CDH2 [SEP] found in taxon
CDH2
N-cadherin, also known as Cadherin-2 (CDH2) or neural cadherin (NCAD) is a protein that in humans is encoded by the "CDH2" gene. CDH2 has also been designated as CD325 (cluster of differentiation 325). N-cadherin is a transmembrane protein expressed in multiple tissues and functions to mediate cell–cell adhesion. In cardiac muscle, N-cadherin is an integral component in adherens junctions residing at intercalated discs, which function to mechanically and electrically couple adjacent cardiomyocytes. While mutations in
the role of Cdh2 in controlling adhesion of neuroepithelial cells possibly contributes to the FBMN migration defects found in Cdh2-depleted embryos, Cdh2-mediated cohesion between different FBMNs and also between FBMNs and the MLF may also be crucial for the migration process.
The role of cadherins In "Caenorhabditis elegans".
FMI-1 is a cadherin and an adhesion G-protein coupled receptor in "C. elegans", ortholog of "Drosophila"’s flamingo and vertebrate celsr genes, with a highly conservative structure, divided in extra- and intracellular domains. It is a