What is the difference between RIFLE & KDIGO criteria in differentiating a tubular injury?
(A) Uosm (B) Urinary Na (C) Urinary NGAL (D) FeNa (UN, x Scr / SNa x Ucr)
(C) Ans. C. Urinary NGALRIFLE originally used urinary sodium, urine osmolarity, FeNa to define tubular dysfunction/injury.Currently urinary NGAL/Kim-1/Cystatin C/L-FABP all are being evaluated as more sensitive and specific markers of tubular injury (KDIGO 2017/18).