> 店を休んで、電車で薬屋へ行きました

Does this sentence mean that: the person is absent/resting from the store
(that he may work at), and had caught the train to go to the pharmacy?

This is from the text book I am trying to work through.

I'd say it's the connection of this part that I'm unsure about: 店を休んで
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meaning
店を休んで、電車で薬屋へ行きました
G'day to you too.

If you were referring to work, school, etc., ～を休む would simply mean to 'take
time off from ～'. As you normally wouldn't actually close the entire school or
workplace.

In this instance, however, the use of 店 is telling. By choosing to not say
'work', rather 'the store' it likely means that they will be 'closing the
store temporarily'.

Some examples:

> 「今日は店は休みのようだ。」It appears that the store is closed today.
>
> 「私のお店は年中無休です。」My shop is open (without fixed closures) year round.
>
> A fixed closure day is 定休日 and an irregular closure day would be 休店日 (休業日）.

In other words, 'closing' a shop uses the word 休む by default.
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answer