 What exactly would have to happen to invoke the 25th Amendment in this country? Obviously, in an ideal world, you would try to invoke the 25th Amendment, which I think is amply justified. The man is deeply mentally unstable. The cabinet should convene immediately to discuss the 25th Amendment. If he's crazy and incompetent and stupid, then we have to look at the 25th Amendment. People in the president's inner circle have brought up the 25th Amendment at least 20 times. This is 25th Amendment kind of stuff.