Definition of Inhalation Danger of Volatile Components of the Drug in Dust Form from the Synthetic Pyrethroids Group under Repeated Influence
In veterinary medicine and medicine for the control of ectoparasites of animals and humans drugs and products from various groups of chemical compounds including synthetic pyrethroids are used currently, but the development of resistance to these substances is registered in many species of parasitic arthropods. One of the most effective ways to overcome of resistance is to replace the currently used drugs with other ones containing 2…3 active substances that have a synergistic effect. However, it is necessary to find out the safety of the studied drugs and their toxic effects on the organism of laboratory animals for their use. During the study of the inhalation danger of the volatile components of insulinicaricide dust in laboratory animals we revealed that the inhalation of vapors of the increased rate of consumption was 10 times did not change the parameters in the experimental rats. According to the limiting criterion for assessing the safety of insecticidal preparations in the zone of acute biocidal effect), the dust belongs to the 4th class of low-hazard substances according to the Classification of the degree of danger disinsection agents.