KIAA0922 [SEP] chromosome
human genome at chromosomal location 4q31.3 on the plus strand and is 170,364 base pairs (bp) in length, spanning from 154,387,498 to 154,557,863 along chromosome 4 (NC_000004.11). The gene has the aliases TMEM131L, FLJ10592, DKFZp586H1322, and LOC23240 The gene includes 44 distinct introns (with an additional 6 probable non-overlapping alternative last exons). The function of this gene is not yet fully understood.
The gene includes the Domain of unknown function 3651 (DUF3651) which is part of the transmembrane associated family pfam12371 and
KIAA0922
Transmembrane protein 131-like(TMEM131L protein), alternatively named uncharacterized protein KIAA0922 (KIAA0922 protein), is an integral transmembrane protein encoded by the human gene KIAA0922 that is significantly conserved in eukaryotes, at least through protists. Although the function of this gene is not yet fully elucidated, initial microarray evidence suggests that it may be involved in immune responses. Furthermore, its paralog, prolyl endopeptidase (PREP) whose function is known, provides clues as to the function of TMEM131L.
Gene.
The KIAA0922 gene is found in the