TMEM 249 [SEP] chromosome
TMEM249
TMEM 249 is a protein that in humans is encoded by the C8orfk29 gene.
Locus.
TMEM 249 is located near the end of the long arm of chromosome 8 in humans.
Common aliases.
TMEM 249 is also known as C8orfk29.
Primary sequence & variants/isoforms.
The primary sequence found at NCBI and
Aceview on NCBI predicts there are five spliceforms, with four closely resembling one another and the fifth missing a large 5' intron region. Softberry reinforces the Aceview data by
and 2 are translated in the 3' to 5' direction while transcripts 3 through 5 are translated in the 5' to 3' direction. Note that the gene is encoded on the minus strand within the chromosome.
Paralogs.
The only known paralog of human TMEM 249 is found in the second isoform of the protein in Gorillas. Of the 217 amino acids aligned between gorilla and human TMEM 249, 96% are in complete consensus and 99% are conserved.
Orthologs.
TMEM 249 orthologs includes all