PREVENTIVE ROLE OF MANDATORY MEDICAL EXAMINATIONS OF EMPLOYEES IN BIOTECHNOLOGY INDUSTRY
A high prevalence of subjective and objective symptoms of disorders in the main organs and systems was established by means of the prescriptive immunoassay results of the in-depth examination of the employees in biotechnology industry (BI). This prevalence was 2.8-16 times higher than in the comparison group. In 67.6% of the examined workers the polysystem and multisystem symptoms of the functional disorders and injures especially as regards respiratory, locomotive system, as well as skin and eyes were observed. Health disorders had typical and specific allergic immunopathologic property and were registered among individuals with little experience of work and increased as far as professional experience extended. It was established that a long-term exposure of the examined BI workers to heteroantigens of various industrial microorganism strains caused a number of effects. In this regard, a list of harmful factors, which are the basis for conducting medical examinations of BI employees should include microorganisms-producers and microbial preparations, products of microbiological synthesis, that in its turn, will result in changes of requirements to conducting medical examinations of these workers and reasonable contraindications for the work in contact with this production factor. Appropriate proposals for amendments and additions to the Regulations on the procedure of mandatory medical examinations of employees were submitted to the Ministry of Health of the Republic of Belarus.