Document is related to Article. Article is related to Block. Block is a type of Area. 
Trace is a type of Indication. Mark is a type of Indication. Mark is a type of Evaluation. Evaluation is related to Investigation. 
Document <--RelatedTo--> Article <--RelatedTo--> Block --IsA--> Area 
Trace --IsA--> Indication <--IsA-- Mark --IsA--> Evaluation <--RelatedTo--> Investigation 