Grignard reaction [SEP] named after
Grignard reaction
The Grignard reaction (pronounced ) is an organometallic chemical reaction in which alkyl, vinyl, or aryl-magnesium halides (Grignard reagent) add to a carbonyl group in an aldehyde or ketone. This reaction is important for the formation of carbon–carbon bonds. The reaction of an organic halide with magnesium is "not" a Grignard reaction, but provides a Grignard reagent.
Grignard reactions and reagents were discovered by and are named after the French chemist François Auguste Victor Grignard (University of Nancy, France
. The product is known as a Grignard Reagent. Named after him, this organo-magnesium compound (R-MgX) (R = alkyl ; X = Halogen) readily reacts with ketones, aldehydes, and alkenes to produce their respective alcohols in impressive yields. Grignard had discovered the synthetic reaction which now bears his name (the Grignard reaction) in 1900. In 1901, Grignard published his doctoral thesis titled "Thèses sur les combinaisons organomagnesiennes mixtes et leur application à des synthèses d‘acides, d‘alcools et d‘hydrocarbures". He