I use these shoes for walking, not running, 2-4 miles per day most days of the week at about 18 minutes/mile.  They fit my feet very well, and I no longer get blisters in the hot weather as I did from other shoes. They are comfortable, and I like the large toe box and support.  The twisted laces are great--they never have come loose.  The mesh top helps cool my feet.  Only negative I have found is that they do wear out--the interior padding on the ball of the foot goes first.  Whether this is worse than for other shoes, I don't know.  And they are a little heavy, likely  a consequence of their supportive structure.