With respect to peripheral vascular disease, all of the following statements are true except:
(A) Ankle brachial index < 0.5 indicates critical limb ischemia (B) The ankle-brachial index is different at rest than that during exercise (C) L-arginine is useful for providing endothelium-independent vasorelaxation (D) Smoking has a greater association with peripheral vascular disease than coronary vascular disease
(D) Ans. d. Smoking has a greater association with peripheral vascular disease than coronary vascular disease > c. L-arginine is useful for providing endothelium-independent vasorelaxationSainston I9/e p/ 730; Schwaz 9/e p751, Bailey 26th/S75, 25th/900-902)Smoking has greater association with coronary aery disease than peripheral vascular disease. L-Arginine is a precursor of Nitric oxide so helps in vasodilation due to synthesis of NO by endothelium. Hence it is endothelium-dependent.