THE INDICES OF MOR PHO-BIOCHEMICAL BLOOD STATUS OF COWS WITH CHRONIC UTER INE DISEASES OF A FUNCTIONAL NATURE
The development of chronic uterine subinvolution is accompanied by an increase in the level of eosinophils by 14.3 %, compared with clinically healthy animals, middle molecular peptides - by 14.3 % (P <0.01), with a decrease in content of vitamin A by 11.3 %, vitamin E - by 7.4 %, estradiol - by 34.9 % (P <0.01), progesterone - by 33.8 % (P < 0.05), cortisol - by 9.3 %, indicating minor effects of intoxication, the accumulation of toxic products, the intense functioning of the LPO-AOS system and the hypofunctional state of the ovaries.Cystic glandular hyperplasia of the endometrium is characterized by a sharp increase in the content of eosinophils - by 2.8 times higher (P < 0.001), circulating immune complexes - by 1.92 times (P < 0.001), the amount of stable nitric oxide metabolites - by 1.81 times (P < 0.001), estradiol - by 7.8 times (P < 0.001), with a decrease in progesterone by 2.08 times (P < 0.05), cortisol - by 16.6 %, indicating the development of allergic reactions, hyperestrogenemia, the presence of follicular cysts in the ovaries.The development of endometrial hypoplasia occurs against the background of an increase in glucose levels - by53.8 % (P < 0.001), total lipids - by 33.2 % (P < 0.01), progesterone - by 21.9 times (P < 0.001), with a decrease in indices of general resistance (serum bactericidal activity - by 23.9 % (P < 0.01), lysozyme activity - by 33.0 % (P < 0.01), leukocyte phagocytic activity - by 34.7 % (P < 0.01), estradiol content - by 2.54 times and cortisol - by 1.93 times (P < 0.001), indicating the development of hyperprogesteronemia and the presence of luteal cysts in the ovaries.