THE ROLE OF POLYMORPHIC VARIANTS OF CYTOKINE FAMILY GENES IN DEVELOPING BRONCHIAL ASTHMA IN THE REPUBLIC OF BASHKORTOSTAN
The aim of the work was to determine the role of gene polymorphism of the cytokine at the risk of developing bronchial asthma. The analysis of polymorphism of cytokine genes was carried out by polymerase chain reaction of DNA synthesis in real time. Statistical analysis was carried out using the χ2 criterion, taking into account the Yates amendments. The study has shown that in patients with bronchial asthma the T allele and the TT genotype of the polymorph variant rs3939286 of the IL-33 gene are more common than in the control group. The results suggest that cytokine genes are involved in the development of bronchial asthma.