text: Deep learning reconstruction Deep learning methods are widely applied to image reconstruction nowadays and have achieved impressive results in various image reconstruction tasks, including low-dose denoising, sparse-view reconstruction, limited angle tomography and metal artifact reduction. An excellent overview can be found in the special issue  of IEEE Transaction on Medical Imaging. One group of deep learning reconstruction algorithms apply post-processing neural networks to achieve image-to-image reconstruction, where input images are reconstructed by conventional reconstruction methods. Artifact reduction using the U-Net in limited angle tomography is such an example application. However, incorrect structures may occur in an image reconstructed by such a completely data-driven method, as displayed in the figure. Therefore, integration of known operators into the architecture design of neural networks appears beneficial, as described in the concept of precision learning. For example, direct image reconstruction from projection data can be learnt from the framework of filtered back-projection. Another example is to build neural networks by unrolling iterative reconstruction algorithms. Except for precision learning, using conventional reconstruction methods with deep learning reconstruction prior  is also an alternative approach to improve the image quality of deep learning reconstruction.
  Tomographic reconstruction software
  Tomographic systems have significant variability in their applications and geometries (locations of sources and detectors). This variability creates the need for very specific, tailored implementations of the processing and reconstruction algorithms. Thus, most CT manufacturers provide their own custom proprietary software. This is done not only to protect intellectual property, but may also be enforced by a government regulatory agency. Regardless, there are a number of general purpose tomographic reconstruction software packages that have been developed over the last couple decades, both commercial and open-source.
  Most of the commercial software packages that are available for purchase focus on processing data for benchtop cone-beam CT systems. A few of these software packages include Volume Graphics, InstaRecon, iTomography, Livermore Tomography Tools (LTT), and Cone Beam Software Tools (CST).
  Some noteworthy examples of open-source reconstruction software include: Reconstruction Toolkit (RTK),  CONRAD, TomoPy, the ASTRA toolbox, PYRO-NN, ODL, TIGRE, and LEAP.