 You could if you wish. The premium root beers always seem to brag about the real sugar. You would have a hard time finding high-fructose corn syrup available in your local supermarket. They do sell corn syrup, but it's not high-fructose corn syrup. So you actually couldn't. You could try. But if anyone carries it in a supermarket, I would be astonished because it's just not used in home cooking.