 Fourth, in 2019, a novel SARS virus having a spike with extremely high binding affinity for human SARS receptors, a furin cleavage site inserted at the spike S1-S2 border, and a genome sequence with features enabling assembly from six synthetic nucleic acid building blocks using the reagent PSMB1, a virus having the exact features proposed in the 2018 NIH and DARPA proposals emerged on the doorstep of Wuhan Institute of Virology.