 If your constipation with belly pain keeps coming back, you may have irritable bowel syndrome with constipation or IBSC. Ask your doctor how Linzess can help you get ahead of it. Linzess Linaclotide is a prescription medicine that treats IBSC in adults. It's not a laxative. It's a once daily pill that helps you get ahead of your symptoms. It's proven to help you have more frequent and complete bowel movements and helps relieve overall abdominal symptoms, belly pain, discomfort, and bloating. These symptoms were studied in combination, not individually.