FREE OLIGOSACCHARIDES IN BLOOD PLASMA OF PATIENTS WITH POLYCYTHAEMIA VERA: GENERAL PROFILE CHARACTERISTICS
In this work for the first time the chromatographic spectra of plasma free oligosaccharides of patients with polycythaemia vera (erythremia) were obtained and compared with those of practically healthy donors. The glycans were separated with normal phase high-performance liquid chromatography. The plasma samples of the patients were found to have a significant increase in the concentration of oligosaccharides consisting of 7-9 monosaccharides or appearance of new species of these structures. In addition, some new minor components were revealed.