A 29-year-old, 4 months pregnant primigravida has history of juvenile myoclonic epilepsy. She has been regularly taking sodium valproate and now presents requesting for an opinion for a change in her anti-epileptic treatment. What would you sugeets her?
(A) Immediately taper off valproate and sta lamotrigine (B) Switch to carbamazepine (C) Continue valproate and serial drug monitoring in blood (D) Add lamotrigine to valproate
(C) Answer: c. Continue valproate and serial drug monitoring in blood (Ref Harrison I9/e p2544, 18/e p3269)Continue valproate with serial drug monitoring in the blood of the 4-month old patient having history of juvenile myoclonic epilepsy.