Handle can be used for Manipulate. Handle is related to Mechanism. Mechanism is related to Bolt. Bolt can be used for Screw. 
Transit is a type of Bring. Bring is the opposite of Give. Give is related to Appoint. Appoint is related to Official. 
Manipulate <--UsedFor-- Handle <--RelatedTo--> Mechanism <--RelatedTo--> Bolt --UsedFor--> Screw 
Transit --IsA--> Bring <--Antonym--> Give <--RelatedTo--> Appoint <--RelatedTo--> Official 