text: (1956–59) François Heutte (1957–59, 65–66)
  René Fatoux (1957–62)
  André Guy (1965–67)
  Christian Coste (1973–77)
  Stanislav Karasi (1974–77)
  Žarko Olarević (1977–81)
  Pierre Pleimelding (1977–81)
  Dušan Savić (1983–85)
  Erwin Vandenbergh (1986–90)
  Abedi Pele (1988–90)
  Per Frandsen (1990–94)
  Éric Assadourian (1990–95)
  Antoine Sibierski (1992–96)
  Kennet Andersson (1993–94)
  Djézon Boutoille (1993–2004)
  Matt Moussilou (2001–06)
  Nicolas Fauvergue (2003–11)
  Kevin Mirallas (2004–08)
  Peter Odemwingie (2004–07)
  Kader Keïta (2005–07)
  Michel Bastos (2006–09)
  Eden Hazard (2007–12)
  Patrick Kluivert (2007–08)
  Ludovic Obraniak (2007–12)
  Túlio de Melo (2008–14)
  Róbert Vittek (2008–10)
  Pierre-Alain Frau (2008–11)
  Pierre-Emerick Aubameyang (2009–10)
  Gervinho (2009–11)
  Moussa Sow (2010–12)
  Salomon Kalou (2012–14)
  Divock Origi (2012–15)
  Nolan Roux (2012–15)
  Sofiane Boufal (2015–16)
  Eder (2016–18)
  Martin Terrier (2016–18)
  Luiz Araújo (2017–21)
  Lebo Mothiba (2017–18)
  Nicolas Pépé (2017–19)
  Jonathan Ikoné (2018–22)
  Jonathan Bamba (2018–23)
  Rafael Leão (2018–19)
  Loïc Rémy (2018–20)
  Victor Osimhen (2019–20)
  Timothy Weah (2019–23)
  Burak Yılmaz (2020–22)
  Notable past line-ups
  Club officials
  Owner of Lille Olympique Sporting Club – LOSC Lille:  Merlyn Partners SCSp
  Board of directors
  First-team coaching and medical staff
  Source:
  Reserves and academy personnel
  Coaching history
  The following is a list of Lille OSC head coaches from the foundation of the club in 1944, until the present day.
  Records and statistics
  Managerial records
  Winning head coaches
  Players records
  Most appearances
  Source:
  Transfers records
  Highest transfer fees paid