THE POSSIBILITIES OF FAECAL TRANSFERRIN INVESTIGATION IN DIAGNOSTIC OF NSAID-INDUCED ENTEROPATHY
The aim of investigation was to estimate the diagnostic possibilities of faecal transferrin as indirect method or NSAID-induced enteropathy diagnostic. We were analyzed the transferrin level in faecus of 30 patients with osteoarthrosis with long anamnesis of treatment with NSAID (main group) and 20 patients with osteoarthrosis with occasional use of NSAID (comparative group). The sources of bleeding from upper and lower gastrointestinal tract were excluded. In patients of main group in 83,3 % the increase of faecal transferrin was estimated compared with only 5 % in comparative group (р = 0,001). The estimation of faecal transferrin is noninvasive safety method of indirect diagnostic of NSAID enteropathy.