Dual-stage 18F-fluorocholine PET/CT scanning for biochemical recurrences of prostate cancer
PET/CT with 18F-fluorocholine, based on an assessment of phosphatidylcholine biodistribution, is an effective method in the diagnosis of bio- chemical recurrence of prostate cancer. According to results of our study on 71 patients (PSA level 1,775 (0.0245, 56.0975) ng/mL), the sensitivity of two-stage PET/CT with 18F-fluorocholine was 66.7 % (CI 55.3-780 %), and specificity - 80 % (CI 44.9-100.0 %), the over- all accuracy of the method ranged from 56.7 to 78.5 %. The results show the feasibility of two-staged PET/CT with 18F-fluorocholine in bio- chemical recurrence of prostate cancer.