Killing can cause/lead to Investigation. Gun can be used for Killing. you are likely to find Gun in/at/on Desk. you are likely to find Report in/at/on Desk. 
Ruin is related to Total. Total is a type of Be. Person wants (to) Be. 
Investigation <--Causes-- Killing <--UsedFor-- Gun --AtLocation--> Desk <--AtLocation-- Report 
Ruin <--RelatedTo--> Total --IsA--> Be <--Desires-- Person 