THE CHANGE IN THE INCIDENCE OF SOME HERPES VIRUS INFECTIONS IN POPULATIONS WITH A HIGH PREVALENCE OF HIV INFECTION
Objective: to characterize the structure and dynamics of the incidence of herpes virus infections (recorded in statistical forms) in a region with a high prevalence of HIV infection. Materials and methods. The state medical statistics for the Irkutsk region for the first 20 years after the start of the spread of HIV infection (2002-2017) was used as the material for the study. At the first stage, a retrospective analysis of the incidence of herpes virus infections was performed. The long-term incidence of herpes virus infections among children, adolescents and adults was compared with the prevalence of HIV infection in the population with the calculation of the Spearman correlation. At the second stage, a cohort study was conducted. The incidence rates of cytomegalovirus infection were compared in a cohort of patients with HIV infection and among the rest of the population. Relative risks of cytomegalovirus infection detection were assessed over the years 2008 and 2015. Conclusion. By 2017, the prevalence of HIV infection in the general population reached 1,7%. There was a direct strong correlation (0,7-0,8) between the prevalence of HIV infection and the incidence of chickenpox, infectious mononucleosis and cytomegalovirus infection. Starting in 2007, incidence of herpes virus infections was increased among children as well as among adults. In 2008-2015 the relative risk of cytomegalovirus infection in a cohort of HIV patients increased from 70,1 to 130,3. The incidence of herpes simplex among HIV patients was also increased.