Opening is a synonym of Slot. Slot is a type of Schedule. Schedule is related to Appointment. Appointment is related to Point. 
Nice is related to Last. Last is a type of Activity. Variation is a type of Activity. Variation is related to Combination. 
Opening <--Synonym--> Slot --IsA--> Schedule <--RelatedTo--> Appointment <--RelatedTo--> Point 
Nice <--RelatedTo--> Last --IsA--> Activity <--IsA-- Variation <--RelatedTo--> Combination 