FEATURES OF OSTEOGENESIS IN THE IMPLANTATION OF TITANIUM IMPLANTS SUBJECT TO MICRO-ARC OXIDATION IN ALKALINE ELECTROLYTES CONTAINING CA AND P USING THE "COLLAPAN-GEL" AND WITHOUT
Background : comparative study of the features of reparative processes in the bone during installation of titanium implants with sandblasted exposed microarc subsequent oxidation in alkaline electrolytes containing Ca and P, with the osteoinductive preparation and without. Materials and methods. Histologically are examined 24adult rabbits tissue samples from the body area of titanium implant with osteoinductive preparation and without 7, 14, 28, 56 and 112 days after operation. Results. It is revealed that the implantation of titanium implants subjected to micro-arc oxidation in alkaline electrolytes containing Ca and P and without the use of osteoinductive drug leads to poorly pronounced inflammatory response and the processes of bone formation takes a longer period of time. The usage of identical implants with osteoinductive preparation "CollapAn-gel" led to a less pronounced inflammatory response and a more active process of bone formation. Conclusion. The use of titanium implants subject to sandblasted microarc oxidation in alkaline electrolytes containing Ca and P can be effectively combined with osteoinductive agents to get the best clinical outcomes and achieve shorter bone restoration terms.