text: [{"text_idx": "#000005", "text": "Currently, at least 35 glycoengineered antibodies, with their Fc fucose partially or entirely removed, have been investigated in animal models or clinical trials. The absence of fucose on the Fc N-glycan increases IgG1 Fc binding affinity to the Fc\u03b3RIIIa on immune effector cells like natural killer cells. It results in increased antibody-dependent cellular cytotoxicity (ADCC). [...]"}, {"text_idx": "#000006", "text": "Afucosylated mAb expression benefits therapeutic antibody efficacy"}]