ABOUT REGULATION OF ATP-LEVEL IN UV-IRRADIATED LYMPHO-CYTES
Influence of UV-light (240-390 nm) in dozes 151 and 755 J/m2 on intensity of processes of lipid peroxidation, activity of Са2+-ATPase of plasma membrane and level of energy of lymphocytes of blood of donors in the presence and absence of autologous plasma was investigated. It was shown, that during incubation of UV-irradiated lympocytes at presence of plasma there is a decrease in intensity and light summ spontaneous luminol-dependent chemiluminescence, which is probably related to the protective antioxidant action of components of plasma. It was established, that change of activity Са2+-ATPase of plasma membrane of photomodified lymphocytes during their incubation is directed toward normalization of endo cellular concentration of Са2+. Due to this UV-irradiated lymphocytes getting ability to restoration of endo cellular level of ATP that reflects adaptive abilities of cells.