Role of Ionized Calcium and Mechanical Stress in Controlling Mechanisms of Erythrocytes’ Cellular Properties
It was demonstrated that a mechanical stress of the erythrocyte membrane led to an entry of Са 2+ into cell if there is at least 50 μМ of Ca2+ concentration in suspending medium. In addition it was shown that modification of the erythrocytes cellular properties were determined by the increase of intracellular content of free calcium and activation of both receptor-operated and potential-dependent calcium channels of cell membrane. Taken together these data clarify an important role of Ca2+ in red blood cell mechanical property alterations.