Perfusion computed tomography in gastric cancer diagnostics and treatment efficacy evaluation (literature review)
Introduction. Gastric cancer remains one of the most common causes of cancer deaths worldwide. Introduction of 320-slice multispiral computer tomographs, high-field MR scanners (3T) has provided high-quality visualizing images of organs and systems. New imaging methods provide not only imaging of the organ structure, but also allow assessing the metabolic and functional state of various organs and types of lesions. CT perfusion is one of these methods. It is since recently used to diagnose gastric cancer. Material and methods. The conducted literature review has covered the PubMed database for the period of 2008 2018. Search was performed by keywords “Perfusion CT, gastric cancer'. Of the 25 sources, only 14 scientific publications met the established selection criteria. Literature review. A review of the literature about perfusion CT of gastric cancer is provided. Study of intratumoral hemodynamics, or so-called tumour perfusion, is necessary to understand the status of cancer. The parameter for non-invasive preoperative evaluation of tumour perfusion has not been developed yet. Conclusion. CT perfusion parameters can serve as indicators of the degree of malignancy and prognostic evaluation of gastric cancer. They allow evaluating the efficacy of neoadjuvant chemotherapy in patients with advanced gastric cancer. Perfusion CT of gastric cancer requires further study.