BLOOD PROTEINS AND THEIR INFORMATIVENESS IN ASSESSING THE ADAPTIVE RESOURCES OF CHICKENS UNDER TECHNOLOGICAL STRESS
In the body of chickens, when exposed to the technological factor (the density of birds in the cage), a stress reaction developed as a result of activation of the hypathalamic-pituitary-adrenal system. The response and state of the neuroendocrine pathway is associated with the magnitude of the technological stress factor. When it is increased by 1.50 times, the maximum changes in the body of chickens are detected 4 hours after the start of the experiment. At the same time, the level of corticosterone and cortisol in the blood of birds increases by 3.42 and 2.99 times, increasing the rate of catabolic reactions in protein metabolism. Therefore, the amount of total protein in the bloodstream of chickens increases by 34.32 %, albumins by 26.74 %, urea and uric acid by 2.07 and 2.29 times, and the activity of AsAT and AlAT increases by 2.15 and 4.53 times (p<0.05). The catabolic processes involve mainly blood albumins, whose nitrogen is used for the synthesis of uric acid. This is evidenced by a decrease in the value of Alb/uric acid by 42.74 % (p<0.05). With an increase in the density of birds in the cage by 2 times, the reaction of the GGNS more pronounced and long-lasting. Although the maximum changes are registered 2 hours after the initiation of stress, they persist throughout the study period. At the same time, the level of corticosterone and cortisol in the blood of chickens increases by 4.17 and 3.67 times, the concentration of total protein by 39.44 %, both due to albumins (by 41.78 %) and globulins (by 37.82 %); the increase in the amount of urea and uric acid is 2.18 and 2.45 times. Both albumins and blood globulins are subjected to oxidative decomposition, which determines the decrease in the ratio TP/Urea, Alb/urea at, TP/uric acid and Alb/uric acid at 35.72-43.18 %. At the same time, the activity of AlAT increases by 7.56 times and AsAT by 2.21 times, determining the predominant use of carbon residues of free amino acids in the processes of gluconeogenesis (AlAT/AsAT increased by 3.75 times).