Valid is related to Reasonable. Reasonable is the opposite of Remote. Remote is related to Pause. 
Toxic is related to Smoke. Smoke is related to Product. Product is related to Put. 
Valid <--RelatedTo--> Reasonable <--Antonym--> Remote <--RelatedTo--> Pause 
Toxic <--RelatedTo--> Smoke <--RelatedTo--> Product <--RelatedTo--> Put 