Interleukin 13 receptor, alpha 1 [SEP] found in taxon
Interleukin 13 receptor, alpha 1
Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene.
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase
one hairpin, while the second and third form the other hairpin- each hairpin forms another arm of the "Y" and the long loop forms its trunk.
The beta barrel has a 16 Å diameter, and is filled with amino acid side-chains.
Occurrence.
Among other proteins, β trefoil fold is found in Kunitz inhibitors of several plants such as soybean, "Erythrina caffra" and wheat; in members of the interleukin 1 cytokine family (interleukin-1 alpha, interleukin-1 beta and interleukin-1 receptor antagonist);