Ingredient is related to Oxygen. you are likely to find Oxygen in/at/on Plane. you are likely to find Alcohol in/at/on Plane. Alcohol is related to Liver. 
Cigarette is related to Cancer. Cancer is related to Disease. Suicide is a type of Disease. Suicide is a type of Killer. 
Ingredient <--RelatedTo--> Oxygen --AtLocation--> Plane <--AtLocation-- Alcohol <--RelatedTo--> Liver 
Cigarette <--RelatedTo--> Cancer <--RelatedTo--> Disease <--IsA-- Suicide --IsA--> Killer 