INTRODUCTION OF A METHOD FOR DETERMINING DRUG SUSCEPTIBILITY OF MYCOBACTERIUM TUBERCULOSIS TO NEW ANTIMYCOBACTERIAL DRUGS
Insufficient effectiveness of multidrug - resistant tuberculosis treatment is still a problem in the world. In recent years, new anti-TB drugs have appeared. It is necessary to introduce laboratory tests for their full use. This article presents the results of introducing drug susceptibility tests to Bdq, Lzd, Cfz in the region. All samples of pathological material from MRTB patients were examined in the bacteriological laboratory of Republic Clinical TB Hospital. It was noted that proportion of samples with MBT resistance to Bdq, Lzd, Cfz was 1.9, 4.6 and 2.3 before the start of chemotherapy. Among sputum samples of those who received chemotherapy and did not achieve sputum conversion, this proportion was 9.3, 5.6 and 18.2, respectively. The introduction of a method for determining drug susceptibility to new anti-TB drugs in the region will make it possible to prescribe adequate chemotherapy regimens to MRTB patients, as well as to correct them in a timely manner during treatment course