 and less depression, that's a win. Rexalti can cause serious side effects. Elderly dementia patients have an increased risk of death or stroke. Antidepressants may increase suicidal thoughts and actions and worsen depression in children and young adults. Report new or sudden changes in mood, behavior, thoughts, or feelings, or if you develop suicidal thoughts or actions. Report fever, stiff muscles, and confusion, which can be life-threatening, or uncontrolled muscle movements, which may be permanent.