0_Wizard
Researchers have compared dog mutations to genetic changes in humans that trigger reduced intelligence. Looking at my dog, I can believe that.
New research seems to show that dogs have mutations to equivalent genetic regions in humans where changes are known to trigger high sociability and somewhat reduced intelligence.
chosen_Dog_0
Dog
chosen_topic_0_Dog
Carcinogenesis
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division. Cell division is a physiological process that occurs in almost all tissues and under a variety of circumstances. Normally the balance between proliferation and programmed cell death, in the form of apoptosis, is maintained to ensure the integrity of tissues and organs. According to the prevailing accepted theory of carcinogenesis, the somatic mutation theory, mutations in DNA and epimutations that lead to cancer disrupt these orderly processes by disrupting the programming regulating the processes, upsetting the normal balance between proliferation and cell death.
Dog
The domestic dog ("Canis lupus familiaris" or "Canis familiaris") is a member of the genus "Canis" (canines), which forms part of the wolf-like canids, and is the most widely abundant terrestrial carnivore. The dog and the extant gray wolf are sister taxa as modern wolves are not closely related to the wolves that were first domesticated, which implies that the direct ancestor of the dog is extinct. The dog was the first species to be domesticated and has been selectively bred over millennia for various behaviors, sensory capabilities, and physical attributes. Their long association with humans has led dogs to be uniquely attuned to human behavior and they are able to thrive on a starch-rich diet that would be inadequate for other canid species.
Origin of the domestic dog
The origin of the domestic dog is not clear. The domestic dog is a member of the genus "Canis", which forms part of the wolf-like canids, and is the most widely abundant terrestrial carnivore. The closest living relative of the dog is the extant gray wolf and there is no evidence of any other canine contributing to its genetic lineage. The dog and the extant gray wolf are sister taxa as modern wolves are not closely related to the wolves that were first domesticated. The archaeological record shows the first undisputed dog remains buried beside humans 14,700 years ago, with disputed remains occurring 36,000 years ago.
Evolution
Evolution is change in the heritable characteristics of biological populations over successive generations. Evolutionary processes give rise to biodiversity at every level of biological organisation, including the levels of species, individual organisms, and molecules. Repeated formation of new species (speciation), change within species (anagenesis), and loss of species (extinction) throughout the evolutionary history of life on Earth are demonstrated by shared sets of morphological and biochemical traits, including shared DNA sequences. These shared traits are more similar among species that share a more recent common ancestor, and can be used to reconstruct a biological "tree of life" based on evolutionary relationships (phylogenetics), using both existing species and fossils.
Evolution of the wolf
The evolution of the wolf occurred over a geologic time scale of 800 thousand years, transforming the first Middle Pleistocene wolf specimen that is recognized as being morphologically similar to "Canis lupus" into today's dog, dingo and gray wolf. Ecological factors including habitat type, climate, prey specialization and predatory competition has greatly influenced the wolf's genetic population structure and cranio-dental plasticity. Wolves went through a population bottleneck 20,000 years before present (YBP), which indicates that many wolf populations had gone extinct at a time that coincided with the Last Glacial Maximum and the expansion of modern humans worldwide with their technology for capturing large game.
Domestication of animals
The domestication of animals is the mutual relationship between animals with the humans who have influence on their care and reproduction. Charles Darwin recognized the small number of traits that made domesticated species different from their wild ancestors. He was also the first to recognize the difference between conscious selective breeding in which humans directly select for desirable traits, and unconscious selection where traits evolve as a by-product of natural selection or from selection on other traits. There is a genetic difference between domestic and wild populations. There is also such a difference between the domestication traits that researchers believe to have been essential at the early stages of domestication, and the improvement traits that have appeared since the split between wild and domestic populations.
Introduction to evolution
Evolution is the process of change in all forms of life over generations, and evolutionary biology is the study of how evolution occurs. Biological populations evolve through genetic changes that correspond to changes in the organisms' observable traits. Genetic changes include mutations, which are caused by damage or replication errors in organisms' DNA. As the genetic variation of a population drifts randomly over generations, natural selection gradually leads traits to become more or less common based on the relative reproductive success of organisms with those traits. The age of the Earth is about 4.54 billion years.
