POST-VACCINATION IMMUNITY IN DOGS VACCINATED AND TREATED AGAINST THE PARVOVIRUS ENTERITIS
In this article we present the results of studies aimed at establishing the level of post-vaccination antibodies to parvovirus enteritis. The work was performed on dogs 1.5…2 months old. The animals were divided into two groups. In the first group, dogs were vaccinated and treated against endoparasites according to all instructions. Dogs of the second group were also vaccinated, but were not exposed to anthelmintic treatments. Further, the state of the experimental animals was monitored with the methods of clinical examination, coproscopic, hematological, biochemical and serological researches. Dogs not treated against endoparasites showed symptoms of parvovirus enteritis by the 6th day of the experiment. Coproscopic research indicated an invasion of Toxocara canis by nematodes. Hematological research showed a decrease in the level of hemoglobin, hematocrit and platelets. The results of biochemical research showed a decrease in the level of albumin and total protein. During a serological research (ELISA), the development of extremely low antibody titers was noted. The dogs of the first group did not show any signs of deterioration in health. Indicators of hematology and biochemistry were within the physiological norm. The ELISA results indicated the development of antibodies to parvovirus enteritis. This research confirms the need for anthelmintic treatments before vaccinations.