 and look at kind of like turning the knob of stress on the body and see does it accelerate a little bit like linearly or are some only appearing when you're in space longer. So we see early evidence of spaceflight like telomeres getting longer or stress on the body even within a few days, but some of the long-term immune changes or some of the other changes in how the body, bone loss, for example, take much longer and how the body responds to lack of gravity.