A diabetic and hypeensive patient taking several drugs presented with septicemia. Serum creatinine levels are 5.7 mg/dL. Which of the following drug should be stopped?
(A) Insulin (B) Metoprolol (C) Linagliptin (D) Metformin
(D) Serum creatinine levels are raised indicating renal failure. In renal failure and hepatic failure --> Metformin is C/I as it |ses the risk of developing lactic acidosis. Contraindicated in patients with an eGFR below 30 mL/minute/1.73 m2. eGFR should be measured annually for patients taking metformin therapy. eGFR is preferred over serum creatinine concentration to assess renal function for a person taking metformin therapy Linagliptin is a DPP-4 inhibitor. Metoprolol is a b blocker.