MICROSCOPIC CHANGES IN THE LIVER, KIDNEYS AND PANCREAS OF DOGS IN CASE OF EXPERIMENTAL ENTERAL SARCOCYSTOSIS
Researchs on the distribution of sarcocystosis among dogs in Ukraine have not been carried out. In an accessible world literature postmortem changes in case of sarcocystosis of dogs are described insufficiently. The aim of our study was to examine microscopic changes in the liver, kidneys and pancreas of dogs in case of experimental enteral sarcocystosis. The liver, kidney and pancreas of three pups, experimentally infected with Sarcocystis, were used in our investigation. For histological studies, selected pieces of those organs were fixed in 10% neutral aqueous solution of formalin and, after dehydration in ethanols of increasing concentrations and chloroform, were embedded in paraffin. Slices with thickness of 7 - 10 microns were obtained by using sledge microtome. To detect microscopic structure of organs sections were stained with hematoxylin and eosin. In the liver of dogs, in case of experimental enteral sarcocystosis, granular dystrophy and destruction of the hepatocytes and interlobular proliferation of fibrous connective tissue were recorded. In kidneys extracapillary serous glomerulonephritis and granular dystrophy of epithelium of convoluted and straight tubules were detected. In the pancreas microscopically the swelling, disruption and destruction of individual acinus of the gland were found out.