 This is our night. Shingles doesn't care, but Shingrix protects. Only Shingrix has proven over 90% effective. Shingrix is a vaccine used to prevent shingles in adults 50 years and older. Shingrix does not protect everyone and is not for those with severe allergic reactions to its ingredients or to a previous dose. An increased risk of Guillain-Barre syndrome was observed after getting Shingrix. Painting can also happen. The most common side effects are pain, redness, and swelling at the injection site, muscle pain, tiredness, headache, shivering, fever, and upset stomach. Ask your doctor or pharmacist about Shingrix today.