What is (are) Tarsal carpal coalition syndrome ?
Tarsal carpal coalition syndrome is a genetic condition characterized by fusion of the bones in the wrist (carpals), feet (tarsals), and the fingers and toes (phalanges). Other bone abnormalities in the hands and feet may be present. Approximately 10 affected families have been described. Tarsal carpal coalition syndrome is caused by mutations in the NOD gene, and it is inherited in an autosomal dominant pattern.