Influence of Dipyridamole and Its Derivatives on Chromatophore Membranes Energization State of Bacterium Rhodobacter sрhaeroides
Mechanisms of specific influence of dipyridamole therapy remain subject to further research. In the present work the effects of dipyridamole and some its derivatives on energization state of photosynthetic membranes of purple bacteria chromatophores have been studied. It is shown that at illumination of chromatophores in the presence of dipyridamole the occurrence of its radical form due to the presence of electron-proton donation properties is observed. It is these properties that are key to trigger energization of functionally active photosynthetic membrane when it is illuminated in the presence of dipyridamole and its derivatives. It is obvious that these properties of dipyridamole should be taken into account while studying the effects of this agent as medical preparation of specific action.