FAM214A [SEP] chromosome
segregation during meiosis.
Gene.
Gene Overview.
The "FAM214A" gene is located on the negative DNA strand (see Sense (molecular biology)) of chromosome 15 between position 52,873,514 and 53,002,014; thus making the gene 97,303 base pairs (bp) long. "FAM214A" has been previously labeled with two other aliases, known as KIAA1370 and FLJ10980. The "FAM214A" gene is predicted to contain 12 exons which comprise the final 4231 bp mRNA transcript after transcription has occurred. It is this mRNA product that
able to predict approximately 10 percent of the protein's structure with 95 percent significance. The diagram for this is shown to the left.
Conservation.
Conservation Paralog.
A single paralogous gene has been found on chromosome 9 in Homo sapiens and is named "FAM214B" (family with sequence similarity, B). FAM214B, although considered a paralog, has a significantly different protein sequence from that of FAM214A. When the two were compared against each other on NCBI’s BLAST, the only significant similarity observed was within the last