Courage is a synonym of Bottle. Split is a type of Bottle. 
Refuse is a synonym of Deny. Deny is the opposite of Permit. Trust is a type of Permit. Trust is related to Loyalty. 
Courage <--Synonym--> Bottle <--IsA-- Split 
Refuse <--Synonym--> Deny <--Antonym--> Permit <--IsA-- Trust <--RelatedTo--> Loyalty 