1_Apprentice
That's really interesting. Can you tell me more?
0_Wizard
The genetics of domestication is really interesting because we are able to choose desirable traits and breed specifically for them. Maybe we like our dogs dumb.
He was also the first to recognize the difference between conscious selective breeding in which humans directly select for desirable traits, and unconscious selection where traits evolve as a by-product of natural selection or from selection on other traits.
self_Domestication_of_animals_2
Domestication of animals
self_5_Domestication_of_animals
Origin of the domestic dog
The origin of the domestic dog is not clear. The domestic dog is a member of the genus "Canis", which forms part of the wolf-like canids, and is the most widely abundant terrestrial carnivore. The closest living relative of the dog is the extant gray wolf and there is no evidence of any other canine contributing to its genetic lineage. The dog and the extant gray wolf are sister taxa as modern wolves are not closely related to the wolves that were first domesticated. The archaeological record shows the first undisputed dog remains buried beside humans 14,700 years ago, with disputed remains occurring 36,000 years ago.
Domestication of animals
The domestication of animals is the mutual relationship between animals with the humans who have influence on their care and reproduction. Charles Darwin recognized the small number of traits that made domesticated species different from their wild ancestors. He was also the first to recognize the difference between conscious selective breeding in which humans directly select for desirable traits, and unconscious selection where traits evolve as a by-product of natural selection or from selection on other traits. There is a genetic difference between domestic and wild populations. There is also such a difference between the domestication traits that researchers believe to have been essential at the early stages of domestication, and the improvement traits that have appeared since the split between wild and domestic populations.
Domestication
Domestication is a sustained multi-generational relationship in which one group of organisms assumes a significant degree of influence over the reproduction and care of another group to secure a more predictable supply of resources from that second group. Charles Darwin recognized the small number of traits that made domestic species different from their wild ancestors. He was also the first to recognize the difference between conscious selective breeding in which humans directly select for desirable traits, and unconscious selection where traits evolve as a by-product of natural selection or from selection on other traits.
Genomics of domestication
Domesticated species and the human populations that domesticate them are typified by a mutualistic relationship of interdependence, in which humans have over thousands of years modified the genomics of domesticated species. Genomics is the study of the structure, content, and evolution of genomes, or the entire genetic information of organisms. Domestication is the process by which humans alter the morphology and genes of targeted organisms by selecting for desirable traits. Since domestication involves selection of traits over time, which leads to genetic changes, the science of genomics can identify which genes across an entire genome are altered during this intense artificial selection period.
Dmitry Belyayev (zoologist)
Dmitry Konstantinovich Belyayev (Russian: Дмитрий Константинович Беляев, 17 July 1917 – 14 November 1985) was a Russian geneticist and academician who served as director of the Institute of Cytology and Genetics (IC&G) of the USSR Academy of Sciences, Novosibirsk, from 1959 to 1985. His decades-long effort to breed domesticated foxes was described by "The New York Times" as “arguably the most extraordinary breeding experiment ever conducted.” A 2010 article in Scientific American stated that Belyayev “may be the man most responsible for our understanding of the process by which wolves were domesticated into our canine companions.”  Beginning in the 1950s, in order to uncover the genetic basis of the distinctive behavioral and physiological attributes of domesticated animals, Belyayev and his team spent decades breeding the wild silver fox ("Vulpes vulpes") and selecting for reproduction only those individuals in each generation that showed the least fear of humans.
Dog
The domestic dog ("Canis lupus familiaris" or "Canis familiaris") is a member of the genus "Canis" (canines), which forms part of the wolf-like canids, and is the most widely abundant terrestrial carnivore. The dog and the extant gray wolf are sister taxa as modern wolves are not closely related to the wolves that were first domesticated, which implies that the direct ancestor of the dog is extinct. The dog was the first species to be domesticated and has been selectively bred over millennia for various behaviors, sensory capabilities, and physical attributes. Their long association with humans has led dogs to be uniquely attuned to human behavior and they are able to thrive on a starch-rich diet that would be inadequate for other canid species.
