THE PROSPECTS OF STEM CELL THERAPY FOR THE TREATMENT OF MULTIVESSEL CORONARY ARTERY DISEASE
The paper presents the analysis performed on the basis of the published data on the possibilities of cell therapy in the treatment of ischemic heart disease (IHD) and chronic heart failure (CHF), in particular in multivessel coronary artery disease. The opportunities of the use of different types of cells were studied, it is demonstrated that in the absence of a unified theory of remodeling effect of transplanted stem cells and without clear evidence of the efficacy and safety of cell therapy in the treatment of ischemic heart disease (IHD) and chronic heart failure (CHF), most researchers consider this concept being promising. The experts believe that the application of stem cells could help to solve a number of problems: to prevent post-infarction aneurysm development, to slow down cardiac remodeling process, to reduce foci of necrosis, to improve myocardial condition, function and perfusion – all this ultimately will enhance the effectiveness and safety of the treatment of ischemic heart disease (IHD) and chronic heart failure (CHF).