PROBLEM DIAGNOSIS AND TREATMENT OF HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA PATIENTS WITH CORONARY HEART DISEASE
In this paper, one of the possible causes of high LDL-C levels in patients with a coronary heart disease will be discussed. Such a reason may be heterozygous familial hypercholesterolemia (HeFH). It is considered to be a heterozygous form, as it occurs in adulthood, that is, when patients go to the doctor with complaints on the part of the cardiovascular system. The relevance of this pathology detection boils down to which is called heterozygous hypercholesterolemia, that can flow under the mask nonspecific increase of LDL-C. The survey shows the problem of underdiagnosis HeFH at which increases the risk of cardiovascular complications, this is currently standing at first place to be one of the first causes for death in the Russian Federation. The data on the etiology, pathogenesis, epidemiology and clinical manifestations HeFH. Considered the Dutch (Dutch Lipid Clinic Network) and British (Simon Broom Registry) diagnostic criteria for suspected HeFH already in the primary treatment of the patient to the doctor. The problem of HeFH pathology consists in the fact that a full diagnosis based on genetic studies in our country is difficult, and modern treatments for HeFH are considered expensive and are not included to be registered of high-tech medical care.