Operate is a type of Manipulate. Operate is related to Control. Steer is a type of Control. 
Tighten is a synonym of Reduce. Reduce is a synonym of Contract. Muscle can Contract. 
Manipulate <--IsA-- Operate <--RelatedTo--> Control <--IsA-- Steer 
Tighten <--Synonym--> Reduce <--Synonym--> Contract <--CapableOf-- Muscle 