Study of immune system parameters and T-regulatory cells level at the patients suffering polypoid rhinosinusitis
The immune system condition at the patients suffering polypoid rhinosinusitis was investigated. The immune status and T-regulatory (CD45 + CD4 +CD25 + CD127 - ) cells level at 37 adults patients of both sexes were investigated by flow cytometry. The received data was compared to parametere of group of the pereons suffering from difficulties of nasal breathing is not associated with inflammatory diseases. Increase of eosinophils level in peripheral blood, decrease in ^regulato^ cells level, CD4/CD8 cells ratio and phagocytosis activity was revealed. These changes at the patients suffering polypoid rtiinosinusitis are specify proinflammatory reaction of immune system and decrease in mechanisms auto-tolerance, that unites pathogenesis polypoid rtiinosinusitis with rtieumatic and auto-immune diseases.