The dynamics of aggregation property of thrombocytes of patients with incomplete variant of metabolic syndrome at the background of diuretic therapy
Purpose. To make valuation of effectiveness of correction of aggregative platelet activeness, in with an incomplete version of the metabolic syndrome with the help hydrochlorothiazide, verospiron. Materials and methods. Hydrochlorothiazide was prescribed to 28 patients for 16 weeks duration and verospiron was prescribed to 23 patients for 16 weeks duration. Dynamics of lipid blood spectrum, peroxide oxidation of lipids platelets, antioxidant protection of liquid part of blood and blood plates, and aggregative platelet activeness were valued. The results were worked out by Student′s criteria. Results. The usage of verospiron for with an incomplete version of the metabolic syndromepositively influences on peroxidation lipids, and optimizes platelet aggregation. Long-time usage of verospiron is able to fix the achieved effect. Gipotiazid does not reliably measured indicators worked on. Conclusion. For weight loosing in with an incomplete version of the metabolic syndrome it′s necessary to combine verospiron together with nonmedical ways of treatment.