How to diagnose Punctate palmoplantar keratoderma type I ?
How is punctate palmoplantar keratoderma type I diagnosed? Features that support the diagnosis of punctate palmoplantar keratoderma type I include a positive family history (i.e., other affected family members), the presence of multiple tiny hard rounded bumps of thickened skin on the hands and feet, and certain cell histology (i.e., appearance of skin samples when viewed under a microscope).