Medication is related to Depression. Depression can be Devastating. 
Employment is a synonym of Working. Working can cause/lead to Fatigue. Fatigue is related to Chronic. Chronic is a synonym of Continuing. 
Medication <--RelatedTo--> Depression --HasProperty--> Devastating 
Employment <--Synonym--> Working --Causes--> Fatigue <--RelatedTo--> Chronic <--Synonym--> Continuing 