Confrontation is a synonym of Opposition. Opposition is the opposite of Consent. Consent is a synonym of Approve. Approve is a different concept from Decline. 
Interested is related to Care. Care is related to Emotion. Emotion is related to Sad. 
Confrontation <--Synonym--> Opposition <--Antonym--> Consent <--Synonym--> Approve <--DistinctFrom--> Decline 
Interested <--RelatedTo--> Care <--RelatedTo--> Emotion <--RelatedTo--> Sad 