text: Godín was selected by coach Óscar Tabárez for the 2014 World Cup and captained the team in three of their four games due to Lugano's absence through injury. On 24 June, he headed the only goal against Italy in the final group fixture, sending the country through to the knockout stage.
  In May 2015, Godín was named as captain for Uruguay's defence of the Copa América during the 2015 continental tournament in Chile. He was also picked for the Copa América Centenario squad, heading home from a Carlos Sánchez long cross in the opener against Mexico where both teams ended with ten players (1–3 loss). He won his 100th cap in the following match, a 0–1 defeat to Venezuela at the Lincoln Financial Field.
  Godín was also selected for the 2018 World Cup. The following 25 March, at the 2019 China Cup, he made his 126th appearance against Thailand, surpassing Maxi Pereira as the most capped player in the national team's history.
  In June 2019, Godín skippered the team to the quarter-finals of the Copa América in Brazil. He repeated the feat two years later, in the same country. He played the full 90 minutes of his 150th cap on 10 October 2021, a 3–0 loss away to Argentina in 2022 World Cup qualification.
  He was also selected for the 2022 World Cup, being their captain in 2 of Uruguay’s games before being dropped in the 3rd one.