text: After racing out to a 7–3 start, the Titans suffered a late-season collapse. They ended the season on a brutal seven-game losing streak, their worst losing streak since 2015. The Titans failed to improve on their 12–5 record from last season. They also suffered their first losing season since 2015 and missed the playoffs for the first time since 2018 after a loss to the Jacksonville Jaguars in the final week of the season. It was the fourth time in franchise history they missed the playoffs after having a first-round bye in the playoffs the previous season (1994, 2001, and 2009).
  Inconsistent play and a number of key injuries hindered the Titans throughout the season, including injuries to starting quarterback Ryan Tannehill who missed five games, Taylor Lewan who missed 15 games, and Harold Landry who missed the entire season. The Titans finished the season with a league-high 23 players on injured reserve.
  Records
  Retired numbers
  (*)Began his tenure in Houston
  Pro Football Hall of Fame members
  (*) Indicates Player and/or coach began their tenure with the Houston Oilers
  Titans Hall of Fame
  Bud Adams established the Titans/Oilers Hall of Fame after the 40th season of the franchise to honor past players and management
  (*) Indicates This Player or Coach Began Their Tenure in Houston