 Big chunks of the country sliding back into stifling heat, and that could mean trouble for people who take certain types of medications. Bradley Phillips from the University of Florida's College of Pharmacy. Honestly, kind of thinking about heat as a quote-unquote medication that provides its own side effects, that in combination with other medications could definitely cause what we like to call like a perfect storm and increasing the risk of that patient experiencing side effects either from the heat or said medications. Some medications that could cause troubles include beta blockers and blood pressure pills.