16 year girl, Not sexually active, came for vaccination against cervical cancer. Which vaccine to be given
(A) Gardasil (B) Rubavac (C) Biovac (D) Tdap
(A) Quadrivalent Gardasil and the bivalent Cervarix against HPV subtypes 16 and 18. 97% to 100% efficacy for preventing cervical intraepithelial neoplasia (C1N) grades 2 and 3 caused by HPV 16 or 18 in females who were not previously infected However, efficacy was only 44% in those who were infected prior to vaccination. A third HPV vaccine, Gardasil-9, an additional five high-risk subtypes (HPV 31/33/45/52/58)