STUDY REGENERATION OF CARTILAGE AND BONE TISSUE IN MODELING SLIT-SHAPED OSTEOCHONDRAL DEFECTS PATELLAR FEMORAL CONDYLE SURFACE IN EXPERIMENT
The details of posttraumatic process and regeneration studied using an experimental model of canine split-like osteocartilaginous intraarticular defect. The self-healing has been demonstrated to pass through the stage of connective tissue formation followed by subsequent replacement with bone and fibrillary connective tissue. As far as the experiment period increases, the fibrillary connective tissue differentiates into the cartilaginous one (of fibrillary and hyaline-like type). Full restoration of subchondral bone doesn’t occur in the defect zone by four months of the experiment, even in case of maximal juxtaposition of fragments, and newly-formed regenerative tissue protrudes over the articular surface. At the same time, a high risk of osteoarthrosis takes place.