 The most common side effect is diarrhea, sometimes severe. If it's severe, stop taking Linzess and call your doctor right away. Other side effects include gas, stomach area pain, and swelling. Talk to your doctor and learn more at Linzess.com or call 1-800-L-A-N-Z-E-S-S. If you're looking for the latest local news and updated weather forecasts or current traffic conditions, you'll find it on 102.3 KRMG Tulsa's News and Talk. And if you don't have a radio around, don't sweat it. You can listen to KRMG anytime, anywhere on the TuneIn radio app.