	The region is very fertile, especially for grains, fruits and grapes (famous "prokupačko vino", wine of Prokuplje). The central part of the region occupies "Toplička (or Prokupačka) kotlina" (Depression of Toplica/Prokuplje), between the mountains of Veliki Jastrebac from the north and Sokolovica, Vidojevica and Pasjača from the south, with many smaller settlements on the river: Donje Krmčare, Grabovnica, Bogojeva, Barlovo, Donje Točane, Donji Pločnik, Tulare, Donja Konjuša, Donja Toponica, and the center of the whole region, the city of Prokuplje. The river continues on the northern slopes of mountain Pasjača, next to the villages of Podina, Voljčince, Badnjevac and the smaller regional center Žitorađa. After the Toplica reaches municipal center of Doljevac, it enters the most densely populated part of the south Pomoravlje, turns north and flows into the Južna Morava at the village of Orljane, across the medieval ruins of Kurvin grad, as Južna Morava's longest left tributary.