CCR2 [SEP] found in taxon
an acute ischemic event happens during the active phase, monocytes are more susceptible to invade the heart . An excessive monocytes infiltration generates higher inflammation and increases the risk of heart failure.
Clinical significance.
In an observational study of gene expression in blood leukocytes in humans, Harries "et al." found evidence of a relationship between expression of "CCR2" and cognitive function (assessed using the mini-mental state examination, MMSE). Higher "CCR2" expression was associated with worse performance on the MMSE assessment of
or group of gene variants, may produce different effects in different populations depending on differences in the gene variants, or groups of gene variants, they interact with. One example is the rate of progression to AIDS and death in HIV–infected patients. In Caucasians and Hispanics, HHC haplotypes were associated with disease retardation, particularly a delayed progression to death, while for African Americans, possession of HHC haplotypes was associated with disease acceleration. In contrast, while the disease-retarding effects of the CCR2-641 allele were found