Modern Diagnostics of Intrauterine Infections and the Following Quality of the Child’s Life
Introduction. Nowadays congenital infections are widespread pathology among children. Congenital infections are established a lot of stillbirth, neonatal and infantile mortality. Purpose. To develop and introduce the step algorithm of the diagnostic of realization of congenital infection with clinical estimation of newborn’s health status from risk group taking into account pathomorphological changes of placenta-cord complex for the estimation of unfavorable influence of the infection. Materials and methods. The analysis of neonatal period of 247 newborns is given in this article. We’ve done the estimation of their health status using anthropometric, general clinical and instrumental methods of the investigation. Results. It have been established that physical development in children with clinical manifestation of congenital infections and in children with high or moderate risk of the development of congenital infections are statistically lower in comparison with healthy children and children with low risk. The diagnosis of congenital infections was confirmed by estimation of the acute phase proteins, polymerase chain reaction and data of placenta-cord complex. The criteria of the obligatory and delayed administration of antibiotic therapy were set. Conclusions. Mandatory and delayed criteria of the administration of antibiotic therapy will rationally rehabilitate children and reduce the number of cases of unjustified assignment of antibacterial therapy.