Allergy in immediate perioperative period is due to:
(A) Opioids (B) LA agents (C) Induction agents (D) Neuromuscular blockers
(D) Ans: D. Neuromuscular blockers(Ref: Miller 7/e p884)Most common cause of perioperative anaphylaxis is muscle relaxants and antibiotics followed by opioids and intravenous anesthesia.Most Common Drugs Involved in Perioperative AnaphylaxisSubstanceMost commonly associatedMuscle relaxantsSuccinylcholine, rocuronium,atracuriumdegNatural rubber latexLatex gloves, tourniquets, Foley cathetersAntibioticsPenicillin & other beta-lactamsdegHypnoticsPropofol, thiopentaldegColloidsDextran, gelatindegOpioidsMorphine, meperidinedegOther substancesParacetamol, aprotinin,chymopapain, protamine,bupivacaine