THE PATHOPHYSIOLOGICAL ASPECTS OF INFLUENCE WITH CHRONIC TOBACCO SMOKING ON MICROCIRCULATION SYSTEM
The aim of this study was investigate pathophysiological aspects of damages in microcirculation and endothelium-dependent vascular reactivity in patient with tobacco smoking. In this study take part 68 patients. The microcirculation was examined with method laser-Doppler flowmetry. We studied the amplitude-frequency characteristics, as well as conducted tests with vasoactive agents. Revealed that using of tobacco reduce the level of myogenic activity resistive precapillary microvessels and sphincters on 2,1 % (p p p p < 0,05).