Compared to unfractionated heparin, Low molecular weight heparin (LMWH) has reliable anticoagulant action because:
(A) It interferes with thrombin and antithrombin III simultaneously (B) It is less protein bound (C) It is given subcutaneously (D) It is cleared by macrophages
(B) Answer- B. It is less protein boundCompared to unfractionated heparin, Low molecular weight heparin (LMWH) has reliable anticoagulant action because it is less protein bound.Indications of LMW heparins:Prophylaxis of DVT and pulmonary embolism in high-risk patients undergoing surgery stroke or other immobilized patientsTreatment of established DVTUnstable anginaTo maintain patency of cannulae and shunts in dialysis patients and in extracorporeal circulation.