Plant breeding
Plant breeding is the art and science of changing the traits of plants in order to produce desired characteristics. It has been used to improve the quality of nutrition in products for humans and animals. Plant breeding can be accomplished through many different techniques ranging from simply selecting plants with desirable characteristics for propagation, to methods that make use of knowledge of genetics and chromosomes, to more complex molecular techniques (see cultigen and cultivar). Genes in a plant are what determine what type of qualitative or quantitative traits it will have.The main purpose plant breeders is have is so they can create a specific outcome of plants and potentially new plant varieties.
1_Apprentice
I don't know I think dogs can be pretty smart....
0_Wizard
I actually agree. I have had very smart dogs as well. I really recommend researching the study of domesticating foxes. It is incredibly interesting and was a research project started by Dmitry Konstantivovich Belyayev
His decades-long effort to breed domesticated foxes was described by "The New York Times" as “arguably the most extraordinary breeding experiment ever conducted.” A 2010 article in Scientific American stated that Belyayev “may be the man most responsible for our understanding of the process by which wolves were domesticated into our canine companions.”  Beginning in the 1950s, in order to uncover the genetic basis of the distinctive behavioral and physiological attributes of domesticated animals, Belyayev and his team spent decades breeding the wild silver fox ("Vulpes vulpes") and selecting for reproduction only those individuals in each generation that showed the least fear of humans.
self_Dmitry_Belyayev_(zoologist)_1
Dmitry Belyayev (zoologist)
self_4_Dmitry_Belyayev_zoologist
Dmitry Belyayev (zoologist)
Dmitry Konstantinovich Belyayev (Russian: Дмитрий Константинович Беляев, 17 July 1917 – 14 November 1985) was a Russian geneticist and academician who served as director of the Institute of Cytology and Genetics (IC&G) of the USSR Academy of Sciences, Novosibirsk, from 1959 to 1985. His decades-long effort to breed domesticated foxes was described by "The New York Times" as “arguably the most extraordinary breeding experiment ever conducted.” A 2010 article in Scientific American stated that Belyayev “may be the man most responsible for our understanding of the process by which wolves were domesticated into our canine companions.”  Beginning in the 1950s, in order to uncover the genetic basis of the distinctive behavioral and physiological attributes of domesticated animals, Belyayev and his team spent decades breeding the wild silver fox ("Vulpes vulpes") and selecting for reproduction only those individuals in each generation that showed the least fear of humans.
Domesticated red fox
The Russian domesticated red fox is a domesticated form of the red fox ("Vulpes vulpes"). They are the result of an experiment which was designed to demonstrate the power of selective breeding to transform species, as described by Charles Darwin in "On the Origin of Species". The experiment was purposely designed to replicate the process that had produced dogs from wolves, by recording the changes in foxes, when in each generation only the most tame foxes were allowed to breed. In short order, the descendant foxes became tamer and more dog-like. The program was started in 1959 in the Soviet Union by zoologist Dmitry Belyayev and it has been in continuous operation since.
Silver fox (animal)
The silver fox(also known as a black fox) is a melanistic form of the red fox ("Vulpes vulpes"). Silver foxes display a great deal of pelt variation: some are completely black except for a white coloration on the tip of the tail, some are bluish-grey, and some may have a cinereous color on the sides. Historically, silver foxes were among the most valued furbearers, and their skins were frequently worn by nobles in Russia, Western Europe, and China. Wild silver foxes do not naturally reproduce exclusively with members of the same coat morph and can be littermates with the common red variety, though captive populations bred for their fur and as pets are almost exclusively mated with members of the same color.
