SUBSTANTIATION OF THE PREVENTIVE ACTION MECHANISMS OF APPLE PECTIN’S COMPOSITION OF THE INTESTINAL RATS AT LEAD INTOXICATION
Experiments on rats shows, that inside gastric introduction of an apple pectin’s composition in a doze of 400,0 mg/kg reduces parameters of sharp toxicity an acetate of lead in 1,44 times. At long inside intraperitoneal influence an acetate of lead in a doze 1/50 DL 50 in a doze of 400,0 mg/kg apple pectin’s raises an activity of motor-evacuation functions of gastrointestinal tract, warning a delay of lead in a gleam of intestines. They are changing functional characteristics of the intestinal slime to surfaces of a mucous membrane of a thin gut structurally, providing its protection against toxic influence of metal; warning a development of an atrophy of a mucous membrane of thin intestines and normalizing a condition microbiocinosis a thick gut which infringement takes place at a lead intoxication. The results which were received in experiment open a new data about pectin’s mechanisms substances action at a level of a gastro enteric path allow proving their application for collective and individual biopreventive maintenance of lead poisonings.