<transcript><audio_167>extract from this engineering platform effect of micro confinement now uh what are the effects of micro confinement that we are interested to</transcript><transcript><audio_168>environment one important aspect is tissue metric confinement so mechanical and chemical effects of interatial flows uh that can be carefully studied</transcript><transcript><audio_169>sheer stress near One Pascal is capable of affecting the cell physiology and PR proliferation not only that there are chemical effects also there are chemicals which are continuously secreted from</transcript><transcript><audio_170>cells so there are certain chemicals and we will study these very carefully these are uh these may be autocrine morphogens growth factors like EGF and all these these molecules bind to cell surface receptors so if you look into this</transcript><transcript><audio_171>cartoon these are the receptors and the red dots are the molecules which are called as lians which will bind to The receptors and</transcript> extract from this engineering platform effect of micro confinement now uh what are the effects of micro confinement that we are interested to environment one important aspect is tissue metric confinement so mechanical and chemical effects of interatial flows uh that can be carefully studied sheer stress near One Pascal is capable of affecting the cell physiology and PR proliferation not only that there are chemical effects also there are chemicals which are continuously secreted from cells so there are certain chemicals and we will study these very carefully these are uh these may be autocrine morphogens growth factors like EGF and all these these molecules bind to cell surface receptors so if you look into this cartoon these are the receptors and the red dots are the molecules which are called as lians which will bind to The receptors and
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