Peroxisome proliferator-activated receptor gamma genes polymorphism (<i>PPARG)</i> as a marker for predisposition to sports
Purpose of the work is to find the molecular-genetic markers of Pro12 → Ala polymorphism of PPARG of hereditary predisposition to the manifestation of a high physical performance. During the work 122 athletes of different sports and 82 people who are not involved in sports were examined. The peculiarities of distribution of allele variants of PPARG gene in groups of athletes involved in different sports were obtained. It was found that a group of highly skilled athletes involved in sports with predominantly anaerobic nature of the energy PPARG Ala allele of the gene found in 11.1% more than the group of athletes involved in sports with mainly aerobic nature of the power supply. The existence of association between the Pro12 → Ala polymorphism of PPARG gene and predisposition to various sports activities was established