While is a synonym of Effort. Struggle is a type of Effort. Struggle is related to Climb. Climb is related to Fun. 
Ruin is a type of Destruction. Ruin is related to Wilderness. 
While <--Synonym--> Effort <--IsA-- Struggle <--RelatedTo--> Climb <--RelatedTo--> Fun 
Destruction <--IsA-- Ruin <--RelatedTo--> Wilderness 