IMPROVING OF BRONCHIAL ASTHMA BASICAL PHARMACOTHERAPY AT REHABILITATION STAGE IN SANATORIUM
This study involved 62 patients, aged 12,6±1,7 years, 38 males (12,7±1,7 years) и 24 females (12,6±1,8 years), diagnosed with persistent moderate bronchial asthma (BA). The study was conducted to determine the optimal mode of combination of basic pharmacotherapy in this cohort at rehabilitation stage in sanatorium stage and for the 6-months’ follow-up period. Patients received either free combination (31 pers. 11,8 ± 1,6 years, 20 boys and 11 girls) inhalation of inhaled corticosteroids (ICC) and β2-agonist long-acting (LABA) or fixed combination (31 pers. 11, 8 ± 1,6 years, 19 boys and 12 girls) of ICC and LABA. Each patient during the course of sanatorium treatment and 6 months of follow-up has four scheduled visit. Asthma-test (AST), spirometry, PAQLQ(S) questionnaire, - were used in monitoring clinical signs of asthma. The data was analysis with SPSS 19.0. The best values of respiratory function (spirometry) was in the free combination group till 3 months of follow-up period. Also in this group the rescue medication using and doctor’ unscheduled visits were lower, and the results of AST and PAQLQ(S) - were better, - till 6 months of follow-up (p <0,05). Basing on these data, the algorithm of the optimal approach to the management and monitoring of asthma at rehabilitation stage in sanatorium was developed.