 It can reduce or even eliminate oral steroids. And doesn't that make things better? Dupixen can cause allergic reactions that can be severe. Tell your doctor right away if you have rash, chest pain, worsening shortness of breath, tingling, or numbness in your limbs. Tell your doctor about new or worsening joint aches and pain or a parasitic infection. Don't change your stop asthma medicines, including steroids, without talking to your doctor.