Effect of the sex steroid hormones on the phenylmethylsulphonilfluoridinhibited carboxypeptidase activity during the stress
Effect of the acute administration of sex steroid hormones - testosterone and progesterone on the phenylmethylsulphonilfluoridinhibited carboxypeptidase that enzyme of neuropeptides exchange activities in the white mongrel mouse regions of the hypotalamopituitaryadrenallgonadal system during the stress were studied. Both steroids partially prevent the increasing enzyme activity that caused stress. The effect of sex steroid hormones on the enzyme activity in female was largest, than male. The effect was not depended on kind of hormones. The effect was largest in pituitary gland and gonads. The role of phenylmethylsulphonilfluoridinhibited carboxypeptidase in regulation of level peptide hormones that controlling the level of sex steroids are discussed.