Enteropeptidase [SEP] found in taxon
Enteropeptidase
Enteropeptidase (also called enterokinase) is an enzyme produced by cells of the duodenum and is involved in digestion in humans and other animals. Enteropeptidase converts trypsinogen (a zymogen) into its active form trypsin, resulting in the subsequent activation of pancreatic digestive enzymes. Absence of enteropeptidase results in intestinal digestion impairment.
Enteropeptidase is a serine protease () consisting of a disulfide-linked heavy-chain of 82-140 kDa that anchors enterokinase in the intestinal brush border membrane and a light-chain of 35–62 kDa that
The structure contains a six stranded beta-sheet and one alpha-helix.
Examples.
The speract receptor found in egg, is a transmembrane glycoprotein. Other members of this family include the macrophage scavenger receptor type I, an enteropeptidase, and T-cell surface glycoprotein CD5.