RESEARCH OF CHANGE OF KINETICS OF GROWTH OF RECURRENT AND METASTATIC TUMOURS UNDER THE INFLUENCE OF CHEMOTHERAPEUTIC TREATMENT
Article is written in sections of theoretical and practical oncology and devoted to recurrent and metastatic tumors. As the main predictive criterion for recurrent and metastatic tumors authors chose the speed of their growth. Efficiency of chemotherapeutic treatment is estimated in respect of its influence kinetics of growth of tumors. With application of morphometric techniques the structure of five different types of recurrent and metastatic tumors is investigated. Authors developed original model of tumoral growth. On the basis of model the computer program allowing to count kinetic parameters of growth of a tumor is created. The chemotherapy effectiveness ratio received by comparison of growth rates of tumors of the patients who were receiving and not receiving chemotherapy is offered. It is analyzed changes of effectiveness ratio of chemotherapy at various combinations of kinetic parameters.