text: Plot Each episode found the Pussycats and crew en route to perform a gig or record a song in some exotic location where, somehow, often due to something Alexandra did, they became mixed up in an adventure. The antagonist was always a diabolical mad scientist, spy, or criminal who wanted to take over the world using some high-tech device. The Pussycats usually found themselves in possession of the plans for an invention, an item of interest to the villains, a secret spy message, etc., and the villains chased them to retrieve it. Eventually, the Pussycats would ruin the villain's plans, resulting in a final chase sequence set to a Pussycats song. With the villain captured, the Pussycats would return to their gig or recording session, and the final gag was always one of Alexandra's failed attempts to interfere with the Pussycats' performance or steal Alan away from Josie.
  Characters
  Josephine "Josie" McCoy (voiced by Janet Waldo, singing voice provided by Kathleen Dougherty) – The red-headed lead singer, songwriter, guitarist, and leader of the band. Josie shares an attraction with Alan, the road manager. During the 1970s, the character was known as Josie James. (Judy Waithe was originally cast but replaced before the show debuted, as her readings of the Josie and the Pussycats-hosted In the Know interstitials were not to CBS's liking; she is incorrectly credited in some copies of the episodes.)