ZDHHC2 [SEP] found in taxon
ZDHHC2
Zinc finger, also known as ZDHHC2, is a human gene.
, S-palmitoylation, on cysteine 100 of its cytoplasmic domain. So far only the palmitoyl-acyltransferase ZDHHC2 has been identified as a potential regulator of CLIMP-63’s palmitoylation but as ZDHHC2 resides mostly at the plasma membrane, supplementary investigations are needed. The consequence of S-palmitoylation remain to be investigated but could play a role in the cell cycle as CLIMP-63’s palmitoylation was reported to strongly increase during mitosis.
Finally, CLIMP-63 has been shown by different groups to serve as a cell surface receptor for various extracellular ligands,