text: In the third quarter, a Marshawn Lynch touchdown run and a goal line stand by the Bills made the score 21–17 Bills heading into the final quarter.  However, the Giants ran away with the contest in the fourth.  With 14:05 to go in the 4th, Trent Edwards's pass was deflected and intercepted by linebacker (and future Bill) Kawika Mitchell, who returned it 20 yards for a touchdown for the go-ahead score.  With 6:27 to go, the Giants got the ball back on their own 12-yard line.  During the second half, rookie 7th-round pick Ahmad Bradshaw, who seldom played outside of special teams before this game but who now had an opportunity due to Derrick Ward's injury and Reuben Droughns's declining play, checked into the game.  Bradshaw (who, unusual for a Giant, played with a single "y" on one side of his helmet instead of the standard "ny" in this game) received a handoff towards the left side of the line, cut towards the left sideline, received a key block from receiver Plaxico Burress, and sprinted down the sideline 88 yards for a touchdown to make it 31–21.  Bradshaw's run is the third-longest in Giants history, with Tiki Barber's 95-yard touchdown against the Raiders on New Year's Eve 2005 being the longest.  Just three plays later, Trent Edwards was intercepted by cornerback Corey Webster, who returned Edwards's errant pass 34 yards for the game-clinching touchdown.
  While Eli Manning played poorly again, going 7–15 for just 111 yards with two interceptions and four fumbles (two lost), Trent Edwards also had a poor performance, going just 9-26 for 161 yards.  Although he threw for 2 touchdowns, he also threw 3 interceptions (2 returned for touchdowns) and fumbled twice (though both were recovered by other Bills), and was just 3–19 after his first two drives.  Ahmad Bradshaw ran for 151 yards on just 17 carries, while Brandon Jacobs ran for a career-high 143 yards on 25 carries with 2 touchdowns.  Another important stat to note is that all 59 points in the game were scored going towards the east end zone.
  With the win, the Giants improved to 10–5 to clinch their third consecutive playoff berth. They also secured the 5th seed when the Washington Redskins defeated the Minnesota Vikings later that night.
  Week 17: vs. New England Patriots