A 34-year-old primigravida at 11 weeks gestation presents to her obstetrics clinic with chief complain of exposure to a rash. Her husband is HIV+ve and has broken out on a rash in his left buttock which consists of a grouped vesicles on a maculopapular base, 4 days back. She has got her HIV testing done which is negative. Her P/R is 86/min, B/P = 100/60 mm of hg, resp rate 10/min and temp = 98.7F.FHS is heard via Doppler.What is the next step in the management:
(A) Administer high dose acyclovir to the infant at birth. (B) Administer high dose acyclovir to the patient now. (C) Administer varicella immunoglobulin to the infant at birth. (D) Administer varicella immunoglobulin to the patient
(D) DOC for treatment of pregnant mothers infected with chickenpox is i/v acyclovir
The pregnant woman is exposed to chickenpox rash, she does not have chickenpox…so obviously we will not treat her or her baby with acyclovir. Now since the female herself does not have chickenpox so why to give VZIG to the infant, rather this female should be given prophylactic VZIG so that she does not acquire chickenpox.

Varicella prophylaxis: Exposed pregnant women who are susceptible should be given Varicella IG within 96 hrs of exposure to prevent or attenuate varicella infection.