 He's advancing to his ninth major quarterfinals appearance. Number one seed Yannick Sinner also headed to the quarterfinals after defeating 14-seed American Ben Shelton in straight sets. Sinner will face five-seed Danil Medvedev. On the women's side of things, 12-seed American Madison Keyes had to retire in the third set of her fourth-round match due to a leg injury. 19-seed American Emma Navarro upset two-seed Coco Gauff in straight sets to advance to her first Grand Slam quarterfinal.