Carbonic anhydrase II [SEP] found in taxon
Carbonic anhydrase II
Carbonic anhydrase II (gene name CA2), is one of sixteen forms of human α carbonic anhydrases . Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. 
Renal carbonic anhydrase allows the reabsorption of bicarbonate ions in the proximal tubule.
Interactions.
Carbonic anhydrase II has been shown to interact with band 3 and sodium-hydrogen antiporter 1.
Brinzolamide
Brinzolamide (trade names Azopt, Alcon Laboratories, Befardin, Fardi Medicals, ) is a carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Chemistry.
Brinzolamide is a carbonic anhydrase inhibitor (specifically, carbonic anhydrase II). Carbonic anhydrase is found primarily in erythrocytes (but also in other tissues including the eye). It exists as a number of isoenzymes, the most active of which is carbonic anhydrase II (CA-II).
Indications.