Recognition and sensing of guanidine moiety containing biomolecules in aqueous environment
A dicarboxylate based fluorescence receptor has been synthesized for the recognition of guanidinium ion as well as guanidine containing biomolecules in aqueous medium to address the issue of biomolecular interaction. The acyclic receptor has binding ability in 1:2 mode with guests due to its flexibility of the binding motifs. Binding behavior of the host-guest was studied using UV and fluorescence titration methods. In both cases host binds strongly with guanidinium ion over other guanidine containing molecules.