I use the amazing Miura (lace-up) exclusively. I've had 5.10 before, and tried on 11 other pairs (Evolv, Scarpa, etc.) before settling on these. I was holding off due to the price, and ended up wasting an hour fooling with inferior designs and lower-quality materials when I should have just gone with these to begin with. I bought my first pair four years ago and haven't found anything better. I own two pairs now, and alternate depending on what I'm doing.

Pros
* Superb fit: the arch, heel and tongue shrinkwrap to my foot, and I essentially forget I'm wearing climbing shoes
* Sensitivity is fine. There's no searching for the jib or cleft
* Protection is great. I can point, hook and edge all day with no concerns
* Lacing system, though a bit odd at first, is fast, easy, and hasn't blown out an eyelet or lace path
* Laces seem to have some tougher material woven into them... they are tough and despite hundreds of lace-ups, they haven't frayed or snapped... they appear to be capable of enduring for the life of the shoe
* Edge rubber is firmer and the toe rubber is softer, like a bighorn sheep's hoof
* Lining holds up fine -- no pilling, tearing, moisture issues or general disintegration
* Rand is durable and despite a few wear spots, is holding up well with no blowouts or expanding holes
* Double heel loops to make fitting faster and reduce wear on a single loop. The loops are also offset so they don't rub the achilles' tendon
* Initial size is maintained throughout its life. I consider this a pro, while some might want some stretch. Just know that you're getting a lined shoe and it's going to stay true to size

Cons
* One of the most expensive climbing shoes... but ooh what you can do in it...
* The toebox is a bit big, even when my foot is at full downturn on a steep overhang. It doesn't bug me, but it does require exact sizing to minimize the bulk
* Smearing is.... OK. If you really like to toe-smear, look for something less downturned. These will probably change your style (I have seen this in my wear patterns across the two most recent pairs I own)
* When it gets wet, the heel can slip a bit, so I shake some foot powder in, before a session
* If you're a vegan, sorry... these are leather. Time to determine just how strong your resolve is... I did think about it, but given the feel of other shoes, compared to this perfect-for-me design, it was no contest

Other thoughts
My street shoe and hiking boot size is 10.5, which equates to a 44. I am most comfortable in a Miura 43, and can fit into 42.5 but they're tight enough to want to take them off during breaks. I feel that I can wear my 43s around for hours straight without feeling like I'll damage my toes, yet the shoes are perfectly ready to go, when i am. My 42.5s are reserved for use when the 43s go get resoled or are soaked, or I'm wanting optimum pointing and edging.

I can't wear La Sportiva's boots due to their characteristic narrowness, so I was surprised when these Miuras worked, and not just sort of worked, but more as if they were custom-made for me. I use these primarily on our indoor climbing wall, though I boulder on granite and sandstone in them as well. I can't make any recommendations for big-wall climbing in them, but given that Alex Honnold and Tommy Caldwell use them for that, well, I think that should fill in the blank.