A patient was found to have splenomegaly, anemia and jaundice. All of the following is true about this condition except:
(A) Increased urobilinogen (B) Increased LDH (C) Decreased haptoglobin (D) Low reticulocyte count
(D) Ans: D. Low reticulocyte count(Ref: Robbins 9/e p 631, 632)A reactive increase in reticulocyte count occurs in hemolytic anemias due to increased erythropoiesis.Hemolytic anemia:Anemia & lowered tissue oxygen tension a Triggers erythropoietin production a Stimulates erythroid differentiation a Appearance of increased numbers erythroid precursors (normoblasts) in marrow. Compensatory increases in erythropoiesis a Resutls in reticulocytosis in peripheral blood.