 The drugstore chain currently runs more than 8,600 in the United States. Wentworth said the company's plan could include the closing of a significant portion of those roughly 2,100 underperforming stores if they don't improve. Walgreens and major competitors like CVS and Rite Aid, which is going through a bankruptcy reorganization, have been closing stores. They adjust to an array of challenges to their businesses. That includes years of tight reimbursement for their prescriptions and rising costs for running their locations.