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Below is an excerpt from 天声人語 Jun. 14 2010:

> 東京大の宮崎徹教授らが、体脂肪を减らすたんぱく質を見つけたという。脂肪を作る働きを抑え、ため込んだ分を **使わせる** 効果があるそうだ。

I wondered for quite some time why 使わせる instead of 使う is used here. Then I
speculate that it is an omission of the agent, or the second (二格) object:

> [ **人に** ]ため込んだ分を使わせる

But I'm not sure. I searched Reverso Context and found this similar example:

> 全ての物資をラ・ベルから運ばねばならず、 **体力を使わせる** 仕事は7月半ばに終了した。

I guess it's

> [ **私に** ]体力を使わせる

But I am still no more confident about that.

And a further question, if I am right in devising this "agent" theory. I
accept that, it is because a laborious (that is, labor-consuming, 体力を使う) task
consumes `your` strength that `you` is involved. But it seems unclear to me
how a fat-reducing protein can involve the person using this protein when it
takes effect (that is, draining excess body fat, ため込んだ分を使う).

If there's a biological reason for that I think I'm just unlucky.
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question
causation object
Implied agent of 使わせる
One type of protein itself cannot directly produce, store or consume fat.
Here, the implied agent ("causee") of 使わせる is the same as the subject of 脂肪を作る
or (脂肪を)ため込む, that is, one's body.

> [このたんぱく質は]脂肪を作る働きを抑え、ため込んだ分を[体に]使わせる効果があるそうだ。  
>  [This protein] is said to have a function of suppressing (your body's) fat
> production and making _[your body]_ use the fat it has stored.
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answer