Pathogenetic pathways of maladjustment of the cardiovascular system in neonates and prospective analysis of follow-up data
Aim. To explore the dysfunctional status of cardiovascular system during postnatal adaptation. To perform a retrospective analysis of the course of pregnancy in mothers of examined newborns and catamnestic analysis. Material and methods. A total of 282 full-term infants born from mothers with various extragenital pathology were included; retrospective analysis and prospective analysis were performed of all mothers; children catamnestic analysis was performed in newborns with cardiovascular system dysfunctions. Results and discussion. Dysfunction of the cardiovascular system (CVS DF) in the early neonatal period was found in 66.3% of the surveyed newborns. As a result of comparison the impairments of mother with her newborn dysfunctional state, a clear pattern has been established. Conclusion. Causal factors negatively affect perinatal outcomes, causing the failure of adaptation process and the development of pathological conditions in the newborn in the early neonatal period.