Imbalance of the "ligandreceptor" tumor necrosis factor αsystem and TNFRI expression in thyroid tissue in patients with Graves'' disease
The aim of the study was to examine the system of tumor necrosis factor α(TNFα), depending on the functional and morphological outcome of Graves' disease (GD). It has been shown that activation of TNFαis associated with a “soft” and “benign” clinical course of GD and appearance of morphological markers of autoimmune thyroiditis (Hurthlecells transformation of thyroid epithelium).