text: Panayiota Bertzikis, B.A. 2010, Humanitarian.
  Daniel E. Bosley, (M.S. 1996), Member of the Massachusetts House of Representatives (1987–2011).
  Edward Scott Bozek (1950–2022), Olympic épée fencer
  William Bratton, B.A. 1975, Boston City Police Commissioner (1993–1994), New York City Police Commissioner (1994–1996; 2014–2016), Los Angeles Police Department Chief (2002–2009), Member of the Homeland Security Advisory Council (2011–Present).
  Phillip Brutus, B.S. 1982, Member of the Florida House of Representatives (2001–2007).
  Christine Canavan, (B.S. Nursing (summa cum laude) 1988), Member of the Massachusetts House of Representatives (1993–2015).
  Ken Casey, bassist for the punk rock group the Dropkick Murphys.
  Lenny Clarke, (did not finish), comedian/actor.
  Tim Costello (1945–2009), labor and anti-globalization advocate and author.
  Paul Donato, Mayor of Medford, Massachusetts (1980–1985), Member of Massachusetts House of Representatives (2001–Present), Second Assistant Majority Whip of the Massachusetts House of Representatives (2009–Present).
  Paul M. English, B.A. 1987 and M.S. 1989 (both in Computer Science), co-founder and CTO of Kayak.com.
  Jennifer L. Flanagan, (B.S. Political Science, 1998), Member of the Massachusetts House of Representatives (2005–2009), Member of the Massachusetts Senate (2009–2017).
  Jovita Fontanez 1984, head of Boston Election Commission, member of Massachusetts Electoral College.
  Beth Harrington, filmmaker and musician
  Robert L. Hedlund, Member of the Massachusetts Senate (1991–1993; 1995–2016), Mayor of Weymouth, Massachusetts (2016–Present).