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There have been a few times where I have come across `にする` and `をする` and I am
asking about different situations of when it is used and its meaning.

The first example is `Adjective (specifically な) + にする`:

> 私は出来るだけ静かにしていた。 I kept as quiet as possible.

  1. Does `静かにして` more literally mean "made quiet", how does it differ from `になる`?
  2. Does this syntax of `にする` work the same for i-adjectives (`面白いにする`)?

I've also been noticing more and more the grammar of `Noun + を/に する`

  1. What is the difference between using `を` and `に`?
  2. Is this grammar point used only because the noun isn't a suru-verb, for example does `勉強に/をする` not work?

My question has kind of just been dumped onto you but I feel like in order for
me to understand this grammar I need understand these things that have
confused me the most.
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question
grammar particle-に adjectives nouns
Word types + に/を + する
Adjectives are words that modify nouns, whereas adverbs are words that modify
adjectives and verbs.

By adding に to a na-adjective, you turn it into an adverb. In this way, 静かにする
can be seen as the adverb "quietly" directly modifying the verb する "to do":

> 静かにする。Literally "to do quietly", i.e. "to be quiet".

I think that this sense of "to be quiet" fits nicely in your example sentence.
Also note that 静かにする is a very common sentence so it can be thought of as a
set phrase.

However, note that you could use 静かに as an adverb to modify other verbs, too:

> 静かに寝ている。Sleeping peacefully/quietly

On the other hand, to turn an i-adjective into an adverb, you cannot attach に.
Instead, drop the い and replace it by a く. For example:

速い fast (adjective) → 速く fast (adverb), rapidly

> あの車は速く走ります。That car runs fast.
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> 私は出来るだけ静かに **して** いた。 I kept as quiet as possible.

The する, used with the continuative form (連用形) of an i-adjective or na-
adjective, or an adverbial phrase such as こう、そう etc., is an intransitive verb
meaning そのような行動や態度をとる ("to behave/act in a particular way").

明鏡国語辞典 states:

> する 〘自動詞〙  
>  ❻《様態を表す形容詞・形容動詞の連用形、「こう」「そう」など、副詞句に直接付いて》 そのような行動や態度をとる。「静かに **しろ** 」「人に優しく
> **する** 」「彼女とは常日ごろ親しく **して** いる」「言われたとおりに **する** 」「こう **すれ** ばいいでしょう」

* * *

>   1. Does 静かにして more literally mean "made quiet", how does it differ from
> になる?
>

No, 静かにする literally means "to behave/act quiet" → "to keep quiet".  
「神妙にする」 "to be docile"  
「勝手にする」「好きにする」 "to act as one pleases"  
静かになる means "to become quiet (after not being quiet)". It involves a change of
state or transition from being not quiet to being quiet.

>   2. Does this syntax of にする work the same for i-adjectives (面白いにする)?
>

You can use this する with i-adjectives, but not 面白いに. The continuative form of
i-adjectives ends with ～く. eg:  
優しい → 優しく 「人に優しくする」 "to be kind to others"  
おとなしい → おとなしく 「おとなしくする」 "to stay quiet"  
よい → よく 「友達と仲よくする」 "to get along with friends"

>   1. What is the difference between using を and に?
>

(I don't really know what you're asking but) ～をする can mean many different
things. Used with an を, the する is transitive. eg:  
勉強をする to **do** studying → study  
教師をする to **work as/play the role of** a teacher  
ネクタイをする to **wear** a tie  
etc...

And ～を‥にする means "make/turn ～ (into)‥" or "choose ～ as ‥". eg:  
牛乳をチーズにする "make milk into cheese"  
部屋をきれいにする "make a room clean"  
山田さんを議長にする "make Yamada-san a chairperson / elect Yamada-san chairperson"  
ワインをお土産にする "choose wine as a gift"  
etc...

>   2. Is this grammar point used only because the noun isn't a suru-verb, for
> example does 勉強に/をする not work?
>

Well, it's because the する has a different meaning.  
You can say "Noun+に+する" using this する, though it doesn't seem productive,
since this is the only example that I can think of:  
いい子にする _lit._ "to behave/act a good child" → "to be a good boy/girl".

勉強にする doesn't make sense.
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