FABP7 [SEP] found in taxon
FABP7
Fatty acid binding protein 7, brain (FABP7; also brain lipid binding protein, BLBP), is a human gene.
Function.
The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism.
FABP7 is expressed, during development, in radial
, with seven SNPs, a positive result. The effect of the gene in the latter study was stronger in males. This study also linked FABP7 variation to weak prepulse inhibition in mice; deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives.
External links.
- Schizophrenia, Startled Response & Fabp7: Future Dietary Changes for At-Risk Mothers? Schizophrenia Daily News Blog, 2007-11-07
- Gross L (2007) A Candidate Gene for a Biological Marker of Schizophrenia in