EID2 [SEP] found in taxon
EID2
EP300 interacting inhibitor of differentiation 2, also known as EID2 is a human gene.
Function.
The protein encoded by this gene may function as an endogenous suppressor of TGF-beta signaling and inhibits differentiation by blocking the histone acetyltransferase activity of p300, class I histone deacetylase, HDACs. The N-terminal portion of EID-2 was required for the binding to HDACs. This region was also involved in the transcriptional repression and nuclear localization, suggesting the importance of the involvement of HDACs in the EID-2 function. EID-2
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- J. Lanjouw: "Ivan Murray Johnston (1898–1960)." In: "Taxon", Vol. 9, Nr. 7 (Sep., 1960), Seite 220
- Robert Jan 'Roy' van de Hoek: "Restoration and Recovery for Elna Bakker and Ivan Johnston. "R&R" for the Playa del Rey Frogs and Plants." 2005