gorlingoltz syndrome background gorlingoltz syndrome is an autosomal dominant inherited disorder characterized by a predisposition to various cancers clinicopathological findings of syndrome are very diverse and many symptoms begin to manifest in a certain period of lifecase the authors describe a case report of a man who at the age of 34 years presented to a dermatologist with multiple tumor lesions of the skin the lesions started to develop when he was 30 years old and thereafter increased in number histology revealed superficial superficialnodular and nodular basal cell carcinomas a total of 11 basal cell carcinomas were surgically removed and microscopically investigated the others were treated locally with imiquimod cream and cryotherapy in addition he was found to have multiple odontogenic keratocysts in the jaw and mandible as well as supernumerary and retinated teeth stomatologic and maxillofacial surgery interventions were performed further clinical and imaging examinations confirmed macrocephaly hypertelorism calcification of falx cerebri and abnormalities of the cervical vertebrae the spectrum of pathological findings met the diagnostic criteria of gorlingoltz syndromeconclusion although gorlingoltz syndrome is very rare in routine practice it usually represents a serious disease with multiple organ system involvement from a prognostic point of view early diagnosis with adequate therapy is critical if a diagnosis is confirmed lifetime dispensary care with interdisciplinary medical cooperation is necessary the authors would like to thank all physicians who participated in the diagnostics and therapy of the presented patient the authors declare they have no potential confl icts of interest concerning drugs products or services used in the study the editorial board declares that the manuscript met the icmje recommendation for biomedical papers submitted 30 8 2018 accepted 8 1 2019