text: Eddie Egan – actor and former police detective who was the subject of the nonfiction book The French Connection and its 1971 film adaptation
  David Eigenberg – actor (Sex and the City)
  Ronald "R." Lee Ermey – Golden Globe-nominated actor (Full Metal Jacket) and host of Mail Call
  Nicholas Estavillo – NYPD Chief of Patrol (Ret.); became in 2002 the first Puerto Rican and the first Hispanic in the history of the NYPD to reach the three-star rank of Chief of Patrol
  Lacey Evans – female professional wrestler best known for her career in WWE
  Don Everly – Grammy Award-winning musician, member of Rock & Roll Hall of Fame
  Phil Everly – Grammy Award-winning musician, member of Rock & Roll Hall of Fame
  F
  Hussein Mohamed Farrah – son and successor of Somali warlord Mohamed Farrah Aidid
  Mike Farrell – Emmy Award-nominated actor and DGA Award-nominated television director (M*A*S*H)
  Freddie Fender – Grammy Award-winning Tejano music recording artist
  Bob Ferguson – songwriter, record producer, and historian
  Jesse Ferguson – heavyweight boxer
  Nathaniel Fick – diplomat and technology entrepreneur
  Morris Fisher – five-time Olympic gold medalist for shooting
  Bill Fitch – basketball coach
  Pat Flaherty – actor and pro football and baseball player (The Asphalt Jungle, Harvey)
  Shelby Foote – author, American Civil War historian