Usage of modern techniques of neuroimaging in diagnostics of addictive disorders
The results of the diagnostic potential of addictive disorders among troops with clinical and laboratory and instrumental methods are presented. Using functional magnetic resonance tomography it was found that in patients with opioid addiction, compared with healthy individuals, there are statistically significant functional changes in stem structures, prefrontal cortical areas and structures of the hippocampus. In this case, evidence of organic lesions of these brain regions in structural magnetic resonance imaging was revealed. In all the examinees there were found high levels of state anxiety, suicide risk, depression and anhedonia syndrome. Identified neurological symptoms indicate the diffuse nature of the nervous system in patients suffering from drug addiction. According to the research of biochemical indices of oxidative stress, cytochrome P-450 specifies the duration of remission for opioid addiction. This research reflects the stage of experimental point of specific neurofunctional and biochemical changes of addiction pathology, which can detect inclined to addictions, defines a «group of risk».