C11orf73 [SEP] chromosome
HIKESHI
HIKESHI is a protein important in lung and multicellular organismal development that, in humans, is encoded by the "HIKESHI" gene. HIKESHI is found on chromosome 11 in humans and chromosome 7 in mice. Similar sequences (orthologs) are found in most animal and fungal species. The mouse homolog, lethal gene on chromosome 7 Rinchik 6 protein is encoded by the "l7Rn6" gene. When the l7Rn6 protein is disrupted in mice, the mice display severe emphysema at birth as a result of disorganization of the Golgi
the EST Profile on UniGene, only 11 tissues were shown not to express C11orf73, most likely due to small sample sizes in the tissue.
Protein.
The human HIKESHI gene encodes for a protein called uncharacterized protein C11orf73. The homologous mouse L7rn6 gene encodes a protein called lethal gene on chromosome 7 Rinchik 6.
The encoded human protein is 197 amino acids long and weighs 21,628 Daltons. Through analogy to the mouse protein, the hypothetical function of the human HIKESHI protein is the organization and function of the secretory apparatus