LIPIDS END PHOSPHOLIPIDS OF LAYING HUMANS TUBULAR BONES IN DIFFERENT GEOCHEMICAL CONDITIONS
Methods of histochemistry and transmission electron microscopy were studied content and localization of lipids and phospholipids in laying thighs from 6 to 12 weeks of prenatal development in different geochemical conditions of the Lower Volga (Astrakhan) and the North Caucasus (Makhachkala). Observed formation of osmophilic lipid containing bodies – vesicles matrix, from cellular wall of chondrocytes, especially in the zone of hypertrophy metaepiphysis cartilage, and output data of bodies in the intercellular space. Determined more intense, a statistically significant increase in the number of vesicles matrix in the growth zone of laying thighs in Makhachkala compared to Astrakhan studied at all stages of prenatal ontogenesis. This fact combined with a large number of vesicles matrix in geochemical region with higher mineralization of the environment. If ossification and mineralization laying thighs of man in them there is a decrease in the content of neutral lipids. On the contrary, the content of phospholipids increases due to their representatives – activators of mineralization. These processes faster go in geochemical area with high mineralization of the environment.