Reply is related to Remark. Remark is related to Excellent. Excellent is related to Better. Better is related to Quality. 
Disease is related to Disorder. Disorder is related to Chaos. Chaos is the opposite of Form. Form is a synonym of Cast. 
Reply <--RelatedTo--> Remark <--RelatedTo--> Excellent <--RelatedTo--> Better <--RelatedTo--> Quality 
Disease <--RelatedTo--> Disorder <--RelatedTo--> Chaos <--Antonym--> Form <--Synonym--> Cast 