Synthesis and Biological Activity of Monoterpenoids of Menthane Series
Antimycotic activity of monoterpenoids of menthane series and their thio derivatives obtained via the reaction of the corresponding monoterpenoids with thiols in the presence of Lewis acids was investigated. On the basis of (+)-1,2-oxide of limonene and methyl ester of mercaptoacetic acid in the presence of sodium methylate, an active antimycotic of the broad range of action was synthesized. The data on the toxicity of some monoterpenoids are reported.