Combination is a type of Collection. Hand is a type of Collection. Hand is related to Carry. 
Advantage is a type of Point. Point is related to Main. Main is related to Central. Central is related to Agency. 
Combination --IsA--> Collection <--IsA-- Hand <--RelatedTo--> Carry 
Advantage --IsA--> Point <--RelatedTo--> Main <--RelatedTo--> Central <--RelatedTo--> Agency 