TECHNOLOGY OF PROCESSING VEGETABLE RAW MATERIAL IN A THERAPEUTIC BIOLOGICAL ACTIVE NATURAL COMPLEX OF MEDICINAL AND PREVENTIVE DETERMENATION
The article deals with the technology of production of the encapsulated form of a new specialized product containing a biologically active natural complex of extracts of medicinal plants: Echinacea Purpurea and licorice root. Pharmacological characteristics of the active principles of prescription components proved the functional orientation of the specialized product and its synergistic properties in relation to metabolic support of the immune system. The quantitative composition was chosen according to the regulation of the composition of standard prescriptions approved by the State pharmacological Committee. An innovative technology of the encapsulated form of biologically active additives in the form of biologically active natural complex containing: mg/1 capsule weighing 0.6 g: Echinacea purple extract - 60, at least - 1.5; ascorbic acid - 60; rutin - 30; licorice root extract - 20; zinc citrate - 13.4; sodium Selenite 0.014. The adjustable technological parameters of production, ensuring the preservation of biologically active components of the formulation and their functional properties were determined experimentally. The developed technology includes the following main stages of production: preparation of raw materials, preparation of semi-product 1 and semi-product 2, preparation of a mixture for encapsulation, encapsulation and dust control, obtaining liquid extraction, thickening of the liquid extract, obtaining a dry extract by spray drying. Gelatin capsules combine the prescription ingredients, protect the contents from the effects of adverse environmental factors, provide the necessary speed of delivery of biologically active components to the target cell and localization of action. Regulated indicators of nutritional value are established. The effectiveness and functional orientation of the developed product have been proven in clinical studies in comparison with drug therapy of the upper airways with the provision of anti-inflammatory, adaptogenic and immunomodulatory effects.