Therapeutic efficacy of antibacterial preparation Nosiheptide 1% in clostridiosis of piglets
Mass antibacterial therapy, carried out according to therapeutic and preventive schemes, is considered to be a highly effective and most rational tool for combating infectious diseases in conditions of large industrial pig breeding. For the treatment of diseases of the gastrointestinal tract of pigs and poultry, company NITA-PHARM has developed a drug containing 1% nosiheptide as an active ingredient. The mechanism of action of nosiheptide is to disrupt protein synthesis in cells of sensitive microorganisms, which leads to their death. Nosiheptide is effective against Gram-positive bacteria resistant to other antibiotics, has no cross-resistance with other antibiotics. Bacteria do not develop resistance after use of the drug. We evaluated the therapeutic effectiveness of the antibacterial drug for veterinary use, containing 1% nosiheptide as an active ingredient, in the case of clostridiosis of piglets on germination. The preparation in the specified dose and method of application has no negative effect on the animal body and is well tolerated. Positive effect of Nosiheptide 1% in dose 500 g/ton of fodder for 10 days on absolute and average daily gain of live body weight of piglets was found. It is related to the normalization of bacterial microflora and the improved assimilability of fodder.