Determination of a patient adaptation degree to a stress situation in pediatric dental practice
The study revealed that a local anaesthesia with inclusion of clonidine into 4% solution of articaine either with epinephrine (1:200000 or 1:400000) or without it proved adequate from point of view of stress adaptation enhancement. It has been determined that presence of clonidine in the anesthetic solution provides a synergism of peripheral and central a2-adrenomymetic action of clonidine, which from one hand allows to slow resorption of epinephrine into systemic circulation, and from the other hand to assist providing parasympathetic effect, thus reducing sympathetic effect of anaesthesia and operation stress. In its turn it increases stress adaptation for young patients and reduces risks of medical complications. Use of 4% articaine in combination with clonidine only is accompanied with its systemic effect, which in absence of epinephrine increases patients stress adaptation indexes through reduced sympathetic preoperative stress.