Prognostication of the level of pressure in the pulmonary artery at patients with bronchial asthma
By means of the multiple regression analysis we have created a model of prognostication of the level of pressure in the pulmonary artery at patients with bronchial asthma. We have estimated the prognostic importance of a number of clinical factors (age, sex, smoking, severity and duration of the disease) and laboratory indicators (TBK-active products level, carbonyl derivatives, uric acid, plasma homocysteine, superoxide dismutase activity) in 276 patients with bronchial asthma. It was found that the age of a patient, the level of carbonyl derivatives and activity of superoxide dismutase in blood serum are of greatest value for the prognostication of pulmonary hypertension. Using the regression equation, it is possible to predict pressure level in the pulmonary artery with an accuracy of 1-5 mm of mercury.