Myc [SEP] found in taxon
Myc
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The "Myc" family consists of three related human genes: "c-myc", "l-myc" (MYCL), and "n-myc" (MYCN). "c-myc" (also sometimes referred to as "MYC") was the first gene to be discovered in this family, due to homology with the viral gene "v-myc".
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proteins. Normally, c-Myc is highly expressed in immature cells but has almost no perceivable expression in mature/differentiated cells. Its roles in the cell cycle and apoptosis help cells maintain an immature state, and its expression wanes as cells begin to differentiate. Bmi-1 and Myc were found to be partners within the cell nucleus. Bmi-1 and c-Myc seem to function in tandem in multiple ways. Studies have found that together c-Myc and Bmi-1 possess the ability to alter tumor suppressor genes. Hypoactive c-Myc