A 50 years old male presented with frontal bossing, enlarged nasal bone, enlarged jaw and spade like fingers. Which of the following test will you do for diagnosis?
(A) IGF1 (B) ACTH (C) TSH (D) Serum coisol
(A) Answer- A. IGF1An IGF-I level provides a useful laboratory screening measure when clinical features raise the possibility of acromegaly.Acromegaly-Diagnosis:Screening investigation of choice in acromegaly: IGF-lConfirmatory & Gold standard: Oral Glucose Tolerance tests