Cyclic nucleotide-gated channel alpha 1 [SEP] found in taxon
Cyclic nucleotide-gated channel alpha 1
Cyclic nucleotide-gated channel alpha 1, also known as CNGA1, is a human gene encoding an ion channel protein. Heterologously expressed CNGA1 can form a functional channel that is permeable to calcium. In rod photoreceptors, however, CNGA1 forms a heterotetramer with CNGB1 in a 3:1 ratio. The addition of the CNGB1 channel imparts altered properties including more rapid channel kinetics and greater cAMP-activated current. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/B1 channels
terminal.
Structure Alpha subunits.
Cyclic nucleotide gated channel alpha-subunits include 
- Cyclic nucleotide-gated channel alpha 1
- Cyclic nucleotide-gated channel alpha 2
- Cyclic nucleotide-gated channel alpha 3
- Cyclic nucleotide-gated channel alpha 4
Structure Beta subunits.
Cyclic nucleotide gated channel beta-subunits include:
- Cyclic nucleotide-gated channel beta 1
- Cyclic nucleotide-gated channel beta 3
Structure Pore.
The structure of the pore is similar to other ion channels that contain