Manipulate is related to Drive. Tool is a type of Drive. Computer is a type of Tool. you are likely to find Software in/at/on Computer. 
Opening is a type of Motion. Opening is a synonym of Hole. 
Manipulate <--RelatedTo--> Drive <--IsA-- Tool <--IsA-- Computer <--AtLocation-- Software 
Motion <--IsA-- Opening <--Synonym--> Hole 