CNGB1 [SEP] found in taxon
CNGB1
Cyclic nucleotide gated channel beta 1, also known as CNGB1, is a human gene encoding an ion channel protein.
See also.
- Cyclic nucleotide-gated ion channel
External links.
- GeneReviews/NCBI/NIH/UW entry on Retinitis Pigmentosa Overview
the rod channel. Unlike CNGA1, CNGB1 subunits expressed alone do not produce functional CNG channels, but coexpression of CNGA1 and CNGB1 subunits produces heteromeric channels with modulation, permeation, pharmacology, and cyclic-nucleotide specificity comparable to that of native channels.
CNG channels form tetramers, and recent studies indicate that native rod channels consist of three CNGA1 subunits and one CNGB1 subunit. CNGA3 subunits, previously called the cone α subunits, form functional channels when its expression occurs exogenously. On the other hand, CNGB3, previously called the