The experimental laboratory model of relief brucella infection
Guinea pigs experimentally infected with strain 16M B. melitensis. Injection of antibiotic drug Nitoks-200 in a dose of 20 mg/kg body weight followed 8 days later by conjunctival immunization by vaccine strain 19 B. abortus at a dose lower 10 times than recommended for subcutaneous administration provides during 1 month complete elimination virulent brucella strain from organism of laboratory animals. It was impossible to achieve such result with only drug Nitoks-200 or above mentioned vaccine.