Biofilm forming bacteria causes antimicrobial resist-ance by all of the following except:
(A) Mechanical barrier (B) Increased excretion of antibiotics (C) Altered metabolism (D) Adherence
(D) Ans. d. AdherenceBiofilm in the bacteria leads antimicrobial resistance by acting as mechanical barrier, increased excretion of antibiotics and altered metabolism inside the biofilms.Growth in biofilms leads to altered microbial metabolism, production of extra cellular virulence factors, and decreased susceptibility to biocides, antimicrobial agents, and host defense molecules and cells. P aeruginosa growing on the bronchial mucosa during chronic infection, staphylococci and other pathogens growing on implanted medical devices, and dental pathogens growing on tooth surfaces to form plaque are several examples of microbial biofilm growth associated with human disease.