Augustus d'Este [SEP] cause of death
’s marriage had been null and void. Although he had affairs with women, he never married and, therefore, even if he had succeeded to his father's titles, they would have become extinct on his own death.
Illness.
Augustus d'Este is the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made. The course of his MS, which was not diagnosed during his lifetime, is known from the diaries he kept. D'Este left a detailed diary describing his 22 years living with
the Russell ministry in 1852.
Family.
Lord Truro married firstly Mary, widow of William Devaynes (1730–1809) and daughter of William Wileman, in 1813. They had three surviving children. After Mary's death in 1840 he married secondly Mademoiselle d'Este, Augusta Emma d'Este, daughter of Prince Augustus Frederick, Duke of Sussex and a first cousin of Queen Victoria, on 13 August 1845. There were no children from this marriage. Lord Truro died in London in November 1855, aged 76, and was succeeded in