0_Wizard
Aging is a hard process. Dont ever get old! The process of becoming old is horrible
Ageing or aging (see spelling differences) is the process of becoming older.
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Ageing
chosen_topic_0_Ageing
2011 Alabama Crimson Tide football team
The 2011 Alabama Crimson Tide football team (variously "Alabama", "UA", "Bama" or "The Tide") represented the University of Alabama in the 2011 NCAA Division I FBS football season. It was the Crimson Tide's 117th overall and 78th season as a member of the Southeastern Conference (SEC) and its 20th within the SEC Western Division. The team was led by head coach Nick Saban, in his fifth year, and played their home games at Bryant–Denny Stadium in Tuscaloosa, Alabama. They finished the season with a record of twelve wins and one loss (12–1 overall, 7–1 in the SEC) and as consensus national champions.
List of films considered the worst
The films listed below have been cited by a variety of notable critics in varying media sources as being among the worst films ever made. Examples of such sources include Metacritic, Roger Ebert's list of most-hated films, "The Golden Turkey Awards", "Leonard Maltin's Movie Guide", Rotten Tomatoes, the Stinkers Bad Movie Awards, "Mystery Science Theater 3000", and the Golden Raspberry Awards ("Razzies"). "Reefer Madness" (originally released as "Tell Your Children" and sometimes titled or subtitled as "The Burning Question", "Dope Addict", "Doped Youth", and "Love Madness") is a 1936 American exploitation film and propaganda work revolving around the melodramatic events that ensue when high school students are lured by pushers to try marijuana—from a hit and run accident, to manslaughter, suicide, attempted rape, and descent into madness.
Senescence
Senescence () or biological aging (also spelled biological ageing) is the gradual deterioration of function characteristic of most complex lifeforms, arguably found in all biological kingdoms, that on the level of the organism increases mortality after maturation. The word "senescence" can refer either to cellular senescence or to senescence of the whole organism. It is commonly believed that cellular senescence underlies organismal senescence. The science of biological aging is biogerontology. Senescence is not the inevitable fate of all organisms and can be delayed. The discovery, in 1934, that calorie restriction can extend lifespan by 50% in rats, and the existence of species having negligible senescence and potentially immortal species such as "Hydra", have motivated research into delaying and preventing senescence and thus age-related diseases.
Horrible Histories (book series)
Horrible Histories is a series of illustrated history books published in the United Kingdom by Scholastic, and part of the Horrible Histories franchise. They are designed to engage children in history by presenting the unusual, gory, or unpleasant aspects in a tongue-in-cheek manner in contrast to the formality of lessons taught in school. The books are written by Terry Deary, Peter Hepplewhite and Neil Tonge and illustrated by Martin Brown, Mike Phillips, Phillip Reeve, and Kate Sheppard. The first titles in the series, "The Terrible Tudors" and "The Awesome Egyptians", were published in June 1993.
DONT
In the card game contract bridge, DONT is a conventional overcall used to interfere with an opponent's one notrump (1NT) opening bid. DONT, an acronym for Disturb Opponents' Notrump, was designed by Marty Bergen, and is therefore also referred to as "Bergen over Notrump". Although the method is often criticized for being too nebulous, it remains fairly popular. The convention was first published in the September/October 1989 issue of "Bridge Today". In DONT, the two-level overcalls of trump show a two suiter of the suit bid and an unspecified higher-ranking suit. The feature distinguishing DONT from other similar conventions such as Cappelletti is the use of the double to show length in one suit, rather than hand strength or for .
Evolution of ageing
Enquiry into the evolution of ageing aims to explain why survival, reproductive success, and functioning of almost all living organisms decline at old age. Leading hypotheses suggest that a combination of limited resources, and an increasing risk of death by environmental causes determine an "optimal" level of self-maintenance, i.e. the repair of molecular and cellular level damage that accumulates over time. Allocation of limited resources into such damage repair is traded-off with investment into reproduction, which determines the individual's Darwinian fitness. In consequence, traits that improve an individual's performance in early life are favored by selection, even if the same traits have negative effects late in life, when the individual has already passed on their genes to the next generation.
Gerontology
Gerontology is the study of the social, cultural, psychological, cognitive, and biological aspects of aging. The word was coined by Ilya Ilyich Mechnikov in 1903, from the Greek γέρων, "geron", "old man" and -λογία, "-logia", "study of". The field is distinguished from geriatrics, which is the branch of medicine that specializes in the treatment of existing disease in older adults. Gerontologists include researchers and practitioners in the fields of biology, nursing, medicine, criminology, dentistry, social work, physical and occupational therapy, psychology, psychiatry, sociology, economics, political science, architecture, geography, pharmacy, public health, housing, and anthropology.
