THE DYNAMICS OF <i>T</i> AND <i>B</i> LYMPHOCYTES INDICES IN PATIENTS WITH MDR TUBERCULOSIS UNDER THE INFLUENCE OF IMMUNOMODULATORS
The dynamics of T and B lymphocytes indicators in patients with c MDR tuberculosis under the influence of immunomodulators. The study included 93 patients with MDR tuberculosis and they were divided in 3 groups comparable in diagnosis and disease severity: the first group, control, included 31 patients who received the antituberculosis treatment; 2 experimental group included 31 patients who received the drug Mellozan; 3 experimental group included 31 patients who received the drug Bior in combination with anti-TB treatment. We studied the drug influence on the dynamics of T and B lymphocytes in patients. The indices of content and functional activity of T lymphocytes before the treatment were decreased, while, the indices of content and the functional activity of B lymphocytes before the treatment were increased. The inclusion of the drug BioR or Mellozan in complex treatment regimen has a positive effect on the dynamics of T and B lymphocytes indices in patients with MDR forms of pulmonary tuberculosis by immunomodulatory and detoxifying action of the drugs.