Efficacy of the antiparasitic Fipronil-, Moxidectinand Pyriproxyfen-based drug in the form of spray against entomosis of carnivores
The purpose of the research was to study the efficacy of the drug against entomosis of domestic carnivores. The drug contains such active substances as Fipronil, Moxidectin and Pyriproxyfen, which provide a wide range of antiparasitic effects of the drug. The studies were performed on dogs and cats spontaneously infected with fleas Сtenocephalides felis, Сtenocephalides canis, lice Linognathus setosus and chewing lice Trichodectes canis and Felicola subrostratus in the Moscow and the Moscow Region veterinary clinics from April to December 2021. The diagnosis and efficacy of the drug were confirmed by clinical studies (skin and coat examination for ectoparasites, and live specimens count). The intensity of infestation in entomosis was determined according to the "square" method in areas of the body of 10x10 cm. The animals were divided into control and experimental groups; the drug was not given to the control animals. The experimental animals were treated with the drug once at a dose of 1.5- 3.0 mL per 1 kg of the animal weight. Clinical examination was performed at 24 hours, and at 5, 10 and 30 days. As a result of the studies, 100% therapeutic efficacy of the drug was established after a single treatment against ctenocephalidosis, linognathosis and trichodectosis of cats and dogs.