PHARMACOGNOSTIC STUDY ON SUBSTANTIATION OF MULTIPLE USING OF SILYBUM MARIANUM (L.) GAERTN
In the present paper the results of investigations on substantiation of multiple using of milk thistle [Silybum marianum (L.) Gaertn.] are discussed. As a result of the conducted research, the flagship approaches to produce soluble silymarin were studied. Perspective sorts of milk thistle [Silybum marianum (L.) Gaertn.] with the highest content of flavolignans were examined. The approaches to increase the bioavailability of silymar for inclusion in transdermal dosages forms were considered.