Black deposits on conjunctiva in a patient with glaucoma are seen with the use of:
(A) Prostaglandins (B) Carbonic anhydrase inhibitors (C) Epinephrine (D) Beta blocker
(C) Ans: C. Epinephrine(Ref: Goodman Gilman 12/e p286, 326; Katzung 13/e p161, 12/e p160; The Cornea by Smolin and Thoft's/p504)Black deposits on conjunctiva in a patient with glaucoma are seen with use of epinephrine. Latanoprost is associated with iris hyperpigmentation.Epinephrine is unstable in alkaline solution; when exposed to air or light, it turns pink from oxidation to adrenochrome and then brown from formation of polymers.