 Don't use if allergic to Skyrizzy. Serious allergic reactions and an increased risk of infections or a lower ability to fight them may occur. Before treatment, your doctor should check for infection and tuberculosis. Tell your doctor if you have an infection or symptoms such as fever, sweats, chills, muscle aches, or cough, or if you plan to or recently received a vaccine. With Skyrizzy, there's nothing like clearer skin and better movement, and that means everything.