Selective Synthesis of Functionally Substituted 1,2,3-Triazoles
During work various options of an enolate-azide cycloaddition with selective formation of 1-aryl (hetaryl)-4.5disubstituted-1,2,3-triazoles are considered; optimal conditions for carrying out the bromination reaction of 1(5-methyl-1-phenyl-1,2,3-triazol-4-yl)-ethanone with output to the desired α-monobromosubstituted ketone are determined.