Comparative efficiency of hepatoprotective treatment plans of dogs in associative course of leptospirosis and babesiosis
Clinical signs, morphological and biochemical parameters of the blood of dogs were studied, in which by polymerase chain reaction the associative course of leptospirosis and babesiosis was diagnosed. Clinical signs of the disease: oppression, anorexia, temperature rise to 39.5-40.5 °C, pronounced biliousness of visible mucous membranes, hemoglobinuria, diarrhea. Morphological blood parameters were characterized by erythrocytopenia against the background of monocytosis, leukopenia with a regenerative shift of the nucleus to the left, a decrease in hemoglobin. A biochemical blood test showed a sharp increase the level of alanine aminotransferase, alkaline phosphatase and bilirubin. The comparative efficacy of various hepatoprotective treatment plans in dogs was carried out. The most effective medications from a therapeutic point of view was: Sinuloks, Metrogyl, Pyro-Stop, Liventsiale, Hepa-Merz, 40% glucose solution and 5% ascorbic acid solution.