FAM83A [SEP] chromosome
FAM83A
Protein FAM83A (family member with sequence similarity 83) also known as tumor antigen BJ-TSA-9 is a protein that in humans is encoded by the FAM83A gene.
This protein is predicted to contain one domain of unknown function 1669 (DUF1669), which places this protein into the PLDc_SuperFamily. It has been linked to be a potential biomarker in lung, prostate, and bladder cancers.
Gene.
FAM83A is located on chromosome 8, locus q24.13, and spans 27,566 base pairs. There is a promoter
approximately 4,000 base pairs upstream as predicted by the tool ElDorado by Genomatix. Deletions in this part of the chromosome, including the FAM83A gene, often result in Langer-Giedion syndrome.
mRNA.
The FAM83A mRNA has 10 different splice forms, with transcript variant 1 being the subject of this article. This mRNA consists of approximately 2,900 base pairs. It contains a domain of unknown function 1669 (DUF1669), and is a member of the PLDc_SF superfamily. It has been placed into this superfamily based on highly similar