ZNF184 [SEP] chromosome
ZNF184
Zinc finger protein 184, also known as ZNF184, is a protein that in humans is encoded by the "ZNF184" gene on chromosome 6. It was first identified by Goldwurm "et al." in 1996.
The National Center for Biotechnology Information (NCBI) Gene database entry for "ZNF184" identifies conserved domains KRAB_A (Krüppel associated box) near the N-terminus and Zn-finger (Zinc finger) at the C-terminus of the translated protein. The former is associated with transcription repression
and the latter with DNA binding (see Zinc finger).
Domains and Structure.
The figure below is a reformatted and annotated conceptual translation display of "ZNF184"'s Consensus CDS. CCDS displays exons in alternating black and blue font, with red indicating a residue coded across a splice boundary.
ZNF184 has 19 zinc finger motifs at the end of its final and longest exon. The figure shows regularity among the fingers in this protein, including the 2 columns of green-highlighted Cysteine residues and the 2 columns