Distribute is a type of Give. Give is the opposite of Resist. Resist is a type of React. Explode is a type of React. 
Headache is a synonym of Concern. Matter is a type of Concern. 
Distribute --IsA--> Give <--Antonym--> Resist --IsA--> React <--IsA-- Explode 
Headache <--Synonym--> Concern <--IsA-- Matter 