 before, during, and three weeks after a psychedelic trip on psilocybin. They found the brain disconnects from its typical pathways and reconnects to different parts of the brain. Those new pathways may be responsible for the success of some psychedelic drugs in treating mental health disorders like anxiety and depression. Psilocybin, also known as shrooms, is illegal under federal law, but the FDA has allowed it to be treated as a breakthrough medicine.