Defensins - multifunctional cations peptides of human
The production of natural cationic antimicrobial peptides is an important mechanism of human innate immunity. Human Defensins belong to the family of cationic trisulfide-containing microbicidal peptides. Beside their direct antimicrobial function, defensins have multiple roles as mediators of inflammation, exert chemotactic, immunomodulating and cytotoxic activity and other. Further, defensins qualify as innovative drugs that might be used as antibacterial drugs, as modulators of inflammation drugs and in cancer therapy.