Opportunity is the opposite of Closed. Closed is a different concept from Open. 
Big is related to Bishop. Bishop can be used for Religion. Religion is related to Temple. Temple is related to Holy. 
Opportunity <--Antonym--> Closed <--DistinctFrom--> Open 
Big <--RelatedTo--> Bishop --UsedFor--> Religion <--RelatedTo--> Temple <--RelatedTo--> Holy 