Biologically Active Piperidin-Containing Mannich Bases
A review of the results of scientific research in the field of synthesis and study of the biologically active properties of piperidine-containing Mannich bases carried out in recent years is presented. The presence of high biological activity in aminomethoxy derivatives containing a piperidine fragment was shown. Some Mannich piperidine bases are reported to have high antibacterial activity against S.aureus, S.epidermidis, E.coli, K.pneumoniae, P.aeruginosa, S.typhi, Sh.flexneri and Pr.mirabilis, as well as antifungal activity against M.gypseum, M.canis, T.mentagrophytes, T.rubrum and C.albicans.