 They can be super hard on the gut, for one thing. They can actually ruin your gut barrier. So they might be solving your pain issue today, but they're actually making your gut leakier for tomorrow so that you are actually leaking more of these things across, increasing inflammation. In fact, I had a friend who's a holistic orthopedic surgeon down in Olympia, Dr. Mylon Moore, and he used to say, when I write someone for an NSAID, non-steroidal anti-inflammatory drug, they're called in medicine, which is things like ibuprofen, Aleve,