What does low volume of distribution of a drug mean?
(A) Low bioavailability (B) Does not accumulates in tissues (C) Low absorption (D) Not metabolized in the body
(B) Ans: B. Does not accumulates in tissues(Ref: KDT 7/e p17, 18, 6/e p18)Low volume of distribution:Implies that the drug remains confined to the plasma compament without getting distributed in the body tissues.