text: Sammy Baugh, QB (1963) Washington Redskins 1937–1952
  Bob Lilly, DT (1980) Dallas Cowboys 1961–1974
  LaDainian Tomlinson, RB (2017) San Diego Chargers 2001–2009 New York Jets 2010–2011
  National Football League Most Valuable Player award
  LaDainian Tomlinson, RB (2006) San Diego Chargers
  Super Bowl Most Valuable Player award
  Larry Brown, CB (1996) Dallas Cowboys
  Canadian Football League Most Outstanding Player award
  Casey Printers, QB (2004) BC Lions
  Grey Cup Most Valuable Player award
  Jason Tucker, WR (2003) Edmonton Eskimos
  Horned Frogs in the NFL
  As of December 19, 2023, there are 19 former TCU Football players on NFL active rosters.
  Steve Avila, G Los Angeles Rams
  Ross Blacklock, DT Tennessee Titans
  Emari Demercado, RB Arizona Cardinals
  Andy Dalton, QB Carolina Panthers
  Derius Davis, WR Los Angeles Chargers
  Jerry Hughes, DE Houston Texans
  Quentin Johnston, WR Los Angeles Chargers
  Kendre Miller, RB New Orleans Saints
  Trevon Moehrig, S Las Vegas Raiders
  Lucas Niang, OT Kansas City Chiefs
  Joseph Noteboom, OT Los Angeles Rams
  Matt Pryor, G San Francisco 49ers
  Jalen Reagor, WR New England Patriots
  Austin Schlottmann, C Minnesota Vikings
  Ty Summers, LB New Orleans Saints
  Tre Tomlinson, CB Los Angeles Rams
  KaVontae Turpin, WR Dallas Cowboys
  Garret Wallow, LB Tennessee Titans
  Dee Winters, LB San Francisco 49ers