text: Wile E. Coyote and the Road Runner appeared in the 1988 Touchstone/Amblin film Who Framed Roger Rabbit. They are first seen silhouetted by the elevator doors in Toontown, and then in full in the ACME Factory during the final scene with other characters.
  The 1979 Western comedy film The Villain is a tribute to the cartoons, reconstructing several famous gags in live action.
  In the Fraidy Cat episode "Choo Choo Fraidy", Fraidy Cat meets a coyote named Smile E. Coyote who prefers to not eat Fraidy and instead goes after an overweight jogging roadrunner, clearly parodying the iconic duo.
  In the 1992 film Under Siege, "Road Runner" is the code name of the renegade former CIA operative William Strannix, played by Tommy Lee Jones, in a reference to the fact that the character is never captured.
  Wile E. Coyote has appeared twice in Family Guy: his first episode, "I Never Met the Dead Man", depicts him riding in a car with Peter Griffin, when Peter runs over the Road Runner and asks if he hit "that ostrich", Wile E. tells him to keep going. His second appearance was in "PTV", in which Wile E. attempts to get a refund for a giant-sized slingshot at an ACME retailer where Peter works.