S100A1 [SEP] found in taxon
. S-Nitrosylation of S100A1 at Cys85 reorganizes the conformation of S100A1 at the C-terminal helix and the linker connecting the two EF hand domains.
The most accurate high-resolution solution structure of human apo-S100A1 protein (PDB accession code: 2L0P) has been determined by means of NMR spectroscopy in 2011.
S100 genes include at least 19 members which are located as a cluster on chromosome 1q21.
Function.
S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells,
S100 protein
The S100 proteins are a family of low-molecular-weight proteins found in vertebrates and characterized by two calcium-binding sites that have helix-loop-helix ("EF-hand type") conformation. There are at least 21 different S100 proteins. They are encoded by a family of genes whose symbols use the "S100" prefix, for example, "S100A1", "S100A2", "S100A3".
They are also considered as Damage-associated molecular pattern molecules (DAMPs)