1_Apprentice
Aging is definitely tough, unfortunately I am already old, lol.
0_Wizard
That is unfortunate! Reaction time is something that goes with age also, but a positive with aging is that we become wiser
Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand.
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Ageing
chosen_topic_0_Ageing
Mental chronometry
Mental chronometry is the use of response time in perceptual-motor tasks to infer the content, duration, and temporal sequencing of cognitive operations. Mental chronometry is one of the core paradigms of experimental and cognitive psychology, and has found application in various disciplines including cognitive psychophysiology, cognitive neuroscience, and behavioral neuroscience to elucidate mechanisms underlying cognitive processing. Mental chronometry is studied using measurements of reaction time (RT), which is the elapsed time between the presentation of a sensory stimulus and the subsequent behavioral response.
J.P. Wiser's Whisky
J.P. Wiser's Whisky is Canada's oldest continuously produced Canadian whisky. The brand was established in 1857, and Hiram Walker & Sons Limited currently produces it at their Windsor, Ontario, distillery. Since 1935, they have been the majority shareholder of Corby Spirit and Wine. Both companies came into ownership of international liquor company Pernod Ricard in 2005. John Philip (J.P.) Wiser was born in 1825 in New York. He was the son of Isaac J. Wiser and Mary Egert. In 1857, Wiser began running the Charles Payne Distillery and Farm in Prescott, Ontario, which was owned by his uncle, Charles Egert, and his uncle's business partner, Amos Averell.
Aging movement control
Normal aging movement control in humans is about the changes in the muscles, motor neurons, nerves, sensory functions, gait, fatigue, visual and manual responses, in men and women as they get older but who do not have neurological, muscular (atrophy, dystrophy...) or neuromuscular disorder. With aging, neuromuscular movements are impaired, though with training or practice, some aspects may be prevented. For voluntary force production, action potentials occur in the cortex. They propagate in the spinal cord, the motor neurons and the set of muscle fibers they innervate. This results in a twitch which properties are driven by two mechanisms: motor unit recruitment and rate coding.
Bracket racing
Bracket racing is a form of drag racing that allows for a handicap between predicted elapsed time of the two cars over a standard distance, typically within the three standard distances (1/8 mile, 1,000 foot, or 1/4 mile) of drag racing. The effect of the bracket racing rules is to place a premium on consistency of performance of the driver and car rather than on raw speed, which in turn makes victory much less dependent on large infusions of money, and more dependent on mechanical and driving skill, such as reaction times, shifting abilities, and ability to control the car. Therefore, bracket racing (using the aforementioned handicapping system) is popular with casual weekend racers.
Visual search
Visual search is a type of perceptual task requiring attention that typically involves an active scan of the visual environment for a particular object or feature (the target) among other objects or features (the distractors). Visual search can take place with or without eye movements. The ability to consciously locate an object or target amongst a complex array of stimuli has been extensively studied over the past 40 years. Practical examples of using visual search can be seen in everyday life, such as when one is picking out a product on a supermarket shelf, when animals are searching for food amongst piles of leaves, when trying to find your friend in a large crowd of people, or simply when playing visual search games such as "Where's Wally?"
The Spirit of the Age
The Spirit of the Age (full title "The Spirit of the Age: Or, Contemporary Portraits") is a collection of character sketches by the early 19th century English essayist, literary critic, and social commentator William Hazlitt, portraying 25 men, mostly British, whom he believed to represent significant trends in the thought, literature, and politics of his time. The subjects include thinkers, social reformers, politicians, poets, essayists, and novelists, many of whom Hazlitt was personally acquainted with or had encountered. Originally appearing in English periodicals, mostly "The New Monthly Magazine" in 1824, the essays were collected with several others written for the purpose and published in book form in 1825.
Hick's law
Hick's law, or the Hick–Hyman law, named after British and American psychologists William Edmund Hick and Ray Hyman, describes the time it takes for a person to make a decision as a result of the possible choices he or she has: increasing the number of choices will increase the decision time logarithmically. The Hick–Hyman law assesses cognitive information capacity in choice reaction experiments. The amount of time taken to process a certain amount of bits in the Hick–Hyman law is known as the "rate of gain of information". Hick's law is sometimes cited to justify menu design decisions. For example, to find a given word (e.g.
