 That is until now. And I am now convinced that the science behind CaliCurb is so compelling that I can actually support it as a plausible alternative for curbing appetite and enhancing satiety to help you shed pounds. The active ingredient in CaliCurb, which is called Amerisate, comes from a specific New Zealand-grown hops flower, which works by activating your body's own appetite-regulating chemical messengers, including the famous GLP-1.