 I've been using Collagenate now for about two and a half months, and I noticed a significant improvement and more mobility in my knees within about six to seven days. I've gone up several notches on my belt, so my clothes are becoming outdated now because I've lost quite a bit of weight. I've been taking Collagenate for three or four months now. I really like it. I've lost 21 pounds, and my joints are amazing.