 Thank you, Chris. We're joined by Dr. Ray Dorsey. He is the David M. Levy Professor of Neurology and Director of the Center for Health and Technology at the University of Rochester Medical Center. He's also one of the co-authors of Ending Parkinson's Disease, a Prescription for Action. Dr. Dorsey, let's start with maybe a bit of a primer for those who may not know everything there is to know about Parkinson's disease. Tell us a bit about the disease and the typical effects of it.