Juxtamedullary blood flow pathway
Golubev V.Z. created a scientific basis for the study of microangioarchitecture of the kidneys. The principles outlined in his thesis mediated appearance of studies investigating juxtamedullary blood flow and renal blood circulation in normal and pathological conditions.In acute cardiovascular diseases, the value of the juxtamedullary path of the blood flow increases and juxtamedullary shunting is observed. In chronic cardiovascular diseases, the juxtamedullary shunting initially increases and in the later stages of the disease, the sclerosis of the renal medulla causes a reduction and block of the juxtamedullary blood flow both the juxtamellular and the cortical blood flow deteriorating, which leads to a failure of the circulation to the heart flow. Through research Golubeva V.Z. modern information about the pathways of renal blood circulation prepared, allow to explain the mechanism of the development of various pathological conditions: acute blood loss, hydronephrosis, renovascular hypertension, glomerulonephritis, pyelonephritis, urolithiasis and another nephrological and urological diseases, cardiogenic shock, cardiorenal syndrome in acute ischemic heart disease, hypertension, sudden coronary death, and others.