Appreciation is a type of Thanks. Bow is a type of Thanks. Bow is related to Shooting. Shooting is related to Arrow. 
Uncomfortable is the opposite of Comfortable. Comfortable is related to Familiar. Familiar is a synonym of Intimate. 
Appreciation --IsA--> Thanks <--IsA-- Bow <--RelatedTo--> Shooting <--RelatedTo--> Arrow 
Uncomfortable <--Antonym--> Comfortable <--RelatedTo--> Familiar <--Synonym--> Intimate 