DEFA6 [SEP] chromosome
bacteria.
Several alpha defensin genes, including "DEFA6", are clustered on chromosome 8.
External links.
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Defensin-6
DEFA6
Defensin, alpha 6 (DEFA6) also known as human alpha defensin 6 (HD6) is a human protein that is encoded by the "DEFA6" gene. "DEFA6" is expressed in the Paneth cells of the ileum.
Function.
The alpha defensins are a family of microbicidal and cytotoxic peptides that defend the host against bacteria and viruses. HD6 has poor antibacterial potency. However, HD6 affords protection against invasion by enteric bacterial pathogens by self-assembly to form fibrils and nanonets that surround and entangle