text: The show has been credited for kick-starting the channel's ascent and launching Tartakovsky's career, which later gave way to Samurai Jack and Star Wars: Clone Wars. To this, Gizmodo contributor Beth Elderkin added: "Since then, he's become a staple in children's and adult animation, responsible for everything from the Hotel Transylvania series to the powerful (and ultra-violent) Primal." Vulture called the first pilot episode "a testament to Tartakovsky's talent and commitment as a filmmaker and a proof of concept for the What a Cartoon! anthology format." For a while, the show's simplistic look was adopted by other American cartoons; in a 2021 interview with Syfy Wire, animator Butch Hartman said, "When I started making Fairly OddParents, I took cues from what Genndy did in terms of simplifying the designs and using bold colors and simple shapes."
  Awards and nominations
  Merchandise
  Home media
  Dexter's Laboratory first appeared in home media as a "bonus toon" on the Jonny Quest - Race Bannon in Army of One VHS and later in a limited-run, complete series Dexter's Laboratory DVD contest prize, both of which became available in 1999. Dedicated, wide-release home media for the series began with the Dexter's Laboratory: Volume 1 VHS in the United Kingdom in 2000 and the Dexter's Laboratory: Greatest Adventures VHS in North America in 2001. The made-for-television movie Ego Trip was released exclusively on VHS in North America in 2000 and in the United Kingdom in 2001. Episodes from the series have been included as extra content in other Cartoon Network series' home media releases or as part of Cartoon Network's compilation DVDs.