 So we are still trying to work through that, but we do know that a state of obesity does lead to inflammation in the body, and we do know that inflammation can promote cancer. We also know that it can lead to things like insulin resistance, and the insulin signaling pathway is very important in the pathogenesis of many of these cancers. I think what's different here is that we do think exposure in early life to a risk factor is important for the subsequent risk of cancer in later adulthood. And as you know,