LEVEL OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE IN THE BLOOD SERUM OF HEALTHY INDIVIDUALS AND PATIENTS WITH OSTEOARTHRITIS
The article discusses the problem of osteoarthritis (OA) as part of systemic inflammation. Correlation between the development of systemic inflammation and pro-inflammatory cytokines produced by white adipose tissue is shown. There are some literature data on the role of nicotinamide phosphoribosyltransferase (Nampt) in the development of OA. The level of Nampt in the serum of healthy subjects and in patients with OA is studied. Correlation between an increased level of Nampt and clinical signs of OA is shown.