CLCC1 [SEP] found in taxon
CLCC1
Chloride channel CLIC-like 1 also known as CLCC1 is a human gene.
The protein encoded by this gene is a chloride channel which is related in sequence to the "S. cerevisiae" MID-1 stretch-activated channel. CLCC1 is located in the membranes of intracellular compartments including endoplasmic reticulum and the Golgi apparatus. It is highly expressed in the testis and moderately in the spleen, liver, kidney, heart, brain, and lung.
or CLCC1.)
The six K2P channel subfamilies are regulated by various physical, cellular, and pharmacological stimulants, including membrane stretch, heat, pH change, calcium flux, and protein kinases.
Clinical relevance.
Stretch-activated ion channels perform important functions in many different areas of our body. Pressure-dependent myogenic constriction resistance arteries require these channels for regulation in the smooth muscle of the arteries. They have been found to be used for volume sensing in animals and blood pressure regulation. Bacteria have been shown