Syndrome of endogenous intoxication in regular active smokers
We have analyzed the relationship of features smoking status and the presence and severity of endogenous intoxication in regular active smokers. We take into account parameters such as smoking status experience of smoking, smoking intensity, index pack / years, the type of smoking behavior, the degree of nicotine dependence, level of motivation to quit smoking. In addition, the study was conducted levels of anxiety and depression and quality of life assessment. All patients of the study group and the control group were examined in the Health Center. We have found that a regular active smokers showed a statistically significant intensification of catabolic processes in the blood plasma, which manifests an increase total pool of low and medium molecular weight blood plasma, preferential accumulation of these substances in the plasma compared with glycocalyx erythrocytes, moreover increased excretion these substances in the urine. It was found that expression of endogenous intoxication has a statistically significant direct correlation with the experience and intensity of smoking parameters of bronchial obstruction and lung spirographic age, the presence of myocardial hypoxia, impaired psycho-emotional status, and negative correlation with the parameters of the physical, role and social functioning.