 Health of the retina, specifically on the retinal arteries, when we talk about macular degen, wet macular degen, and diabetic retinopathy, there are inflammation in the back of the eye on the retina, where blood vessels start to bleed and break off, and they are also helpful for the macular degen in the back of the eye. So, cholomerase and 1250, both are very important for the eye.