Experimental models a heart failure: condition of a question and results own research
Work is devoted to the comparative analysis of productivity and reproducibility of experimental models of a heart failure at rats. It is established that phenylephine hydrochloride introduction (0,1 ml of 1% of solution intramusculary) daily within 21 days with an exercise stress 25-30 min. allows to receive a chronic heart failure most close reflecting the main stages of development of the pathological process meeting in clinical practice at patients CHF. This model of a heart failure it is possible to survey as easily feasible, the most effective, bringing to development of the expressed and permanent changes in heart, characteristic for a chronic heart failure at animals.