 For moderate to severe vasomotor symptoms due to menopause, Vioza is the first and only prescription treatment that directly blocks the source of hot flashes and night sweats. With 100% hormone-free Vioza, you can have fewer hot flashes and more not flashes. Vioza reduces the number and severity of hot flashes day and night. Don't use Vioza if you have cirrhosis, severe kidney problems, kidney failure, or take CYP1A2 inhibitors.