A patient with acute history of blistering and denudation involving >30% BSA along with erosions of the lips with hemorrhagic crusting and other mucosa for few days. What is the most common triggering factor?
(A) Bacterial infection (B) Viral infection (C) Drug induced (D) Idiopathic
(C) Lesions >30% BSA , erosion over lips and mucosa : Dx TEN TEN SJS: Haemorrhagic Crusting Sloughing of mucosa Targetoid lesion (2 rings) Nikolsky sign (Pseudo) due to epidermal necrosis. Epidermal necrosis (SJS/TEN) Etiology: Drugs: -Antiepileptic( MC) - CBZ, Lamotrigine * NSAIDS * Penicillin * Nevirapine CBZ induced SJS/TEN is a/w HLA B1502