Agent is related to Estate. Estate is related to Real. Real is related to Effective. Effective is a synonym of Efficient. 
Running can cause/lead to Sweat. Sweat is related to Cake. Cake is related to Pie. 
Agent <--RelatedTo--> Estate <--RelatedTo--> Real <--RelatedTo--> Effective <--Synonym--> Efficient 
Running --Causes--> Sweat <--RelatedTo--> Cake <--RelatedTo--> Pie 