What is the approved dose of misoprostol in emergent management of postpaum hemorrhage?
(A) 200 mcg (B) 400 mcg (C) 600 mcg (D) 1000 mcg
(C) Ans: C. 600 mcg(Ref Williams 24/e p785)Approved dose of misoprostol in emergent management of postpaum hemorrhage = 600 pg.Misoprostol:Derman (2006) compared a 600 pg oral dose given at delivery against placebo.Drug decreased hemorrhage incidence from 12 to 6 percent & severe hemorrhage from 1.2 to 0.2 percent.