SPECIAL FEATURES OF TAXONOMIC STRUCTURE AND ANTIBIOTIC RESISTANCE OF MICROFLORA ISOLATED FROM PATIENTS IN MULTIFIELD SURGICAL HOSPITAL
Objective. The objective of work was to study special features of microflora isolated from patients in multifield surgical hospital within the period from 2010 to 2015 years and to evaluate its resistance to antibacterial drugs. Materials and Methods. Microbiological study of 13896 samples of clinical material obtained from 4569 hospital patients was carried out. Isolation, identification and determination of susceptibility to antibiotics were performed by conventional methods using microbiological analyzers. Results. It was found that taxonomic structure of microflora has changed during the six-year period of studies, being characterized by the increased frequency of isolation of gram-negative strains A. baumanii, K. pneumoniae and E. coli alongside the decreased fraction of P. aeruginosa and S. aureus. Increase in resistance of the main microorganism species was revealed to the majority of antibacterial drugs used in the hospital. “Problem” microorganisms showing the highest antibiotic resistance with the tendency towards growth include A. baumanii and K. pneumoniae. Conclusions. The obtained data allow to optimize the empiric therapy in multifield surgical hospital and should be considered when developing system of microbiological monitoring of nosocomial infections.