Break is related to Pull. Pull is related to Sign. Sign is related to Instructional. 
Combined is a synonym of Joint. Wrist is a type of Joint. Wrist is the opposite of Ankle. 
Break <--RelatedTo--> Pull <--RelatedTo--> Sign <--RelatedTo--> Instructional 
Combined <--Synonym--> Joint <--IsA-- Wrist <--Antonym--> Ankle 