I am a 36 year old SAHschoolingM of 3 little ones 7 and under and have had back problems, pain and lower extremity pain since I was very small due to JRA and now Fibromyalgia.  I don't have weight issues, my weight is in a healthy range, though a loss of 5lb. would not be unwelcome.  I am not as active as I was when I was younger and I would like to change that, but I have many bad days and it's hard to be fit when you feel bad.  I pretty much only wear Dansko's and Birkenstocks if I want to eliminate daily debilitating pain, and even then some days I just can't function normally.
I want some shoes to wear when I am being more athletic with my family.  I haven't really found any in the past that support me like my Dansko's and Birks and allow me to be relatively pain free all day.
I am trying out these shoes due to other customer rave reviews and will come back and update once I've worn them a bit.
I purchased these today and wore them as I did house work and errands for several hours until they started to be uncomfortable.  They took a bit of getting used to, Dansko's however have a rocker sole so that wasn't the worst of it.  I found that when I walked and was standing still there was more "play" in my ankles and I had to use more muscles to stand still.  Overall they were comfortable and I am looking forward to getting used to them.
After taking them off I can definitely feel muscle fatigue like I just completed a workout.  It isn't a bad feeling though.
The sales person where I purchased them has been selling shoes for over 30 years, and himself suffered with back and knee pain.  He reported wearing these daily for 3 months, with no breakdown, and relief of his issues once he completed the break in period.  I am skeptical because he is after all a sales man.  But hopeful because I need some athletic shoes that don't make me have worse problems than I already have.
eta 7/28/10
After over a week of wearing these on and off, I cannot say that they are as comfortable or supportive as my Dansko clogs or Birkenstocks, but they haven't created any new problems, and for me that is very good.  They are working out for me better than many other athletic style shoes I have bought in the past.  I replaced the insole with a Dr. Scholls back relief insole the first day.  I haven't noticed any loss of weight or increased muscle tone, though the soreness I experience when I first got them has waned, as did the jelly leg feeling so I would assume that I am toning something and gaining more muscle control.
I have the tan version with white sole.  I treated them with silicone stain spray before wearing and after 9 days of camping they still look surprisingly new.  A little damp towel on the white parts and a nubuck brush on the uppers was all it took to freshen them up.