1_Apprentice
I can see that.  My eyesight is the worst thing to go, so far.
0_Wizard
Theres something called programmed ageing. It sounds pretty interesting, do you know anything about it?
Programmed ageing should not be confused with programmed cell death (apoptosis).
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Ageing
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Evolution of ageing
Enquiry into the evolution of ageing aims to explain why survival, reproductive success, and functioning of almost all living organisms decline at old age. Leading hypotheses suggest that a combination of limited resources, and an increasing risk of death by environmental causes determine an "optimal" level of self-maintenance, i.e. the repair of molecular and cellular level damage that accumulates over time. Allocation of limited resources into such damage repair is traded-off with investment into reproduction, which determines the individual's Darwinian fitness. In consequence, traits that improve an individual's performance in early life are favored by selection, even if the same traits have negative effects late in life, when the individual has already passed on their genes to the next generation.
The Face in the Frost
The Face in the Frost is a short 1969 fantasy novel by author John Bellairs. Unlike most of his later works, this book is meant for adult readers. It centers on two accomplished wizards, Prospero ("and not the one you're thinking of") and Roger Bacon, tracking down the source of a great magical evil. The subject matter prompted Ursula K. Le Guin to say of the novel, ""The Face in the Frost" takes us into pure nightmare before we know it—and out the other side." This novel was listed in the "recommended reading" list in the first edition "Advanced Dungeons and Dragons" "Dungeon Master's Guide" by Gary Gygax.
Ageing
Ageing or aging (see spelling differences) is the process of becoming older. The term refers especially to human beings, many animals, and fungi, whereas for example bacteria, perennial plants and some simple animals are potentially immortal. In the broader sense, ageing can refer to single cells within an organism which have ceased dividing (cellular senescence) or to the population of a species (population ageing). In humans, ageing represents the accumulation of changes in a human being over time, encompassing physical, psychological, and social changes. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand.
Little Star (novel)
Little Star () is a 2010 horror/drama novel written by John Ajvide Lindqvist. It is named after "Lilla stjärna", the Swedish entry to the Eurovision Song Contest 1958 held in Hilversum, the Netherlands. In 1992, a musician named Lennart finds in the woods an infant left for dead. He takes her to his wife, Laila, and the two raise the child in secrecy, believing that her catatonic and trance-like state will result in her being perceived as mentally ill. Their adult son, Jerry, frequently visits the child, whom he names Theres. Lennart becomes obsessed with Theres due to her angelic voice. He convinces her never to leave the house by telling her that the world is full of "big people" who want to eat up the "little people," like her.
List of Daredevil characters
"Daredevil" is an American web television series created for Netflix by Drew Goddard, based on the Marvel Comics character of the same name. It is set in the Marvel Cinematic Universe (MCU), sharing continuity with the films of the franchise, and is the first in a series of shows that will lead up to a Defenders crossover miniseries. The series stars Charlie Cox as Matt Murdock / Daredevil, as well as Deborah Ann Woll, Elden Henson, Rosario Dawson, and Vincent D'Onofrio. Toby Leonard Moore, Vondie Curtis-Hall, Bob Gunton, and Ayelet Zurer join them for the first season, while Jon Bernthal, Élodie Yung, and Stephen Rider join them for the second.
Nothing Records
Nothing Records was an American record label specializing in industrial rock and electronic music, founded by John Malm Jr. and Trent Reznor in 1992. It is considered an example of a vanity label, where an artist is able to run a label with some degree of independence from within a larger parent company—in this case, Interscope Records was the parent company. Nothing Records became largely defunct in 2004 due to a lawsuit by Reznor against John Malm. The label became inactive as a whole following several further releases—the "Beside You in Time" (February 2007) home video was the label's final release.
Nandini (TV series)
Nandhini is an Indian multilingual supernatural television drama that premiered on 23 January 2017 on Sun TV, Gemini TV, Surya TV and Udaya TV channels. This is the first South Indian Serial to be aired in 4 South Indian language by Sun Network channels and same time except for Udaya TV, which is half hour earlier. It is claimed that the show is the second biggest budgeted series on Indian television after Naagin and the first in South India. Nithya Ram, Malavika Wales, Rahul Ravi and Adhitri are the main protagonists of the series. The series is produced by Tamil film director Sundar C. and his wife, actress Kushboo.
