Popular is related to Main. Main is the opposite of Minor. Minor is the opposite of Severe. Severe is related to Wound. 
Employment is a synonym of Use. Use is a synonym of Convenience. 
Popular <--RelatedTo--> Main <--Antonym--> Minor <--Antonym--> Severe <--RelatedTo--> Wound 
Employment <--Synonym--> Use <--Synonym--> Convenience 