PULMONARY AND GENERALIZED FORMS OF MYCOBACTERIOSIS IN HIV INFECTION IN THE MORPHOLOGICAL ASPECT
Etiological role of M. avium-intracellulare was studied on the material of 13 cases of deaths from HIV infection at AIDS stage, basing on the life-time bacteriological examination results. Grave caseous necrotic changes were found in the lymph nodes, lungs and other organs with large number of mycobacteria M. avium-intracellulare, detected in bacteriological and bacterioscopic, including immunohistochemical examinations. Singularity of anatomicopathological presentation allowed to consider mycobacteriosis, developing in HIV infection at AIDS stage, in the same pathogenetic aspect, as primary tuberculosis. General similarity of morphological manifestations of mycobacteriosis in our study with primary tuberculosis took place due to, obviously, not only the genetic relatedness of these diseases pathogens, their similar pathogenic properties, but also the state of the patients immunity, playing a cardinal role in morphogenesis and determining the form of the disease.