Glutaryl-CoA dehydrogenase [SEP] chromosome
Glutaryl-CoA dehydrogenase
Glutaryl-CoA dehydrogenase (GCDH) is an enzyme encoded by the GCDH gene on chromosome 19. The protein belongs to the acyl-CoA dehydrogenase family (ACD). It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and carbon dioxide in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this
Glutaryl-CoA dehydrogenase (non-decarboxylating)
Glutaryl-CoA dehydrogenase (non-decarboxylating) (, "GDHDes", "nondecarboxylating glutaryl-coenzyme A dehydrogenase", "nondecarboxylating glutaconyl-coenzyme A-forming GDH") is an enzyme with systematic name "glutaryl-CoA:acceptor 2,3-oxidoreductase (non-decarboxylating)". This enzyme catalyses the following chemical reaction
The enzyme contains FAD.