 make it a pretty effective product against the weeds that you might have in your driveway. To totally sterilize an area, I don't know if that ground clear has a soil sterilant in it or not. I'd have to look on the label to see what actually is on the label. But there are some soil sterilants that you can look for. Pramitol is sold in a lot of seed stores and feed stores. Mostly pramitol is used.