PILER INFLUENCE ON IMMUNE SYSTEM HUMORAL LINK AT DOSED BURNS BY OPEN FLAME
A burn traumatism is an important medical and social problem. Information about the mechanisms of the PILER influence on the immune system at rats with dosed burns is absent. Aim. To estimate character of violations of humoral link of immunity at the dosed burns by the open flame and find out PILER influence on it. Valid experimental model of dosed burn trauma by open flame was developed with possibility of adjusting of their basic parameters. Were used Bioptron-compact, which create the polarized light stream by the area 12,3 сm 2. Influence by the polarized light with part of infra-red radiation was carried out from distance to the skin 10 cm during 10 minutes three times per day. In the humoral link of the immune system in blood plasma determined the level of immunoglobulins (Ig) of classes A, М, and G and circulatory immune complexes. At the dosed burns by the open flame immunoglobulins changes showed the tendency of the Ig А gradual decline. The Ig G level showed the same tendency. The CIC level also increased sharply. In a week the Ig A level was large as compared to the rats of group of comparison. In a week the Ig G level was large as compared to the rats of group of comparison. The CIC level on the third and seventh days after a burn was lower as compared to the rats of group of comparison. Positive influence of the PILER on the humoral link of immunity with normalization of synthesis of the Ig class М was observed. Stimulation of synthesis of the Ig classes A and G and decline of the antigen loading with CIC elimination and antigens from a blood and modulation of autoimmune processes was observed.