The name "chondroitin sulfate" sounds like a salt with a sulfate counter-anion. This is not the case. The sulfate is attached to the sugar with a covalent bond. Since the molecule has multiple negative charges at physiological pH, a cation is present in salts of chondroitin sulfate. Commercial preparations of chondroitin sulfate typically are the sodium salt. Barnhill et al. have suggested that all such preparations of chondroitin sulfate be referred to as "sodium chondroitin" regardless of their sulfation status.
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