Oxidative destruction of active pharmaceutical substances under combined UV-radiation and hydrogen peroxide
In order to develop effective methods for deep purification of wastewater of pharmaceutical enterprises, the processes of oxidative destruction of model solutions of active pharmaceutical substances (APS) (for example, acetylsalicylic acid (ASA), tetracycline, sulfadimezine) under individual exposure to ultraviolet radiation, hydrogen peroxide and their combined action were studied. It has been established that the degree of oxidative degradation reaches 95-99% with joint exposure of UV/ Н2О2. It is proved that the initial concentrations of APS and reagents have a significant effect on the degree and speed of the oxidation process. At the qualitative and quantitative level, products of oxidative degradation of APS are identified. The electron absorption spectra before and after the oxidative degradation of APS are presenyed. A concLusion about the appLicability of the described oxidative methods for the effective destruction of the investigated pharmaceutical preparations was made.