Study of radioprotective action of ecdysteroids of Serratula coronata the thyroid and adrenal glands of mice
The influence of Serpistene in dose of 5 and 50 mg/kg on chronic low-dose γ-irradiation (22.6 cGy) effects on fuction and morphology of thyroid and adrenal glands mice was estimated. The serpistene modifies effects of γ-irradiation in depends on the administration regime and a dose of the substance. The most expressive radioprotective effect on endocrine organs after Serpistene prophylactic administration was found. The prophylactic dose was 5 mg/kg for adrenal gland and both doses - for thyroid gland.