Limitation is a synonym of Prescription. Prescription is related to Drug. Acid is a type of Drug. 
Marker is related to Claim. Claim is a synonym of Require. Require is related to Help. 
Limitation <--Synonym--> Prescription <--RelatedTo--> Drug <--IsA-- Acid 
Marker <--RelatedTo--> Claim <--Synonym--> Require <--RelatedTo--> Help 