THE FUNCTIONAL CONDITION OF THE LIVER IN LAYING HENS UNDER HEPATOSIS
The article presents the results of the evaluation of the functional state of a liver in clinical healthy and ill with hepatosis laying hens of the “Loman Brown” breed at age 166, 300 and 530 days. The criterion for evaluation was the results of biochemical analysis of blood of laying hens. According to the results, in laying hens with hepatosis liver function disorders have been detected, which were accompanied by hyperproteinemia and increased activity of hepatospecific enzymes. An increase in total protein in sick laying hens was observed at the age of 300 days - by 12.2% (PThe decrease in the concentration of cholesterol in the blood serum was established of ill laying hens at age 166 days (22.7%; PIn addition, there was a decrease in the urea content in the blood serum of ill laying hens at all age groups (166 days - by 10.7%, 300 - by 3.8%, 530 - by 16%), indicating a violation of the urinary and detoxification functions of the liver. The level of uric acid was higher in blood serum in all groups of ill laying hens compared to clinical healthy ones, but decreased by 11.6% and 10.7%, respectively, with respect to the laying hens at age 166 days. The increase of activity of alkaline phosphatase in blood serum in ill laying hens at age 166 days by 8.7; 300 - in 4.1 and 530 - in 6.5 times testifies to the defeat of the biliary tract. The intensity of violations of the functional state of the liver depends on many factors, in particular on the age, physiological state of the organism and the development of the pathological process.