CURRENT STATUS OF EXTEMPORAL PRODUCTION OF MEDICINES IN THE FEDERAL REPUBLIC OF GERMANY
The article describes current state of pharmacy production in the Federal Republic of Germany (FRG). Data are given on the number of retail and hospital pharmacies, on the number of pharmaceutical personnel employed in pharmacy production; a number of prescription formulations in million units from 2017 to 2021. Legislative regulation of extemporal production is highlighted which, in addition to the European and German pharmacopoeias, is largely based on the national Code of Medicinal Products. Examples of standard and main prescriptions and technology of their production for such dosage forms as capsules, suppositories, creams, ointments and solutions are given. For soft dosage forms the most commonly used bases in the manufacture of medicines are indicated. General requirements for equipment and technology of solutions preparation for parenteral administration and ophthalmic drugs at a pharmacy are described. The reasons for expanding the range of extemporal medicines are highlighted (the use of ready-made medicinal forms, legalization of marijuana preparations for medicinal purposes, constant connection of pharmacies with the Central laboratory which tasks include operative consultation in case of difficulties in the preparation of medicines and their quality control).