HEMATOLOGICAL INDICATORS AND NATURAL RESISTANCE OF SHEEP AFTER CORRECTION WITH " SEDIMIN" UNDER TECHNOGENIC POLLUTION CONDITIONS
The waste storage facility of the «Tuvakobalt» mining plant continues to be one of the environmentally hazardous facilities in the Republic of Tyva. Various disorders in the functioning of the hematopoietic and immune systems, cytogenetic disorders, manifested by an increase in the frequencies of fragments and chromosome breaks are recorded in farm animals kept in contaminated areas. Preparations containing selenium are widely used to reduce the level of free radicals and remove toxic compounds from the sheep’s body. In this work we studied the effect of the antioxidant enzyme «Sedimin» on the hematological parameters and natural resistance of Tuvan short-fat-tailed sheep bred in the area of «Tuvacobalt» mining plant contaminated with toxic waste. The assessment of hematological blood parameters indicates that after the administration of «Sedimin», the hemoglobin level in the blood of sheep increased by 16,5 % (P < 0,05), the number of erythrocytes and leukocytes increased by 10,11 and 11,40 %, (P < 0,05) compared with sheep that did not receive the «Sedimin», which indicates an intense saturation of tissues with oxygen and activation of redox reactions. The positive effect of the «Sedimin» on the state of natural resistance of sheep was established, which is confirmed by an increase in the phagocytic activity of leukocytes by 19,32 %, the phagocytosis index - by 31,33 %, an increase in the bactericidal activity of blood serum by 17,11 % and and lysozyme activity of blood serum - by 14,8 % (P <0,05 - 0,01).