Kinetics <sup>99m</sup>Tc-MIBI in breast cancer according to the results of mathematical modeling
Objective: qualitative description of the kinetics of 99mTc-MIBI in the breast tumor to assess chemoresistance.Analysis of the kinetics of 99mTc-MIBI in breast tumors is according to mathematical modeling. The mathematical model shows that the main parameters mammostsintigrafy with 99mTc-MIBI to be considered for evaluation of tumor chemoresistance are effective tumor blood flow, rate of excretion radiopharmaceutical with cells, clearance of blood from the radiopharmaceutical, the level ofradiopharmaceutical washout from the tumor.