution and their relative intakes of distilled water and 01m and 02m nacl were used as measures of preference infants of mothers who reported no or mild symptoms had a significantly lower relative intake of salt solutions than infants whose mothers reported moderate to severe symptoms p 001 the former infants also showed a greater number of aversive facial responses when given 02m nacl p 005 taken together these findings support the hypothesis that maternal dehydration induced by moderate to severe vomiting during pregnancy can lead to enhanced salt preference in offspring they also provide a potential explanation for some of the variability encountered when human infants are tested for their salt preference