ATP6AP1 [SEP] found in taxon
ATP6AP1
The human gene ATP6AP1 encodes the S1 subunit of the enzyme V-type proton ATPase.
This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is composed of a cytosolic, V, (site of the ATP catalytic site) and a transmembrane, V, domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded
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- Robert Jan 'Roy' van de Hoek: "Restoration and Recovery for Elna Bakker and Ivan Johnston. "R&R" for the Playa del Rey Frogs and Plants." 2005