Interrelation of polymorphism of SLC6A4 and MAOA genes of the serotonic system with human physical performance
Human physical performance is determined by environmental (physical training, nutrition, etc.) and genetic factors. Various features of the higher nervous system plays an important role in the realization of sport perfomance. The serotonergic system is a key neurotransmitter system of the body that modulates and coordinates the action of other neurotransmitter systems. Polymorphism of protein coding genes of this system significantly affects its functioning. In this article we have shown that 5HTTLPR polymorphism of serotonin transporter gene (SLC6A4) and uVNTR polymorphism of monoamine oxidase A gene (MAOA) have an impact on the predisposition for sport among men.