Clinical peculiarities of perinatal and prepuberty periods of the adolescent girls with abnormal development of the reproductive function
Aim of this research was the evaluation of the perinatal period and prepuberty in the adolescents with different abnormalities of the development of reproductive function. Material and methods. Complex prospective clinical and laboratory examination of 180 adolescent girls (12-18 years old) with different abnormalities of the development of reproductive function was performed and the control group consisted of 56 adolescent girls with normal puberty. Study results: somatic and obstetric pathology was revealed in the mothers of the girls from the main group. The following diseases were typical for the girls with different abnormalities of the development of reproductive function: often virus infections (58,75% in the main group and 31,25%, p<0,01), gastrointestinal pathology: chronic gastroduodenitis, chronic enterocolitis and dyskinesia of bile passage system (55% in the main group and 12,5% in the control group, p< 0,01). Frequency of allergic diatesis in the early childhood was significantly higher than in healthy girls ( 21,25% in the main group and 6,25% in the control one, p< 0,01). Conclusion: the research testified to the existence of the perinatal and somatic pathology in adolescent girls before the appearance of the abnormalities of the development of reproductive function.