THE EFFECTIVENESS OF HYDROFLUORIC ACID SOLUTION FOR DEEP ETCHING OF TITANIUM IMPLANTS IN HISTOLOGICAL STUDY OF SOFT TISSUES
Background. The purpose of the study is to evaluate the possibility and effectiveness of hydrofluoric acid solution for deep etching of titanium implants in histological study of soft tissues. Material and methods. Two series of experiments were conducted: 1. The occluder was placed into the sexually mature pig’s artificial defect of interatrial septum. Further, the pig was kept for 3 months. At the end of this period, the fragment of the interatrial septum with the occluder was extracted and placed in 10 % formalin. 2. The stent was placed into the sexually mature pig’s aorta. Further, the pig was kept for 6 months. At the end of this period, the fragment of aorta was extracted and fixed in 10 % formalin. Then both fragments were drowned in hydrofluoric acid solution. The received tissue fragments were subjected to standard histological treatment. Results. According to the results of macro- and microscopic research, it was revealed that the structures surrounding the fragment of titanium implants after deep etching did not violate the integrity of soft tissues, the microvasculature vessels, as well as numerous cellular elements, were visible in the field of vision. Conclusion. The results suggest that etching of titanium with a solution of hydrofluoric acid, despite a relatively aggressive effect, does not lead to the destruction of surrounding tissues.