1_Apprentice
My eyesight going is the worst for me, so far.
0_Wizard
Ageing pretty much just means single cells of a human or animal have stopped dividing.
In the broader sense, ageing can refer to single cells within an organism which have ceased dividing (cellular senescence) or to the population of a species (population ageing).
chosen_Ageing_0
Ageing
chosen_topic_0_Ageing
Ageing
Ageing or aging (see spelling differences) is the process of becoming older. The term refers especially to human beings, many animals, and fungi, whereas for example bacteria, perennial plants and some simple animals are potentially immortal. In the broader sense, ageing can refer to single cells within an organism which have ceased dividing (cellular senescence) or to the population of a species (population ageing). In humans, ageing represents the accumulation of changes in a human being over time, encompassing physical, psychological, and social changes. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand.
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells. In bacteria, which lack a cell nucleus, the cell cycle is divided into the B, C, and D periods. The B period extends from the end of cell division to the beginning of DNA replication. DNA replication occurs during the C period. The D period refers to the stage between the end of DNA replication and the splitting of the bacterial cell into two daughter cells. In cells with a nucleus, as in eukaryotes, the cell cycle is also divided into three periods: interphase, the mitotic (M) phase, and cytokinesis.
Hayflick limit
The Hayflick limit or Hayflick phenomenon is the number of times a normal human cell population will divide until cell division stops. Empirical evidence shows that the telomeres associated with each cell's DNA will get slightly shorter with each new cell division until they shorten to a critical length. The concept of the Hayflick limit was advanced by American anatomist Leonard Hayflick in 1961, at the Wistar Institute in Philadelphia, Pennsylvania, USA. Hayflick demonstrated that a population of normal human fetal cells in a cell culture will divide between 40 and 60 times. The population will then enter a senescence phase, which refutes the contention by Nobel laureate Alexis Carrel that normal cells are immortal.
Evolution of ageing
Enquiry into the evolution of ageing aims to explain why survival, reproductive success, and functioning of almost all living organisms decline at old age. Leading hypotheses suggest that a combination of limited resources, and an increasing risk of death by environmental causes determine an "optimal" level of self-maintenance, i.e. the repair of molecular and cellular level damage that accumulates over time. Allocation of limited resources into such damage repair is traded-off with investment into reproduction, which determines the individual's Darwinian fitness. In consequence, traits that improve an individual's performance in early life are favored by selection, even if the same traits have negative effects late in life, when the individual has already passed on their genes to the next generation.
List of Tenchi Muyo! characters
The following is a list of the major characters from the anime and manga series "Tenchi Muyo! Ryo-Ohki" and its spin-offs "Tenchi Muyo! GXP", "Tenchi Muyo! War on Geminar", "Tenchi Universe", "Tenchi in Tokyo", "Ai Tenchi Muyo! ", "", "Magical Project S", and "Magical Girl Pretty Sammy". Masaki Kajishima and Hiroki Hayashi, who both worked on the "Bubblegum Crisis" OAVs, cite the show as being the inspiration for "Tenchi Muyo! Ryo-Ohki". In an interview with AIC, Hayashi described "Bubblegum Crisis" as "a pretty gloomy anime. Serious fighting, complicated human relationships, and dark Mega Tokyo."
Acoustic tweezers
Acoustic tweezers is a technology that is able to control the movement of objects by sound waves. In a standing acoustic field, objects will experience an acoustic radiation force that moves the objects to special regions of the acoustic field. Depending on the properties (density, compressibility) of the objects, they can be moved to either acoustic pressure nodes (minimum pressure regions) or pressure antinodes (maximum pressure regions). As a result, precise manipulation of objects using sound waves is feasible by controlling the position of pressure nodes. Acoustic tweezers does not require expensive equipment and complex experimental setups.
Induced stem cells
Induced stem cells (iSC) are stem cells derived from somatic, reproductive, pluripotent or other cell types by deliberate epigenetic reprogramming. They are classified as either totipotent (iTC), pluripotent (iPSC) or progenitor (multipotent—iMSC, also called an induced multipotent progenitor cell—iMPC) or unipotent—(iUSC) according to their developmental potential and degree of dedifferentiation. Progenitors are obtained by so-called direct reprogramming or directed differentiation and are also called induced somatic stem cells. Three techniques are widely recognized:  In 1895 Thomas Morgan removed one of a frog's two blastomeres and found that amphibians are able to form whole embryos from the remaining part.