GPR113 [SEP] chromosome
GPR113
GPR113 is a gene that encodes the Probable G-protein coupled receptor 113 protein.
Gene.
The "Homo sapiens" GPR113 gene is located on chromosome 2 (2p23.3). This gene spans the length of a 38.65kb region from base 26531041 to 26569685 on the negative strand. The GPR113 gene has two neighbors on either side on the negative strand: OTOF otoferlin preceding and HADHA hydroxyacyl-CoA following. Directly opposite the GPR113 on the positive strand is the EPT1 gene.
The GPR113 gene is
.
The protein product of GPR113 gene is a G-protein coupled receptor. The protein has three transcript variants in humans. Of these three, GPR113 Variant 1 has the longest amino acid sequence, and has the highest identity to orthologs. This leads to the conclusion that GPR113 Variant 1 is the homo sapiens descendant of the ancestral GPR113 gene. GPR113 Var 1 contains 1079 Amino Acids, and is integral to the plasma membrane. The 7-pass receptor contains 4 domains highlighted in the figure at right: Signal Peptide (Red