IMMUNE STATUS OF THE ACTIVE AND PASSIVESMOKING TEENAGERS WITH PATHOLOGY OF RESPIRATORY ORGANS
Studied the immune status in active and passive smoking teenagers with pneumonia, chronic bronchitis and atopical bronchial asthma (ABA). In healthy patients active and passive smoking caused an increase in the number of peripheral blood B-lymphocytes and CD25+-cells. In acute pathologies passive smoking, compared with the active, causes a significant change in the levels of CD3 + -, CD4+ and CD8+ -lymphocytes, cells with markers of activation and IgM IgG, TNF-α. When ABA active and passive smoking, compared with nonsmokers causes a significant increase in B-lymphocytes, CD25 + -, HLA-DR+-cells, TNF-α, IL-8 and, conversely, decreased IFN-γ. The revealed changes in smokers adolescents indicate the expressed negative influence of active and passive smoking on the immune status, as healthy adolescents and persons with different bronchopulmonary pathology.