FAM46C [SEP] found in taxon
survival in Myeloma patients.
Gene.
"Homo sapiens" FAM46C spans 22,456 bases on chromosome 1. Microarray data suggests that human FAM46C displays elevated expression levels in bone marrow, CD71+ early erythroid, various B-cells, T-cells, and lymphocytes, as well as all tissues associated with testes.
Evolution and homology.
"Homo sapiens" FAM46C is highly conserved in close orthologs with only small changes in protein AA sequence when comparing to other mammals.
FAM46C and specifically the DUF1693 is traceable
Xenopus tropicalis", and "Mus musculus". A strict ortholog of FAM46B is not found in reptiles or birds; however both the FAM46A and the FAM46C paralogs are found in the Anolis carolinensis, and the FAM46C paralog is found in birds such as Gallus gallus.
Homology Distant homologs.
Distant homologs of "FAM46B" are present in "Drosophila" and nematodes such as "Caenorhabditis elegans". There are no orthologs of FAM46B in plants, protists, or fungi.
Homology Phylogeny.
The phylogenetic tree of "