Flame is related to Famous. Famous is the opposite of Known. Known is the opposite of Guess. 
Guilt is part of Crime. Killing can be used for Crime. Murder is a type of Killing. 
Flame <--RelatedTo--> Famous <--Antonym--> Known <--Antonym--> Guess 
Guilt --PartOf--> Crime <--UsedFor-- Killing <--IsA-- Murder 