Mutation seen in sickle cell anemia:
(A) Point (B) Inseion (C) Deletion (D) Frame shift
(A) Sickle-cell anemia Due to a single base alteration Point mutation Glutamate at the 6th position of b-chain of haemoglobin is replaced by Valine. UCA (serine) UCU (Serine) CCA (Proline) UAA (Stop codon) Silent mutation Mis-sense mutation Non sense Mutation