A child presented with Microcephaly, Hepatomegaly and periventricular calcification. Best site from where specimen should be obtained for diagnosis of CMV by PCR?
(A) Urine (B) Blood (C) Liver biopsy (D) CSF
(A) Congenital CMV infection C/F - Microcephaly Intracranial periventricular calcifications Chorioretinitis SNHL The diagnosis of congenital CMV infection is best confirmed by isolation of the virus from urine.