GOUT: EPIDEMIOLOGY, PATHOGENESIS, RISK FACTORS
The results obtained in current studies of gout spread are presented. The ways of purine nucleotides synthesis and urate homeostasis as well as the mechanisms of hyperuricemia development are described. Effect caused by nutrition peculiarities, starvation, obesity, alcohol consumption, arterial hypertension, syndrome of resistance to insulin, some medicinal drugs on the uric acid level is shown