Which of the following is true about prostate cancer?
(A) Histopathology is determined by Gleason score (B) Most common region involved is central zone (C) Most common type is squamous cell Carcinoma (D) It is not a hormone dependent cancer
(A) Prostate cancer: Adenocarcinoma Malignancy arising from gland Hormone dependent malignancy PROSTATE Ca. BREAST Ca.| |TESTOSTERONE PROGESTERONE - M/C malignant tumor in ? > 65 years- M/C site for malignancy - Peripheral zone Grading (Pathologic): GLEASON GRADE PRIMARY (1-5) SECONDARY (1-5) Gleason Score: Primary + secondary grading= 2-10 Screening: | Levels of PSA (prostate specific Antigen)- not specific