Red fox
The red fox ("Vulpes vulpes") is the largest of the true foxes and one of the most widely distributed members of the order Carnivora, being present across the entire Northern Hemisphere from the Arctic Circle to North Africa, North America and Eurasia. It is listed as least concern by the IUCN. Its range has increased alongside human expansion, having been introduced to Australia, where it is considered harmful to native mammals and bird populations. Due to its presence in Australia, it is included among the list of the "world's 100 worst invasive species". The red fox originated from smaller-sized ancestors from Eurasia during the Middle Villafranchian period, and colonised North America shortly after the Wisconsin glaciation.
Pyotr Ilyich Tchaikovsky and the Belyayev circle
Pyotr Ilyich Tchaikovsky's relations with the group of composers known as the Belyayev circle, which lasted from 1887 until Tchaikovsky's death in 1893, influenced all of their music and briefly helped shape the next generation of Russian composers. This group was named after timber merchant Mitrofan Belyayev, an amateur musician who became an influential music patron and publisher after he had taken an interest in Alexander Glazunov's work. By 1887, Tchaikovsky was firmly established as one of the leading composers in Russia. A favorite of Tsar Alexander III, he was widely regarded as a national treasure.
Belyayev circle
The Belyayev circle () was a society of Russian musicians who met in Saint Petersburg, Russia between 1885 and 1908, and whose members included Nikolai Rimsky-Korsakov, Alexander Glazunov, Vladimir Stasov, Anatoly Lyadov, Alexander Ossovsky, Witold Maliszewski, Nikolai Tcherepnin, Nikolay Sokolov, Alexander Winkler among others. The circle was named after Mitrofan Belyayev, a timber merchant and amateur musician who became a music philanthropist and publisher after hearing the music of the teenage Glazunov. The Belyayev circle believed in a national style of classical music, based on the achievements of the composer group The Five which preceded it.
Pavel Belyayev
Pavel Ivanovich Belyayev (; 26 June 1925 – 10 January 1970), was a Soviet fighter pilot with extensive experience in piloting different types of aircraft. He was the first commander of the cosmonaut corps and the cosmonaut who commanded the historic Voskhod 2 mission which saw the first man walk in space in 1965. Pavel Belyayev was one of 6 children and was known as "Pasha" to his family and friends. He was born on 26 June 1925, in Chelishchevo, now Babushkinsky District, Vologda Oblast, Russia. In 1932 his family moved to the nearby village of Minkovo. His father was a physician's assistant and his mother worked on a collective farm.
1_Apprentice
That's interesting. Do you know why foxes?
0_Wizard
I am not really sure. They found a way to lessen their fear of humans.
His decades-long effort to breed domesticated foxes was described by "The New York Times" as “arguably the most extraordinary breeding experiment ever conducted.” A 2010 article in Scientific American stated that Belyayev “may be the man most responsible for our understanding of the process by which wolves were domesticated into our canine companions.”  Beginning in the 1950s, in order to uncover the genetic basis of the distinctive behavioral and physiological attributes of domesticated animals, Belyayev and his team spent decades breeding the wild silver fox ("Vulpes vulpes") and selecting for reproduction only those individuals in each generation that showed the least fear of humans.
partner_Dmitry_Belyayev_(zoologist)_1
Dmitry Belyayev (zoologist)
partner_3_Dmitry_Belyayev_zoologist
Nothing Records
Nothing Records was an American record label specializing in industrial rock and electronic music, founded by John Malm Jr. and Trent Reznor in 1992. It is considered an example of a vanity label, where an artist is able to run a label with some degree of independence from within a larger parent company—in this case, Interscope Records was the parent company. Nothing Records became largely defunct in 2004 due to a lawsuit by Reznor against John Malm. The label became inactive as a whole following several further releases—the "Beside You in Time" (February 2007) home video was the label's final release.
List of Agents of S.H.I.E.L.D. characters
"Agents of S.H.I.E.L.D." is an American television series created for ABC by Joss Whedon, Jed Whedon, and Maurissa Tancharoen, based on the Marvel Comics organization S.H.I.E.L.D. (Strategic Homeland Intervention, Enforcement and Logistics Division), a fictional peacekeeping and spy agency in a world of superheroes. It is set in the Marvel Cinematic Universe (MCU), sharing continuity with the feature and short films of the franchise. The series stars Clark Gregg, reprising his role of Phil Coulson from the films, as well as Ming-Na Wen, Brett Dalton, Chloe Bennet, Iain De Caestecker, and Elizabeth Henstridge.
