BIOLOGICAL EFFECT OF THE INFLUENCE POTASSIUM IODIDE ON THE ACTIVITY OF ENZYMES OF ANIMALS
The article presents the results of the evaluation of the influence of crystalline and colloidal potassium iodide on the activity of enzymes in blood and liver of animals. The experiment was performed on adult male rats Wistar rats weighing 210-230 g, which formed 4 groups (n=7): I - control animals were kept on standard food and water diet; II, III and IV - experimental rats for 30 days in a feed to balali potassium iodide kalia (in II group in the crystalline state in a daily dose of 10 mg/kg; III and IV groups in the colloid at the rate of 10 and 5 mg/kg, respectively). It is established that 30-day enrichment of feeding crystalline and colloidal potassium iodide promotes the catalytic activity of alkaline phosphatase and γ-GTP in the blood and the supernatant of the homogenate of the liver due to the metabolic effects of enzymes. Maximum level of enzyme activity increases after oral intake of animals colloidal potassium iodide in a daily dose of 10 mg per 1 kg of live weight. Catalytic activity of alkaline phosphatase and γ-GTP, compared with the control, in the blood increased by 27,72 (p<0.001) and 74,79% (p<0.001) in the supernatant of the homogenate of the liver - of 43,89 (p<0,001) and 44,27% (p<0,001), respectively, indicating that activation of the exchange monophosphates and amino acids. The concentration of arginase in the liver, on the contrary, reduced by 22,29% (p<0,01), as a result of activation of protein synthesis in organ.