DC-SIGN [SEP] found in taxon
HIV infection.
This molecule is involved in the initial stages of the human immunodeficiency virus infection, as the HIV gp120 molecule causes co-internalization of the DC-SIGN molecule and HIV virus particle (virion). The dendritic cell then migrates to the cognate lymphoid organ, whereupon recycling of the DC-SIGN/HIV virion complex to the cell periphery facilitates HIV infection of CD4 T cells by interaction between DC-SIGN and ICAM-3.
Gene family.
DC-SIGN/CD209 is an animal "C-
There is no sign of a postfrontal bone, which is interpreted as fusing with the postorbital bone during ontogeny in other dicynodonts. Thirdly, the preparietal is small relative to the size of skull, unlike the large preparietal found in juvenile dicynodonts. These traits indicate that the holotype of "Thliptosaurus" is not a juvenile of a larger taxon, despite its small size, and represents a mature, small bodied dicynodont.
History of discovery.
The holotype and only known specimen of "Thliptosaurus", BP/1/2796, was discovered