Drug not given in PCOD in a 30-year-old lady with infeility?
(A) Clomiphene (B) Tamoxifen (C) OCPs (D) Metformin
(B) Ans: B. Tamoxifen(Ref: Jeffcott 6/e p205; Shaws 16/e p431-434, 15/e p371, 14/331-332, 13/353-354; Novak 's 15/e pl 076. Duna Gvnae 6/e p470)Drug not given in 30-year-old PCOD lady with infeility - Tamoxifen.Treatment of PCOD:Dexamethasone 0.5 mg at bedtime - Reduces androgen production.In Clomiphene failed group - Ovulation induced with FSH or GnRH analogues.DOC - Metformin - Treats root cause of PCOS, rectifies endocrine & metabolic functions and improves feility.Surgery (laparoscopic multiple puncture of cyst) - Reserved for failed medical therapy, hyperstimulation cases & GnRH analogue usage.