List of Planet of the Apes characters
The "Planet of the Apes" franchise contains many characters that appear in one or more works. Caesar (birth name: Milo) is a fictional character in the ""Planet of the Apes" franchise". He is the leader and later ruler of the apes in both the original and the 2011 reboot series. He does not appear in the 2001 film. Caesar is the son of talking chimpanzees Cornelius and Zira. Originally named Milo after Dr. Milo, who travelled back in time with Cornelius and Zira to the Earth of Taylor's era, he was reared by his human foster father Armando, a traveling circus owner who gave Cornelius and Zira sanctuary when Zira went into labor in the final act of "Escape from the Planet of the Apes".
Dirawong
In Australian Aboriginal mythology of the Bundjalung Nation, the Dirawong, an unseen spiritual creature also known as the goanna spirit, is one of the Creator Beings of the Bundjalung Nation, that 1) Protects 2) Guards, 3) Battled the Rainbow Snake, and 4) Helps the people with;  'Aboriginal astronomy, body designs, bullroarers, bush cosmetics, bush foods, bush medicines, cave paintings and designs cut into trees, ceremonial headgear, ceremonial poles, cultural lore, dances, dreaming's, games, geographical locations, how people are required to behave in their communities, initiations, laws of community, paintings, rock art, rock engravings, rules for social behaviour, sacred chants, sacred earth mounds, sacred ground paintings, songlines, songs, stone artifacts, stone objects, stories, structures of society, symbols, technologies, the ceremonies performed in order to ensure continuity of life and land, values, wooden articles, wooden sacred objects, and also the beliefs, values, rules and practices concerning the peoples relationship to the land and water of Widje tribal territory within Bundjalung country.
2014 Aaron's 499
The 2014 Aaron's 499 was a NASCAR Sprint Cup Series stock car race run on May 4, 2014, at Talladega Superspeedway in Lincoln, Alabama. Contested over 188 laps on the tri-oval, it was the tenth race of the 2014 NASCAR Sprint Cup Series. Denny Hamlin won the race, his first points paying win at a restrictor plate track, and joined a list of drivers to win in their 300th start, while Greg Biffle finished second and Clint Bowyer, Brian Vickers, and A. J. Allmendinger rounded out the top five. The top rookies of the race were Kyle Larson (9th), Austin Dillon (15th), and Michael Annett (16th). This was the last race for the sponsor Aaron's  Joey Logano came from fourth on the final restart to win his second NASCAR Sprint Cup Series race of the season in the Toyota Owners 400 at Richmond International Raceway.
List of Supernatural characters
Supernatural is an American television drama series created by writer and producer Eric Kripke, and was initially broadcast by The WB. After its first season, The WB and UPN merged to form The CW, which is the current broadcaster for the show in the United States. The show features two main characters, Jared Padalecki as Sam Winchester and Jensen Ackles as Dean Winchester, brothers who travel across the country in a black 1967 Chevrolet Impala to hunt demons, supernatural creatures, and other paranormal entities, many of them based on folklore, myths, and American urban legends. In addition, "Supernatural" chronicles the relationship between the brothers and their father, John Winchester, as they seek to avenge and understand the murder of their mother at the hands of the demon Azazel.
Nandini (TV series)
Nandhini is an Indian multilingual supernatural television drama that premiered on 23 January 2017 on Sun TV, Gemini TV, Surya TV and Udaya TV channels. This is the first South Indian Serial to be aired in 4 South Indian language by Sun Network channels and same time except for Udaya TV, which is half hour earlier. It is claimed that the show is the second biggest budgeted series on Indian television after Naagin and the first in South India. Nithya Ram, Malavika Wales, Rahul Ravi and Adhitri are the main protagonists of the series. The series is produced by Tamil film director Sundar C. and his wife, actress Kushboo.