The efficacy of a new substance of fenbendazole obtained by mechanochemical technology and targeted Drug Delivery System against Nematodosis of sheep
The efficacy studies of a new pharmaceutical substance of fenbendazole produced by nanotechnology with Drug Delivery System were carried out on 45 sheep naturally infected with gastrointestinal nematodes. The new pharmaceutical form of fenbendazole showed 95,67 % efficacy against Nematodirus spp. at the dose of 1,0 mg/kg bw of active substance and 100 % efficacy against other species of gastrointestinal nematodes. Basic drug - fenbendazole (substance) showed 96,39 % and 100 % efficacy respectively at the dose of 10 mg/kg bw