Which anesthetic agent can cause pain on IV adminis-tration?
(A) Ketamine (B) Propofol (C) Thiopentone (D) Midazolam
(B) Ans: B. Propofol(Ref: Miller 6/e p318-320: Morgan 4/e p200-202: Lee 13/e p158-160).Propofol:Oil-based preparation containing soyabean oil, egg lecithin & glycerol.As it contains oil - Hence painful injection IV administration.Should be preceded or mixed with lignocaine.