Angiotensin receptor blocker (ARB) with PPARgamma function as well is:
(A) Olmesaan (B) Candesaan (C) Telmisaan (D) Eprosaan
(C) Ans: C. Telmisaan(Ref: Yamagishi S, Takeuchi M. Telmisaan is a promising cardiornetabolic saan due to its unique PPAR-gamma-inducing propey. Med Hypotheses. 2005;64(3):476-8)Angiotensin receptor blocker (ARB) with PPAR-gamma function as well is telmisaan.Telmisaan:Act as a paial agonist of peroxisome prolilerator-activated receptor-gamma (PPAR-gamma).Due to its unique PPAR-gamma-modulating activity, telmisaan is a promising `cardiontetabolic saan', that targets both diabetes and CVD in hypeensive patients.The binding affinity to PPAR-gamma is highest for telmisaan followed by lisinopril and valsaan.