The Influence of Trace Element Imbalance in Women on the Occurrence of Peritoneal Endometriosis
The objective of the study was to determine the effect of the level of some of the essential trace elements and ultramicroelements in the female body in peritoneal endometriosis. Materials and Methods. We examined 40 patients, residents of Donetsk region, with confirmed peritoneal endometriosis and 30 apparently healthy women without gynecological pathology. We investigated the blood serum using colorimetric, spectrophotometric, potentiometric methods, ion-selective analysis to determine the structural content (magnesium, sodium, phosphorus, calcium ionized), essential trace elements (iron, zinc, selenium, lithium, copper) and ultramicroelements (mercury, lead). Results. There was detected a significant increase in blood serum levels of iron by 1.43 times (21.29 ± 1.05 vs. 14.87 ± 0.21 mcmol/l in control), phosphorus — by 1.22 (1.35 ± 0.06 vs. 1.10 ± 0.01 mmol/l), copper — by 1.05 (21.43 ± 0.57 vs. 20.42 ± 0.30 mcmol/l), against significant reduction of magnesium by 0.86 times (0.80 ± 0.01 vs. 0.94 ± ± 0.00 mcg/dl), lithium — by 0.79 (0.87 ± 0.00 vs. 1.10 ± 0.00 mmol/l), zinc — by 0.80 (92.08 ± 2.10 vs. 115.44 ± 3.21 mcg/dl), selenium — by 0.88 (89.00 ± 1.69 vs. 101.58 ± 0.82 mcg/l), mercury — by 0.74 (0.38 ± 0.01 vs. 0.52 ± 0.01 mcg/l), lead — by 0.83 (22.76 ± 0.67 vs. 27.33 ±± 0.86 mcg/l). This study showed no significant differences in the content in blood serum of such trace elements as sodium, ionized calcium. Conclusions. Trace element imbalances arising in the female body in peritoneal endometriosis requires careful correction, which in the future may help to reduce the frequency of relapses.