BIOLOGICAL ACTIVITY AND ANALYSIS MASS SPECTRAL DECAY TRIFLUOROMETHYL PYRROLOQUINOLONES
Tests have been conducted to the biological activity of trifluoromethyl derivatives of pyrrolo quinolones series. Preliminary results of the antimicrobial action of some trifluoromethyl pyrrolo quinolones. The studied fluoro pyrrolo quinolones have a sufficiently broad spectrum of activity as against test strains and clinical strains of microorganisms. The report provides analysis of the mass-spectral decay previously received by us different articulated with different substituents of the compounds for accurate evidence of their structure. From the analysis of the mass spectral decay variously articulated trifluoro pyrrolo quinolones it follows that they behave as poly-methylated indoles. In the case of the presence in the molecule methoxy group, peri-substituents in the pyrrolo [3,2-h] quinolones a significant contribution to the scheme of mass-spectral decay make these substituents. Detailed mass-spectrums trifluoro pyrrolo quinolones received on the mass spectrometer FINNIGAN MAT. INCOS-50 with the direct input of the sample into the ion source when the ionization energy of 70 eV.