A Rh-negative mother, who has Indirect Coombs Test (ICT), negative was given Anti-D during 28 weeks of pregnancy. Which of the following is the ideal one?
(A) Give another dose of Anti-D 72 hours postpaum depending on the baby blood group (B) Give another dose of Anti-D 72 hours postpaum irrespective of baby blood group (C) No need of additional dose since she is ICT negative (D) All of the above
(A) Answer- A. Give another dose of Anti-D 72 hours postpaum depending on the baby blood groupACOG (2010) recommends anti-D immune globulin to be given prophylactically to all Rh D-negative, unsensitized women at approximately 28 weeks, and a second dose given after delivery if the infant is Rh D-positive. Before the 28-week dose of anti-D immune globulin, repeat antibocly screening is recommended to identify individuals who have become alloimmunized. Following delivery, anti-D immune globulin should be given within 72 hours.