Keep in mind that Mizuno makes running shoes with specific footprints in mind - I tend to wear down the outer heel of my shoes which is why these shoes look like the outer heel is built up a little - this is meant to be and it makes my feet feel GREAT - much more comfortable.  Also bought 1/2 size larger since my feet tend to swell a bit when I run.  Please take your time and go to a GOOD professional running store to get fitted properly - your pro will watch you walk and run and also look at shoes that you've worn.  I went to the Annapolis Running Shop and they are GREAT.

I LOVE these running shoes - they feel like I have nothing on and are so comfortable.  Not bulky at all, I sometimes trip in shoes that are awkward but not these.  I would wear them every day all day if I could.  Next best thing to going barefoot.