ESTIMATION OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH IHD AFTER STENT IMPLANTATION WITH OR WITHOUT THE SUBSEQUENT RETHROMBOSIS
In this study, we defined a role of endothelial dysfunction at stent rethrombosis, by comparison of an expression of soluble molecules of intercellular adhesion (ICAM, VCAM, P, E - selektine) in patients with different forms of IHD after stent implantation with or without the stent rethrombosis. This study investigated levels of circulating intercellular adhesion molecules were in 70 patients with different forms of IHD with or without the stent rethrombosis after stent implantation. In the first group 35 patients with stent thrombosis have been carried. In the second group 38 patients with heart attack of a myocardium without complication in a kind of stent thrombosis have been carried (the period of supervision have made within 1 year). Comparison group has made 35 conditionally healthy people. Patients with IHD stent thrombosis have a higher level of molecules of intercellular adhesion ICAM, VCAM, P-selektine that reflects presence of inflammatory process and endothelial dysfunctions. The further studying of markers endothelial dysfunction does possible working out of the prognostic concept for diagnostics of complications after endovascular treatments IHD.