Actual is related to Being. Being is the opposite of Poor. 
Science is related to Experiment. Experiment is a type of Inquiry. Inquiry is the opposite of Reply. Reply is related to Back. 
Actual <--RelatedTo--> Being <--Antonym--> Poor 
Science <--RelatedTo--> Experiment --IsA--> Inquiry <--Antonym--> Reply <--RelatedTo--> Back 