EXPERIMENTAL MODELING OF VARIOUS DEGREE OF ALCOHOL INTOXICATION IN RATS
Currently, there is a large number of publications describing the experimental study of pathological changes in the body of laboratory animals under the influence of alcohol intoxication usually of severe state up to coma. Herewith, there are not many studies describing medium and mild intoxication. The aim of the study was experimental modeling of alcohol intoxication of varying severity on laboratory rats. To perform intoxication of various severity the control group three test groups of rats were formed. The status of all the animals was evaluated by a score system to assess intoxication using open field test. Gas chromatography was applied to determine the amount of alcohol in blood. Based on these data we managed to allocate mild, moderate and severe alcohol intoxication in laboratory rats.