text: On 9 February 2006, a freight train hauled by English Welsh & Scottish 66017, derailed at Brentingby Junction near Melton Mowbray. Having passed a signal at danger, the locomotive and the first three wagons were derailed at catch points at the end of the Up Goods Loop. There were no injuries.
  On 4 January 2010, a freight train, hauled by 66048, derailed at Carrbridge in snowy weather, blocking the Highland Main Line. Having passed a signal at danger the train was derailed at trap points, subsequently falling down an embankment into trees and injuring the two crew members. The locomotive was hauling container flats from Inverness to Mossend Yard on behalf of Stobart Rail. The line was reopened on 12 January.
  On 21 November 2011, 66111 derailed between Exeter Central and Exeter St Davids on working an engineering works service.
  On 28 June 2012, GBRf operated 66734 derailed at Loch Treig whilst working the 6S45 North Blyth to Fort William Alcan Tanks. Due to its position and the environmental risks associated with recovery, after agreement from owners Porterbrook it was cut-up on site and the mechanics recycled as spare parts.
  On 1 August 2015, 66428 was hauling an engineering train that ran into the rear of another engineering train at Logan, Ayrshire. It was severely damaged. The train that was run into was hauled by 66305.