The development of inactivated emulsified vaccine against duck viral hepatitis type I
The primary stage in the fight against duck viral hepatitis type I (DVH-1) in parental flocks of ducks is the use of specific prophylactic agents. The main stages of the technology of inactivated vaccine against DVH-1 are presented. The parameters for the obtaining of virus-containing material, purification, antigen concentration, inactivation of the viral genome, and inclusion of an adjuvant in the vaccine composition were optimized. It was shown that the vaccine has high immunobiological activity and can be used for specific prophylaxis of this disease.