Results of the Blind Placebo-Controlled Trial of the Novel Anti-Stress Drug Anoten Efficacy against Neurotic Disorders in Dogs
The blind placebo controlled trial was conducted in 20 dogs with signs of neurotic disorders to confirm the efficacy and safety of the anti-stress and antianxiety drug Anoten. Clinical and emotional-psychological state of animals was recorded every day during the 14 days. The obtained data showed that emotional and mental state was improved in dogs receiving Anoten compared with dogs receiving placebo according to RASS (Richmond Agitation Sedation Scale) and integral scales. Differences between groups were statistically significant. Clinical scores of animals were similar in Anoten and placebo groups, which proves the drug’s tolerance and safety.