Platelet aggregometry at brain infarct
The functional activity of platelet has been investigated in 20 patients at acute brain infarct (BI) by means of optical aggregometry with adenosine diphosphate of 0.5 and 2.0 |imol/l concentrations, collagen on the 1st day before treatment and 10th day after it. The hyperactivation of primary hemostasis was established in patients with BI which is displayed by nonreversible platelet aggregation and a significant increase of aggregometry parameters in comparison with the initial level. On the background of treatment, the optimization of blood aggregation is not observed because of the absence of a significant difference between parameters before treatment. Thus, the obtained results prove the necessity of monitoring the sensitivity of individual patients to antiplatelet therapy using optical aggregometry with a complex of inductors complex in secondary prevention of ischaemic strokes.