A neonate presented with jaundice on first day of life. His mother's blood group is `0' positive. How will you manage this patient?
(A) Observe only as it is mostly physiological jaundice (B) Exchange transfusion (C) Liver function tests and liver biopsy as it is mostly due to cholestasis (D) Phototherapy
(D) Ans: D. Phototherapy(Ref: Nelson 20/e p873)Jaundice on day 1 of life - Due to some hemolytic disease or congenital infections.Treated using phototherapy.Possibility of Rh incompatibility ruled out as mother blood group is 0+.Ideally basic investigations for hemolytic anemia should be sent simultaneously (not given in the option).Best option would be phototherapy.