Use of a State Pharmacopoeia method to determine the microbiological purity of medicines containing live microorganisms
The microbiological purity determining method stated in the State Pharmacopoeia 12 th Edition for controlling the quality of medicines containing live microorganisms was assessed. Validation trials showed it possible to use a direct inoculation method to test the quality of probiotics by the index «Microbiological purity» and identified a group of drugs, the above methods for whose control needs to be further worked out.