THE EFFECT OF ASSOCIATED USING PROBIOTIC IN COWS AT LATE PREGNANCY AND NEWBORN CALVES ON FORMATION OF BIOTOPE MICROBIOCOENOSIS AND THEIR CLINICAL PARAMETERS
The research results showed that the associated using of “Subtilis-G” probiotic for upper air passages and “Prolam” probiotic drug with intravaginal introduction of “Simbiter-2” or “Giprolam” to cows at late stages of gestation promoted the indigenous microflora in maternal passages at physiological level and improved gut microbiocenosis formation in newborn calves. As a result of both the biotypes physiological microflora colonization and microecological preparation of cows' maternal passages, the newborns' intestine microbiocenosis had a higher level of Bifidobacteria, lactobacilli, lactose-positive Escherichia, saprophytic staphylococci and relatively lower level of potentially pathogenic microorganisms (enterococci, bacteria of citrobacter, enterobacter, proteus species, lactose-negative Escherichia) in comparison with biocenosis in intact animals. Microbiocenosis of upper air passages was characterized by high content of saprophytic (Staph. hyicus, Staph. saprophyticus и Staph. epidermidis) microorganisms and by low content of conditionally pathogenic (staphylococcus aureus, hemolytic staphylococcus, streptococci of C and D groups, Escherichia, enterobacteria, etc.) microorganisms in comparison with biocenosis in intact animals. Improving the intestine microbiocenosis formation and upper respiratory tract in newborn calves significantly reduces sickness rate of gastrointestinal and respiratory diseases.