 So that formula includes stain-fighting enzymes and odor-eliminating technology that are tough on stains and smells. After letting it pre-treat for about 5 to 10 minutes, you can throw that shirt into the washing machine. But before putting it into the dryer, you just want to double-check that stain. If you still see a little bit of stain left on there, you're going to want to pre-treat and wash again. Because once you put it in the dryer, it tends to set in and is a lot tougher to get out.