THE STUDY OF ANTIBIOTIC- AND FAGOSENSITIVITY OF NOSOCOMIAL STRAINS BACTERIA ISOLATED FROM TRANSPLANTED PATIENTS
Antibiotic and fagosensitivity most etiologically important nosocomial strains of bacteria - Pseudomonas aeruginosa, Klebsiella pneumoniae, E. coli, Proteus spp., Staphylococcus spp. were studied. Multiple drug-resistant bacteria as gram-positive and gram-negative, isolated from 8 substrates, had been demonstrated. With regard to the sensitivity of Pseudomonas aeruginosa >40% was observed in 40-50% of the strains to aminoglycosides -aztreonam, amikacin, netilmicin, and only 23-25% of the strains - to gentamicin and levofloxacin (an average of antibiotic susceptibility was 27%). All strains of ESBL Klebsiella drew up and were sensitive only to imipenem, meropenem and aminoglycosides. Specific phages lysed 43-48% of the strains Pseudomonas aeruginosa and Klebsiella pneumoniae, E. coli, Proteus spp., multidrug resistant strains of Staphylococcus spp. It is proposed to introduce the use of phages in clinical practice.