Profound is a synonym of Fundamental. Fundamental is related to Mass. Mass is related to Measure. 
Office is related to Bureau. Bureau is related to Department. Department is related to Organizational. 
Profound <--Synonym--> Fundamental <--RelatedTo--> Mass <--RelatedTo--> Measure 
Office <--RelatedTo--> Bureau <--RelatedTo--> Department <--RelatedTo--> Organizational 