Peau d'orange in carcinoma breast is due to:
(A) Obstruction of sub-dermal lymphatics (B) Infiltration of Cooper's ligament (C) Hematogenous dissemination (D) Hematogenous dissemination
(A) Ans: A. Obstruction of sub-dermal lymphaticsPeau-d-orange is due to cutaneous lymphatic edema.Caused by obstruction of subdermal lymphatics. As the disease advances locally there may be skin involvement with peau d'orange or frank ulceration and fixation to the chest wall. This is described as cancer-en-cuirasse when the disease progresses around the chest wall.