Instruction is related to Explain. Explain is related to Explanation. 
you are likely to find Towel in/at/on Hotel. you are likely to find Toilet in/at/on Hotel. you are likely to find Toilet in/at/on Trash. you are likely to find Rubber in/at/on Trash. 
Instruction <--RelatedTo--> Explain <--RelatedTo--> Explanation 
Towel --AtLocation--> Hotel <--AtLocation-- Toilet --AtLocation--> Trash <--AtLocation-- Rubber 