The use of immunomodulators in the treatment of patients with pyo-necrotic forms of diabetic foot
Based on the results of examination and treatment of 103 patients with pyo-necrotic forms of diabetic foot defined the disorders of the immune status and the ways of their correction in such patients. The inclusion of immunomodulators in the treatment program led to positive changes in the indicators characterizing the state of the immune system, reduce complications, the frequency of "high" amputation and shortening of treatment. Clinical signs of secondary immune deficiency in patients with purulent-necrotic forms of diabetic foot accompanied by changes in laboratory immunological parameters: the presence of relative and absolute lymphopenia, decrease in relative and absolute number of T-lymphocyte subpopulation of CD4 + lymphocytes, phagocytosis rates.