Histone H3 [SEP] found in taxon
are denoted as Histone H3.1, Histone H3.2, Histone H3.3, Histone H3.4 (H3T), Histone H3.5, Histone H3.X and Histone H3.Y but have highly conserved sequences differing only by a few amino acids. Histone H3.3 has been found to play an important role in maintaining genome integrity during mammalian development. Histone variants from different organisms, their classification and variant specific features can be found in "HistoneDB - with Variants" database.
Genetics.
Histone H3s are coded by several genes in the human genome, including:
and three species in the allied genus "Lambis". The cladogram was based on DNA sequences of both nuclear histone H3 and mitochondrial cytochrome-c oxidase I protein-coding gene regions. In this proposed phylogeny, "Strombus galeatus" is show as a sister taxon to the clade that includes "Lobatus gallus" ("Strombus gallus"), "Lobatus gigas" ("Strombus gigas"), "Lobatus costatus" ("Strombus costatus"), "Lobatus raninus" ("Strombus raninus"),