you are likely to find Notebook in/at/on Class. Sex is a type of Class. 
Frame is related to Structure. Structure is related to Order. Order is a synonym of Category. Category is related to Grain. 
Notebook --AtLocation--> Class <--IsA-- Sex 
Frame <--RelatedTo--> Structure <--RelatedTo--> Order <--Synonym--> Category <--RelatedTo--> Grain 