I ran with this shoe in college when I first got into running and must have bought five pairs before switching over the the "prettier"  Asics 2100 series.  Don't get me wrong, asics makes a good shoe, and it's definitely lighter, but after 4 years of using asics I starting to feel an aching in my legs and knees that only got worse over the years.  Doctors said that it was runners knee and that aside from not running and doing a series of knee strenghthening exercises, there wasn't much to be done.  After a while it got to the point where I was ready to give up running for good.  I was surfing the internet one day and saw these shoes for sale and decided to grab a pair since it was about time to get a new pair of shoes anyway.  After 1 month of running with these babies my knee pain is almost nonexistent and my legs actually feel stronger than they have in years.  If you're a clydesdale  (220lbs here) like me and have similar problems, try these shoes!!  I'll keep buying em as long as they sell them.