 That's right. So our adapter has two parts. One part is the part that finds the right piece of DNA, and the second part recruits in the silencing machinery that tells that gene to turn off. And you've done these experiments in mice. So just so I'm clear, presumably these mice didn't have the animal form of a prior disease, but you're able to see that it worked? What we're able to see is that we can get rid of the prion protein in the vast majority of the neurons.