Calitoxin [SEP] found in taxon
Calitoxin
Calitoxin, also known as CLX, is a sea anemone neurotoxin produced by the sea anemone "Calliactis parasitica". It targets crabs and octopuses, among other invertebrates. Two isoforms (CLX-1 and CLX-2) have been identified, both of which are formed from precursors stored in the stinging cells of the anemone. Once the toxin is activated and released, it causes paralysis by increasing neurotransmitter release at invertebrate neuromuscular junctions. Along with several other toxins derived from anemones, CLX is useful in ion channel research. Certain structural
Sea anemone neurotoxin
Sea anemone neurotoxin is the name given to neurotoxins produced by sea anemones with related structure and function.
Sea anemone neurotoxins can be divided in two functional groups that either specifically target the sodium channel or the potassium channel.
A number of proteins belong to the sodium channel toxin family, including "calitoxin" and "anthopleurin". The neurotoxins bind specifically to the sodium channel, thereby delaying its inactivation during signal transduction, resulting in strong stimulation of mammalian cardiac muscle contraction. Calitoxin 1 has been found