Which of the following is the most common inherited malignancy :
(A) Infant leukemia (B) Retinoblastoma (C) Wilm's tumour (D) Neuroblastoma
(B) "Retinoblastoma is the most strking example of inhirited cancer syndrome. Approximately 40% of retinoblastomas are familial. Carrier of this gene have a 10000 fold increased risk of developing retinoblastoma usualy bilateral".


Each child of parent with familial bilateral retinoblastoam has a 50% risk of inheriting the retinoblastoma gene, of these 90% will develop retinoblastoma.