ECOLOGICAL STRESS AS A FACTOR INFLUENCING HORMONE-METABOLIC CHARACTERISTICS OF BLOOD SERUM OF MEN
Hormone-metabolic characteristics of the blood serum are investigated in 518 donor men aged 20-34 years who has lived in 6 districts of Novosibirsk at least for 10 years, including 3 ecologically problem districts. The radioimmunoassay was used to determine hormones of the hypophysial-thyroid-adrenal system, such as adrenocorticotropin, somatotrophic hormone, Cortisol, and triiodothyronine; the biochemical methods calculated crude protein, total cholesterol, and glucose. Reliable differences in the characteristics under study with respect to the area of living are obtained using statistical Wilkinson-Mann-Whitney analysis. The reliable influence of ecological stress on the characteristics under study with respect to the area of living evidences the syndrome of ecological stress, i.e. ecologically dependent stress that is formed when a man lives in the ecologically problem area for a long time. The intensity of changes in hormone-metabolic characteristics directly depends on ecological living conditions, which should be considered in the prognosis, diagnostics and detecting people with risk factors.