Bicycle is a synonym of Wheel. Wheel is related to Tire. Tire is a synonym of Fatigue. 
Biography is a type of Book. Profile is a type of Biography. Profile is related to User. Consumer is a type of User. 
Bicycle <--Synonym--> Wheel <--RelatedTo--> Tire <--Synonym--> Fatigue 
Book <--IsA-- Biography <--IsA-- Profile <--RelatedTo--> User <--IsA-- Consumer 