text: Revival On February 21, 2001, Cartoon Network issued a press release stating that Dexter's Laboratory had been revived for a 13-episode third season. The series was given a new production team at Cartoon Network Studios, and Chris Savino took over the role of creative director from Tartakovsky, who at the time was immersed in launching his next series, Samurai Jack. During season four of Dexter's Laboratory, Savino was promoted to producer giving him further control of the series, including the budget. Revival episodes featured revised visual designs and sound effects, recast voice actors, continuity shakeups, and a transition from traditional cel animation, which was used until Ego Trip, to digital ink and paint, which was used permanently beginning with season three's premiere.
  Christine Cavanaugh voiced Dexter for early episodes of season three, but she retired from voice acting in 2001 for personal reasons. She was replaced by Candi Milo. Allison Moore, a college friend of Tartakovsky, was cast as Dee Dee. Moore's role was later recast with Kat Cressida. In season three, Moore briefly returned to voice Dee Dee before Cressida again assumed her role for season four. Character redesigns were handled with the help of one of Dexter's original model designers, Chris Battle, known individually for acting as character designer for Nickelodeon's Aaahh!!! Real Monsters and Cartoon Network's The Powerpuff Girls. Aaron Springer and Chris Reccardi are credited on the writing staff, as is Family Guy creator Seth MacFarlane.
  In 2023, Tartakovsky said he was uninterested in attempting to reboot Dexter's Laboratory due to Cavanaugh's death in 2014.
  Episodes
  Dexter's Laboratory broadcast 78 half-hour episodes over 4 seasons during its 7-year run. Four pilot shorts were produced for What a Cartoon! that aired from 1995 to 1996, and were reconnected into season one in later airings. Fifty-two episodes were produced from 1996 to 1998, followed by Ego Trip in 1999.