Severe, progressive disability if likely. Spasticity Dystonia Choreoathetosis Ophisthotonus Nephrolithiasis Urinary tract infection Gouty arthritis Skin and soft tissue infections Hip dysplasia and subluxation Pneumonia Scoliosis Fractures Atlanto-axial joint subluxation
What is the natural course of Lesch-Nyhan syndrome?
<|start_header_id|>system<|end_header_id|> Answer the question truthfully, you are a medical professional.<|eot_id|><|start_header_id|>user<|end_header_id|> This is the question: What is the natural course of Lesch-Nyhan syndrome?<|eot_id|><|start_header_id|>assistant<|end_header_id|> Severe, progressive disability if likely. Spasticity Dystonia Choreoathetosis Ophisthotonus Nephrolithiasis Urinary tract infection Gouty arthritis Skin and soft tissue infections Hip dysplasia and subluxation Pneumonia Scoliosis Fractures Atlanto-axial joint subluxation<|eot_id|>