REATMENT OF ORAL LICHEN PLANUS
Objective. To develop a method for treating and preventing various forms of oral lichen planus and evaluate its effectiveness. Materials and methods. 82 patients have been examined clinically for 2012-2016 years including 69 (84.1%) women and 13 (15.9%) men, mean age 56.4±1.5 years, duration of the disease 26.4±5.9 months. The patients are divided into 2 groups.The first group (n=25) consisted of patients with the disease «uncomplicated» (typical and hyperkeratotic) forms.The second group (n=57)included subjects with «complicated» (exudative-hyperemic, bullous, erosive-ulcerative and atypical) forms. All the patients had been divided into 4 groups depending on the treatment method used. The 1st (n=13) and the 3rd (n=33) groups served the main study groups in which the treatment of oral lichen planus was performed in accordance with the method developed by us,the 2nd (n=12) and the 4th (n=24) groups were the comparison groups the treatment was performed according to the protocols of the Ministry of Health of the Republic of Belarus. Results. It was established that after the treatment and prophylaxis of the disease «uncomplicated» forms in the 1st group the duration of the remission period increased in comparison with the 2nd group (18.3±7.9 and 15.9 ±2.1 months, respectively). After 18 months, transition to a complicated form was registered in the 1st group. When analyzing the results of treatment of the complicated forms, it was found that 1 month after the treatment beginning, the complicated form of the disease transited to the uncomplicated one in 46.9±8.9% of cases in the 3rd groupcompared with 12.5±6.9% in the 4th group and the remission period duration in that group increased (11.5±1.04 and 7.0±1.32 months, respectively). Conclusion. The method of treatment and prophylaxis developed and taking into account the disease clinical form and severity based on the individual approach in prescribing local and systemic drugs is significantly more effective than the standard method of treating the disease.