Molecular Evolution Structure of Gene Controlling Synthesis of Urat Oxidase
Uricase activity is absent in humans and other certain primates. Analysis of structural organization of uox gene showed, that uox gene consists of a short conservative region unchanging in all investigated vertebrates. The genetic distances in primates group do not exceed the distances between close species of M. мusculus and Rattus norvegicus. However, uox gene is not constant and occurring the evolutionary change of the uox gene.