THE EXPERIMENTAL AND CLINICAL SUBSTANTIATION OF USING MEDICINES FROM ARONIA MELANOCARPA FRUITS IN HYPERTENSION
The practice of the long-term application of synthetic medicines for treating hypertension has numerous facts of their insufficient therapeutic effectiveness because of their side effects, first of all. The problem of the antihypertensive pharmacotherapeutic complications is especially important in treating aged patients. The effective long-term pharmacotherapy for treating hypertension in such patients is possible only in the case of using plant medicines. One of the alternatives of such optimization for antihypertensive therapy is a medicine from aronia. Aronia fruits are used clinically in hypertension of the I-st and II-n stages. Clinical trials have proven that aronia fruit juice decreases BP in patients with hypertension of the I-st and II-n stages and has a positive effect on the patient’s general state in hypertension of the III-d stage and decreases the course of therapy. The use of aronia fruits in treating hypertension for decreasing BP is explained by the action of substances with P-vitamin activity, and the complex of polysaccharides from aronia leaves increases resistance and absorption of these natural polyphenolic substances.