Establishment is a synonym of Appointment. Appointment is related to Schedule. 
Wildlife is related to Preserve. Preserve is related to Condition. Condition is related to Critical. Critical is a synonym of Significant. 
Establishment <--Synonym--> Appointment <--RelatedTo--> Schedule 
Wildlife <--RelatedTo--> Preserve <--RelatedTo--> Condition <--RelatedTo--> Critical <--Synonym--> Significant 