Hellas Planitia [SEP] located on astronomical body
Hellas Planitia
Hellas Planitia is a plain located within the huge, roughly circular impact basin Hellas located in the southern hemisphere of the planet Mars. Hellas is the third or fourth largest impact crater and the largest visible impact crater known in the Solar System. The basin floor is about deep, deeper than the Moon's South Pole-Aitken basin, and extends about east to west. It is centered at Hellas Planitia is in the Hellas quadrangle and the Noachis quadrangle.
Description.
With a diameter of about ,
blocking of the beta-lactam ring. Cefuroxime was the first cephalosporin to incorporate this side chain. Another very important group in the second generation is the aminothiazole ring to the C-3 side chain. This development drastically increased binding affinity to PBP and increased antimicrobial activity. The aminothiazole ring can be seen in the structure of Cefotiam.
Drug development 3rd generation cephalosporins.
The majority of third generation cephalosporins have the aminothiazole group at position C-7. Different groups are found at the 7-α-position like 7-α-iminohydroxy and 7-α-iminomethoxy