<transcript><audio_251>egfrs form clusters so you can see in these view graphs clusters of egfr that uh we have been uh uh we have picturized so so now the egfr can be</transcript><caption><image_252>The image is a presentation slide from the Indian Institute of Technology, Kharagpur, India. It is titled "Nature of EGFR Activation". The slide has a title at the top that reads "EGFR can be activated in 2 ways". Below the title, there is a line graph that shows the relationship between the two methods.

The graph is divided into two sections. The left side of the slide has two lines, one in blue and the other in red. The blue line represents the anti-EGFR block, which is a type of block that helps to regulate the flow of energy in the body. The red line represents a block that is used to regulate energy levels in the water. The graph also has a legend that explains the meaning of each line. The legend explains that the image is meant to represent the different types of energy levels and how they interact with each other. 

There is also a small illustration at the bottom of the page that explains how the image can be used to explain the concept of EGfr activation.</caption><transcript><audio_253>activated in two ways one is Lian mediated uh another is Lian independent and flow induced the liant is the EGF so it is basically called as a Lian receptor model liant is the EGF and what binds with the</transcript><transcript><audio_254>liant the liant itself binds with its receptor that is the EGF receptor or egfr so you can use some antf which blocks only the Lian dependent activation and you can use a chemical</transcript><transcript><audio_255>which can block both Lian dependent and liant independent and flow induced activation now a very interesting point that we have observed is that below critical sheer stress the activation is</transcript><transcript><audio_256>purely Lian dependent fluid flow doesn't play a big role beyond the critical sheer stress the activation is predominantly Li and independent and primarily fluid flow induced so that is where you can see that the molecular</transcript> egfrs form clusters so you can see in these view graphs clusters of egfr that uh we have been uh uh we have picturized so so now the egfr can be activated in two ways one is Lian mediated uh another is Lian independent and flow induced the liant is the EGF so it is basically called as a Lian receptor model liant is the EGF and what binds with the liant the liant itself binds with its receptor that is the EGF receptor or egfr so you can use some antf which blocks only the Lian dependent activation and you can use a chemical which can block both Lian dependent and liant independent and flow induced activation now a very interesting point that we have observed is that below critical sheer stress the activation is purely Lian dependent fluid flow doesn't play a big role beyond the critical sheer stress the activation is predominantly Li and independent and primarily fluid flow induced so that is where you can see that the molecular
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