Event of early acquisition of malignant phenotype of epithelium is an expression of:
(A) Cyclin a (B) Cyclin b (C) Cyclin c (D) Cyclin d
(D) Conclusion of this study was Deregulation of the p16/ pRb/cyclin DI pathway is an early event in acquisition of dysplasia, but deregulation of both pRb and p53 pathway is associated with malignant transformation and adverse prognosis in oral tumorigenesis.