SECURITY OF THE VIRULENT FACTORS OF THE PSEUDOMONAS AERUGINOSA STRAINS, ACTIVATORS OF THE NOZOKOMIAL INFECTIONS
Pathogenicity at Pseudumonas aeruginosa is caused by the wide arsenal of virulent factors. One of the mechanisms dictating the expression of virulent factors is the phenomenon of cooperative sensitivity (Quorum Sensing) typical for P. aeruginosa. The characteristic of virulent factors of the P. aeruginosa strains is investigated by genotyping, circulating in ICU of a versatile hospital and their role in the opportunity of the development of intrahospital infections is appreciated. However, the polymorphism of the gene variants (virulent genes combination) does not allow to carry out effective and qualitative monitoring of the formation and circulation of the hospital strains and to reveal a source of an infection