BLOOD SERUM BIOCHEMICAL INDICES IN CALVES WITH CONJUNCTIVO<i>-</i>KERATITIS WHEN TREATED WITH LIGFOLUM DRUG
Conjunctivo-keratitis is an eye disease characterized mainly by inflammation of the conjunctiva and cornea. The disease is manifested in various forms and severity of inflammation. Conjunctivo-keratitis causes serious economic damage due to its high frequency of manifestation and widespread prevalence both in our country and abroad. In calves, the disease is accompanied by depression, loss of appetite, and decreased body weight gain. It is of interest to monitor the changes in some biochemical indices of blood serum (total protein, albumin, ALT, AST, and LDH) during conjunctivo - keratitis cases in young cattle and to monitor the dynamics of these indices when treated using the domestic drug Ligfolum in combination with various drugs. Blood serum biochemical indices reflect objectively the metabolic status in animals and help evaluate the effectiveness of a particular treatment approach. Blood serum biochemical indices characterize the functional activity of individual organs and systems and the homeostasis of the body as a whole. The study was conducted in 4 groups of animals with clinical manifestations of conjunctivo - keratitis . The groups consisted of 8 calves housed under the same conditions. A separate treatment regimen was chosen for each group. It was found that the indices of albumin and total protein fluctuated slightly. The most significant deviations of the indices in comparison with the first day of treatment were identified in groups 1 and 4. The indices of LDH activity throughout the treatment remained within the physiological range. No significant differences in the biochemical indices of blood serum depending on the treatment regimen were found.