OCA2 [SEP] found in taxon
OCA2
P protein, also known as melanocyte-specific transporter protein or pink-eyed dilution protein homolog, is a protein that in humans is encoded by the oculocutaneous albinism II (OCA2) gene. The P protein is believed to be an integral membrane protein involved in small molecule transport, specifically of tyrosine - a precursor of melanin. Certain mutations in OCA2 result in type 2 oculocutaneous albinism. OCA2 encodes the human homologue of the mouse p (pink-eyed dilution) gene.
The human OCA2 gene is located
-Europeans mixed with "Scandinavian hunter-gatherer" women who carried genetic alleles HERC2/OCA2, which causes a combination of blue eyes and blond hair. Proto-Indo-Iranians who split from Corded Ware culture formed the Andronovo culture and are believed to have spread genetic alleles HERC2/OCA2 that cause blond hair to parts of West Asia, Central Asia and South Asia. Genetic analysis in 2014 also found that people of the Afanasevo culture which flourished in the Altai Mountains were genetically identical to Yamnaya Proto-Indo-Europeans