Adaptation abnormalities in posttraumatic stress disorder corrected by low dose heparin injections in an experiment
The reproducibility of the model of post-traumatic stress disorder was confirmed using new methods of testing and recording behavioral events, assessing the serum corticosterone levels and analyzing the state of the stomach bottom wall in male Wistar rats. It was shown that the course of administration of low dose heparin (64 IU / kg) after 10-day exposure to predator-induced stress (fear of predator) had a therapeutic effect increasing the adaptive capacity of the organism and resulting in the psychosomatic recovery.