 95% range of motion back and pain was completely gone. And it hasn't come back. Rapamycin was first approved by the FDA for transplant patients in the 1990s. At high doses, it suppresses the immune system. At low doses, it seems to help tamp down inflammation. It works by inhibiting a pathway in the body called mTOR, which appears to be key to healthy aging. I can't rule out placebo effect, but I'm pretty sure it was real.