Rotation speed of profile instruments
(A) 50-100 RPM (B) 100-3000 RPM (C) 300-500 RPM (D) 150-300 RPM
(D) Direct lines from Cohen: The recommended rotational speed for Profile instruments is 150 to 300 rpm, and to ensure a constant rpm level, the preferred means is electrical motors with gear reduction rather than air-driven motors.
Also know

The profile system was first sold as the "Series 29" hand instruments in .02 taper, but available in .04 and .06 taper
Tips of the Profile Series 29 rotary instruments - constant proportion of diameter increments (29%)

Profile instrument specifications
Cross sections: U-shape design with radial lands and a parallel central core
Lateral view: 20° helix angle, a constant pitch, and bullet shaped noncutting tips

Blades have Neutral or slightly negative rake angle
Acts like Reaming action on dentin rather than cutting