Instrument is related to Music. Music is related to Cultural. 
Artificial is a different concept from Natural. Natural is related to Rock. Rock is the opposite of Suck. Lip can be used for Suck. 
Instrument <--RelatedTo--> Music <--RelatedTo--> Cultural 
Artificial <--DistinctFrom--> Natural <--RelatedTo--> Rock <--Antonym--> Suck <--UsedFor-- Lip 