A 28 years old female presented with the history of recurrent aboions, pain in calves for 4 years. Patient is suffering from congenital deficiency of:
(A) Protein C (B) Thrombin (C) Plasmin (D) Factor XIII
(A) Answer- A (Protein C)'Inherited thrombophilia causes both early and late miscarriages due to intravascular thrombosis. Protein C resistance (factor V Leiden mutation) is the most common causeProtein C is the natural inhibitor or coagulation - Dutta