Miller graduated from the University of California at Berkeley in 1951 with a Bachelor of Science in chemistry. He then went to the University of Chicago to do graduate work. In University of Chicago, he got registered for a PhD program. Initially, he started work with the theoretical physicist Edward Teller on synthesis of elements. During this time, Miller attended a lecture given by Harold Urey on the subject of the origin of the solar system. Urey presented the idea of organic molecules being synthesized in a early Earth atmosphere. It inspired Miller very much. However, he kept working with Teller. After a year of fruitless work with Teller, and the prospect of Teller leaving Chicago to work on the Hydrogen bomb, Miller approached to Urey in September 1952 for a fresh research project. At first, Urey was reluctant to put a graduate student on such a risky project but finally he agreed.
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