THE MODULATING EFFECT OF BIOLOGICALLY ACTIVE SUBSTANCES ON ESCHERICHIA COLI
Objective: the aim of the study was to study the effects of amino acids (taurine, arginine) and invitro zinc aspartate on Escherichia coli growth and sensitivity to antibiotics (amoxiclav and ofloxacin). Material and methods. The object of study is a non-pathogenic strain of Escherichia coli. The subject of the study is the modulating effect of taurine, arginine, zinc aspartate. Results. Taurine, arginine and zinc aspartate in certain concentrations inhibit the growth of Escherichia coli, and also in certain concentrations have a modulating effect on the sensitivity of Escherichia coli to antibacterial substances. Conclusions. The established patterns can be used as a theoretical basis for the development of new antibacterial drugs, used primarily for the treatment of intestinal infections. And also for understanding the spectrum of the use of biologically active substances for medical purposes.