My number 1 requirement in shoes while running is to not notice them at all while running.  My expectations are comfort, light weight, and support in all the right places and so far this shoe is hitting all of it.  I purchased a 10.5 EE and it fits well, fits even better if you invest in some high quality running socks which also add better support and breath-ability.  I run outdoors and the tread on these shoes have performed well in uneven and/or we surfaces.