KIAA1797 [SEP] found in taxon
of 6117 base pairs.
Gene Expression.
KIAA1797 was determined to express ubiquitously at varying levels throughout the human body. Based on the EST profile of Unigene, KIAA1797 expression have been observed in tissues ranging from reproductive to secretory.
mRNA.
Predicted secondary mRNA structures in the 5'UTR and the 3'UTR are “ugagaugaacucgguaucuca” and “uccuaagagaggag” respectively. Other possible secondary structures are shown in the table below.
Protein sequence.
The main isoform of the human protein is 1801 amino acid long, a total of
200,072 Da.
Two distinct Domain of unknown function(DUF) are found in the sequence.DUF3730 (465-682aa) appears two times in the sequence; this domain family is found in eukaryotes and is typically between 220 and 262 amino acids in length. DUF3028(1213-1801aa). No additional information was provided regarding this DUF.
Homology.
KIAA1797 is well conserved in mammals. However, it is also found in non-mammalians with lower sequence identities.
Gene Neighborhood.
KIAA1797 is downstream of MLLT3 and