 There are definitely significant factors that we've begun to tease out. We don't know how big yet, or even some of the differences by sex for males versus females. We're only beginning to start to tease them out, but we do think there are factors that will become more important as we tease out how big of a factor they are. We do see differences, but we don't know how robust or reproducible they are yet. It's just too small of a sample.