Morphofunctional bases of the encephalopathy formation at perinatal hypoxemia-ischemic defeat of the central nervous system
In experiment on white rats (n=20), born after 15 minute prenatal hypoxemia-ischemic, it is studied angio- cyto- and synaptoarchitectonic barks of the big brain within 60 days postnatal the period. It is established, that the prenatal hypoxemia-ischemic in postnatal the period leads to deficiency of the general numerical density neurones (12,1 %), to essential increase in the relative maintenance reactive and destructively changed neurones (to 84%, CI: 75,3-90,6%) and the expressed of synaptoarchitectonic reorganisation, that are not characteristic for normal development in neocortex.