text: Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone (DHEA) is a steroid hormone produced by the adrenal glands (and by the testes in men), which can be converted in the body to male and female sex hormones, including estrogen and testosterone.  DHEA is used to treat a variety of conditions (without FDA approval) including aging, Alzheimer's disease, schizophrenia, erectile dysfunction, systemic lupus erythematosus, and for aiding in weight loss. There is insufficient data to support DHEA’s efficacy for weight loss.  The DHEA content in the daily recommended dose of Dexatrim Max ranges from 100–200 mg per day. Side effects at this dose can include acne, hair loss, facial hair growth and deeper voice in women, stomach upset, and high blood pressure, particularly if the supplement is used for a longer period of time.  There are many conditions in which DHEA use has special precautions and warnings. These include pregnancy and breast-feeding, hormone-sensitive conditions and cancers, liver problems, diabetes, and cholesterol problems.  DHEA use is banned by the National Collegiate Athletic Association (NCAA).
  History of Dexatrim
  Dexatrim has been on the market for more than 30 years. The brand was originally owned by Thompson Medical, which was acquired by Chattem in 1998. It is now part of Sanofi. Dexatrim formula has changed considerably over the years.  In prior formulations, Dexatrim contained the decongestant phenylpropanolamine (PPA) and the amphetamine-like compound ephedra.
  A 2000 study by Yale University School of Medicine showed an increased risk of hemorrhagic stroke with taking PPA.  A case of myocardial injury was also reported using Dexatrim (with PPA) at doses recommended for weight control. In 2000, following the request of the FDA to discontinue marketing drug products containing PPA, Dexatrim dropped PPA from its formula.