Influence of the Social Environment on the Incidence and course of Vaccination process in children from orphanages
The data of current vaccination process in 83 children living in Orphanages with various forms of social organization of children. Neurological pathology was diagnosed in 45 children, with Down’s syndrome in 18 children. The comparison group consisted of 20 children without Neurological pathology and Down syndrome. All the children were vaccinated. Complete acellular vaccines (DTP/ Infanriks) had 56 children (67.5%). To prevent measles used divaccine and Priorix vaccine (n = 70). The levele of intercurrent diseases was decrease in Orphanage № 13 (the family type of Orphanage). The number of cases in Orphanag № 12 per 1 child was 5.89 ± 0.67 compared to 3.5 ± 0.47 in Orphanag № 13 (P < 0.05). The post-vaccination period in 61.5% cases of Orphanage № 13 are asymptomatic (in the Orphanage № 12 in 46.2% of cases). The neurological pathology is characterized a greater percentage of post-vaccination reactions. The antibody titers seronegative to diphtheria was not identified. The number of seronegative antibodies on measles consisted of 10 children (including 8 children neurological groups) and to mumps - 16 children, all of neurological groups, no significant differences in Orphanage. Children with neurological disorders who live in children 's homes, you need to determine antibody titers two months after vaccination against measles and mumps to decide on supplementary immunization.