What are the treatments for Hyper-IgD syndrome ?
How might hyper IgD syndrome be treated? There is no cure for hyper IgD syndrome and currently no established treatment.  Management is focused on supportive care. Some patients have responded to high-dose prednisone. Simvastatin, Anakinria (an IL-1 receptor antagonist) and TNF inhibitors have recently shown some success in controlling inflammatory attacks.   Consultations with the following specialists may be helpful: dermatologist, rheumatologist, and infectious disease specialist (to evaluate periodic fever).