Zinc-activated ion channel [SEP] found in taxon
Zinc-activated ion channel
Zinc-activated ion channel (ZAC), is a human protein encoded by the gene. ZAC forms a cation-permeable ligand-gated ion channel of the "Cys-loop" superfamily. The ZAC gene is present in humans and dogs, but no ortholog is thought to exist in the rat or mouse genomes.
ZAC mRNA is expressed in prostate, thyroid, trachea, lung, brain (adult and fetal), spinal cord, skeletal muscle, heart, placenta, pancreas
receptor antagonists
- NMDA receptor antagonists
Channel blockers are also known to act at AMPA receptors, Glycine receptors, Kainate receptors, P2X receptors and Zinc (Zn)-activated channels. The type of inhibition mediated by channel blockers may be referred to as noncompetitive or uncompetitive.
See also.
- Ion channel
- Channel opener