I'm a 42G (give or take a little these days).  The band size is about right -- maybe a little snug, a 44 might fit but probably not a 46.  But the cups aren't really big enough for my breasts, which really isn't surprising because few bras do fit right unless they're labeled to be for that size range.

Also, I believe the directions say to hand-wash -- what nursing mom has time for that?  I'm washing it on delicate with the baby's clothes.