DEVELOPMENT OF METHODS FOR APPLYING SUPRAMOLECULAR STRUCTURES ON THE SURFACE OF CAPILLARY COLUMNS FOLLOWED BY THE SEPARATION OF HALOALKANES AND ALCOHOLS
A new method of forming supramolecular structures on the inner surface of the capillary column on the stationary phase of cyanuric acid was studied. A technological device was developed for washing and blowing a capillary column. The adapter consists of four links of cut pieces of heat shrinkable tubes. The cyanuric acid was modified from an aqueous solution by evaporation of the solvent at 60 °C. Using a Tescan Mira 3 LMH microscope, the samples of a capillary column were studied for the presence of suprastructures by the method of the electron microscopy. The separation of two adjacent peaks was characterized by the resolution Rs. The analysis proved the presence of a polycrystalline state, which occurred as a result of the interaction of the column with the sorbent. Enantioselectivity of haloalkanes (2-chlorobutane, 2-bromopentane, 1,2-dichloropropane) and alcohols (2-pentanol) on the resultant capillary column modified by solution of cyanuric acid was studied. The coefficients of selectivity and the separation of enantiomers were calculated. The best separation for 2-chlorobutane was observed at a thermostat temperature T = 85 °С with a selectivity factor α = 1.31, with a resolution of Rs = 0.455. The highest coefficient of selectivity for 1,2-dichloropropane was obtained at 110 °C with a selectivity factor α = 1.37, with a resolution of Rs = 0.544. Enantioselectivity for 2-bromopentane and 2-pentanol was observed at temperatures T = 105 °C (α = 1.52) and T = 110 °C (α = 1.42), respectively.