Which of the following is true for octreotide?
(A) Stimulates growth hormone secretion (B) Used in secretory diarrhea (C) Orally active (D) Contraindicated in acromegaly
(B) Ans. b. Used in secretory diarrhoea (Ref Goodman Gilman 12/e p1338-1339. 1346: Katling 11/e p650)Octreotide is used in secretory diarrheaOctreotide is an octapeptide analog of somatostatin, effective in inhibiting the severe secretory diarrhea brought about by hormone-secreting tumours of the pancreas and the GI tract."