you are likely to find Manager in/at/on Desk. Desk is related to Sit. Sit is related to Seat. 
Frame is a type of Framework. Frame is part of Picture. Picture is the opposite of Statue. Statue is related to Frozen. 
Manager --AtLocation--> Desk <--RelatedTo--> Sit <--RelatedTo--> Seat 
Framework <--IsA-- Frame --PartOf--> Picture <--Antonym--> Statue <--RelatedTo--> Frozen 