 Bromelain, that's an enzyme known to be an anti-inflammatory. MSM, a natural organic sulfur that is also just as important as glucosamine in rebuilding and repairing our joints. And so I put that all together in a cream that actually has no odor. It's greaseless. It doesn't freeze the pain. It doesn't burn the pain. It doesn't irritate your skin. Goes in, 15 minutes later, you have relief.