Alfonsina Orsini [SEP] place of death
Alfonsina Orsini
Alfonsina Orsini (1472 – 1520) was a Regent of Florence. She governed the Republic of Florence during the absences of her son in the period of 1515–1519. Her rule was feared as a sign of the end of republican government there. She was born from a noble family and raised in the royal court of Naples. She was the spouse of Piero di Lorenzo de' Medici from 1488 and the mother of Lorenzo II de' Medici. She helped restore the Medicis to power after they had been exiled
of puerperal fever or plague, and Lorenzo died on 4 May, his title over Urbino reverting to Francesco Maria I della Rovere. King Francis wanted Catherine to be raised at the French court, but Pope Leo had other plans for her.
Catherine was first cared for by her paternal grandmother, Alfonsina Orsini (wife of Piero de' Medici). After Alfonsina's death in 1520, Catherine joined her cousins and was raised by her aunt, Clarice de' Medici. The death of Pope Leo in 1521 briefly interrupted