CHANGES IN CELLULAR COMPOSITION AND CONCENTRATIONS OF SERUM PROTEINS IN THE BLOOD OF CLINICALLY HEALTHY COWS IN A DRY PERIOD
The study of the influence of dry period on cellular composition of the blood and content of serum proteins of the clinically healthy 5-6 year old cows of the black-mottled species is performed in the Perm experimental- training farm «Lipovaya gora». During the first day of dry period the coefficients of variation in the results of studies in the different samples comprised from 8±1 to 43±6%. Consequently, the parameters in the samples obtained from the cows at the beginning of dry period can not obey the law of normal distribution. Therefore the authenticity and the direction of possible changes were evaluated according to the W. Wilcoxon's test. While the erythrocyte concentrations in the blood of cows in the middle and in the end dry period did not change, the average content of hemoglobin has decreased. The segmentonuclear neutrophils, 0-lymphocytes and monocytes, and also serum albumin and globulins content have incresed. The content of IgG in the blood has decreased, and while the concentration of IgM is considered normal, it has definitely increased and hence it can partially compensate for the decrease in IgG concentration without adverse effects on the fetus. The concentration of IgA in the serum at all times of the dry period is above normal. This indicates an increase in the activity of the humoral mechanisms of specific protection of the cow and the developing fetus from infection by pathogens in the external environment and the creation of conditions for the accumulation of IgA in the mammary glands. The scatter of the measured parameters during 60 days has decreased by approximately two times, and the average value of the coefficients of variation reached the limit between weak and average scattering. Consequently, at the end of the dry period, the scattering of indicators in the samples became more consistent with the normal distribution.