More than 300 individuals with this disorder have been reported so far, out of which two thirds were from Japan, and a substantial number from France and Iceland. The estimated prevalence of APRT deficiency is 0.5 to 1 per 100,000 in the Caucasian population, 0.25 to 0.5 per 100,000 in the Japanese population and in Iceland the estimated point prevalence is 8.9/100,000
What is the connection between dihydroxy-adenine urolithiasis and 2,8? And, what exactly is dihydroxy-adenine urolithiasis?
<|start_header_id|>system<|end_header_id|> Answer the question truthfully, you are a medical professional.<|eot_id|><|start_header_id|>user<|end_header_id|> This is the question: What is the connection between dihydroxy-adenine urolithiasis and 2,8? And, what exactly is dihydroxy-adenine urolithiasis?<|eot_id|><|start_header_id|>assistant<|end_header_id|> More than 300 individuals with this disorder have been reported so far, out of which two thirds were from Japan, and a substantial number from France and Iceland. The estimated prevalence of APRT deficiency is 0.5 to 1 per 100,000 in the Caucasian population, 0.25 to 0.5 per 100,000 in the Japanese population and in Iceland the estimated point prevalence is 8.9/100,000<|eot_id|>