0_Wizard
I learned recently that dogs have been found to have mutations that are equivalent to a genetic mutation in humans that would make a person more sociable and less intelligent.
New research seems to show that dogs have mutations to equivalent genetic regions in humans where changes are known to trigger high sociability and somewhat reduced intelligence.
chosen_Dog_0
Dog
chosen_topic_0_Dog
Evolution of the wolf
The evolution of the wolf occurred over a geologic time scale of 800 thousand years, transforming the first Middle Pleistocene wolf specimen that is recognized as being morphologically similar to "Canis lupus" into today's dog, dingo and gray wolf. Ecological factors including habitat type, climate, prey specialization and predatory competition has greatly influenced the wolf's genetic population structure and cranio-dental plasticity. Wolves went through a population bottleneck 20,000 years before present (YBP), which indicates that many wolf populations had gone extinct at a time that coincided with the Last Glacial Maximum and the expansion of modern humans worldwide with their technology for capturing large game.
Origin of the domestic dog
The origin of the domestic dog is not clear. The domestic dog is a member of the genus "Canis", which forms part of the wolf-like canids, and is the most widely abundant terrestrial carnivore. The closest living relative of the dog is the extant gray wolf and there is no evidence of any other canine contributing to its genetic lineage. The dog and the extant gray wolf are sister taxa as modern wolves are not closely related to the wolves that were first domesticated. The archaeological record shows the first undisputed dog remains buried beside humans 14,700 years ago, with disputed remains occurring 36,000 years ago.
Evolution
Evolution is change in the heritable characteristics of biological populations over successive generations. Evolutionary processes give rise to biodiversity at every level of biological organisation, including the levels of species, individual organisms, and molecules. Repeated formation of new species (speciation), change within species (anagenesis), and loss of species (extinction) throughout the evolutionary history of life on Earth are demonstrated by shared sets of morphological and biochemical traits, including shared DNA sequences. These shared traits are more similar among species that share a more recent common ancestor, and can be used to reconstruct a biological "tree of life" based on evolutionary relationships (phylogenetics), using both existing species and fossils.
Frameshift mutation
A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three. Due to the triplet nature of gene expression by codons, the insertion or deletion can change the reading frame (the grouping of the codons), resulting in a completely different translation from the original. The earlier in the sequence the deletion or insertion occurs, the more altered the protein. A frameshift mutation is not the same as a single-nucleotide polymorphism in which a nucleotide is replaced, rather than inserted or deleted.
Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements. Mutations result from errors during DNA replication or other types of damage to DNA (such as may be caused by exposure to radiation or carcinogens), which then may undergo error-prone repair (especially microhomology-mediated end joining), or cause an error during other forms of repair, or else may cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements.
BRCA mutation
A "BRCA" mutation is a mutation in either of the "BRCA1" and "BRCA2" genes, which are tumour suppressor genes. Hundreds of different types of mutations in these genes have been identified, some of which have been determined to be harmful, while others have no proven impact. Harmful mutations in these genes may produce a hereditary breast-ovarian cancer syndrome in affected persons. Only 5-10% of breast cancer cases in women are attributed to "BRCA1" and "BRCA2" mutations (with "BRCA1" mutations being slightly more common than "BRCA2" mutations), but the impact on women with the gene mutation is more profound.
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they may have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity, and excessive drinking of alcohol.
1_Apprentice
I read about that too.  I wonder why that is?