Absorption of which of the following drugs is increased after a fatty meal?
(A) Amphotericin B (B) Griseofulvin (C) Ampicillin (D) Aspirin
(B) Ans: B. Griseofulvin (Ref: Goodman Gilman I2/e p1585; Katzung 13/e p632, 12/e p855,. KUT 7/e p790, 6/e p760)The oral administration of a 0.5 g dose of griseofulvin produces peak plasma concentrations of 1ug/mL in 4 hours.Improved drug absorption along with a fatty meal.Drug Absorption Reduced/Delayed by FoodDrug Absorption increased by foodAmpicillindegAspirindegAtenololdegAzithromycindegCaptoprildegCefaclorCephalexinCiprofloxacinDidanosineIndinavirdegIsoniazidaLoratidineNaficillinPenicillin G or VdegPhenobarbitaldegPhenytoindegRifampindegSucralfatedegTetracyclinedegDoxycyclinedegAtovaquonedegCarbamazepinedegChlohiazidedegCefuroximedegClofaziminedegDiazepamdegErythromycin GanciclovirdegHydrochlorothiazidedegItraconazoleaLithiumdegLovastatinMethylphenidateMetoprololdegNelfinavirNitrofurantoinPropranololdegPropoxypheneRitonavirdegSaquinavirdegSpironolactonedeg*Hydralazinedeg