The transition coefficient of lead from the diet in the liver, kidney and spleen of sheep
On the basis of experimental data obtained at chronic intake of lead from diet in the organism of sheep in concentrations of 5 mg/kg (1 MRL), 25 mg/kg (5 MRL) and 150 mg/kg feed (30 MRL) defined the transition coefficients (TC) from the ration to the liver, kidney and spleen. At concentration of 5 mg/kg of feed (MRL 1) TC of lead from the diet to the liver, kidney and spleen was 0,02; 0,004 and 0,0008, respectively, at 25 mg/kg of feed (5 MRL) - 0,01; 0,002 and 0,0003 and at 150 mg/kg feed (30 MRL) - 0,009; 0,03 and 0,00016. Inverse relationship established between the TC of lead from the diet into organs from the daily concentration of the metal. Comparative analysis of the values TC of lead from diet in the organs revealed significant differences, which are caused, on the one hand, by the physiological characteristics of the liver, kidneys and spleen and their functional activity, and on the other hand, by the distribution of metal in the organism and intensity of its accumulation in the organs.