Prison is related to Federal. Federal is similar to National. National is the opposite of Stranger. 
Strain is a type of Use. Strain is a type of Disease. Disease is related to Bacteria. 
Prison <--RelatedTo--> Federal <--SimilarTo--> National <--Antonym--> Stranger 
Use <--IsA-- Strain --IsA--> Disease <--RelatedTo--> Bacteria 