The genetic mutation seen in the most common type of maturity onset diabetes of young (MOM') is:
(A) Hepatocyte nuclear factor-4 (B) Hepatocyte nuclear factor-1 (C) Glucokinase (D) Insulin promoter factor-1
(B) Answer-b. Hepatocyte nuclear factor-1 Maturity onset Diabetes in Young (MODY) TypesMODY-1HNF-4 alphaMODY-2GlucokinaseMODY-3HNF-1 alpha (most common)MODY-4IPF-1MODY-5HNF-1 betaMODY-6NeuroD1/beta2