Mail is a type of Send. Route is a type of Send. 
Sport is related to Crowd. Crowd is related to Loud. Loud is a different concept from Whisper. Whisper is the opposite of Scream. 
Mail --IsA--> Send <--IsA-- Route 
Sport <--RelatedTo--> Crowd <--RelatedTo--> Loud <--DistinctFrom--> Whisper <--Antonym--> Scream 