Structure functional status ofgastric mucous tunic and it microbiocenosis on chronical gastritis at children
The purpose of the research is to estimate morphofunctional condition mucus-producing apparatus of gaster according to its microbiocenosis at chronic gastritis. The objects of the research were gastric biopsy materials from 55 children at the age from 7 to 15 with diagnosis chronic gastritis (CG) which were divided into two groups: the 1st group - 35 patients with Helicobacter pylori (H.pylori)-fssociated CG; the 2nd -20 patients with H.pylori-nonassociated CG. During the work there were used histologic, histochemical, lectinhistochemical, morphometric, bacteriologic and statistic methods. There was registered more evident recompartmentation of the lectin receptors on H.pylori-associated CG than on H.pylori-nonassociated CG, that was expressed by the elevation of the level of lectin connection by the cells having affinity to the Foucault mucins, and the reduction of the lectin receptors selectively reacting with the sialic acids (reduction of sialomucins's level) (p<0,05). It was found out that microbiocenosis disorders on H.pylori-associated CG and H.pylori-nonassociated CG have significant differences. Key words: chronic gastritis at children, lectinhistochemistry, microbiocenosis of gaster.