 So a lot of what joint and muscle pain comes down to is actually what we call systemic inflammation. So it doesn't have to do with that joint or that muscle in particular, although it can manifest there if you've had trauma there. But it really has to go with how much overall inflammation you have. And we see this over and over again in clinical medicine. We have two people with the exact same MRI, but one person has hardly any pain and the other person is just crippled. And the reason for that is actually the inflammation difference between the two of them.