Remodeling of the left ventricular myocardium in patients with chronic kidney disease and arterial hypertension
Objective: The estimation of the causes of remodeling left ventricular myocardium among patients having arterial hypertension (AH) and chronic kidney disease. Methods: 98 patients having AH were examined. Hypertrophy of the left ventricular (LV) was diagnosed when LV myocardium mass index was more than 115 g/м2 for men and more than 95 g/м2 for women. The formula to estimate the speed of glomerular filtration CKD-EPI was used to define the degree of kidney dysfunction. Results: The signs of LV myocardial remodeling were observed among 43 patients having AH (43.8 %o). High prevalence of the obesity and hypertrophy of the left ventricular was observed among women (71.4 %o compared with 18.7 %o among men). Conclusions: LV myocardial hypertrophy is associated with the length of AH anamnesis. Hypertrophy unfavorable in terms of cardiovascular complications was more frequently registered as concentric. Also high prevalence of the chronic kidney disease in phases С2, С3а and C3b was observed among patients having AH. It increases the risk of unfortunate prognosis and requires active preventive measures and the correction of drug therapy to prevent fatal cardiovascular cases.