Displays of Vascular Complications while Experimental Diabetes Mellitus and Possible Ways of Their Correction.
The oxidazing stress while experimental diabetes mellitus is accompanied by deficiency of nitric oxide, apparently, owing to its inactivation while interaction with superoxide anion radical (О2-) with the formation ofperoxinitrate - reactionary ability of the molecule, causing the damage of an endothelium of vessels of microcirculation channel, a mutation of various genes and apoptosis. Ubichinon compositum, suppressing the LPO, promotes concentration of nitric oxide. Negative strong correlation was revealed among these indices (r=-0,60, р=0,05). Dilatation of vessels of microcirculation channel is carried on and it shows the decrease of vascular resistance (Pi) and elastic properies of a vascular wall.