Significant is a synonym of Pregnant. Pregnant is similar to Full. Full is related to Crowd. Crowd is related to Chaos. 
Beautiful is the opposite of Weak. Weakness is derived from Weak. Weakness is the opposite of Force. Force is related to Make. 
Significant <--Synonym--> Pregnant <--SimilarTo--> Full <--RelatedTo--> Crowd <--RelatedTo--> Chaos 
Beautiful <--Antonym--> Weak <--DerivedFrom-- Weakness <--Antonym--> Force <--RelatedTo--> Make 