Participation of urea and liver arginase in the thermoregulation processes during endotoxin fever
Dynamics of heat exchange processes during endotoxin fever in rats and rabbits and their staging depends on the liver arginase activity, the L-arginine-NO-system state and the blood urea level that determine their direction and intensity. Apparently, the L-arginine participation in the urea cycle and its active use in the urea formation processes during endo-toxinemia play a significant role in the mechanisms of regulation of the L-arginine-NO-system activity, thermoregulation and endogenic antipyresis.