0_Apprentice
Do you know anything about depression in people? 
1_Wizard
Depression is rough for sure -- I have personal experience with it. It can actually be a symptom of some diseases or a side effect of some drugs.
0_Apprentice
I experienced it after taking a very strong antibiotic. I didn't know that could happen! 
1_Wizard
How did you feel? There's such a wide range of effects -- sadness, anxiety, emptiness, hopelessness...