I was fitted for the Asics 21-hundred series shoes years ago at a running shoe store and have been putting an average of 30 miles a week on them.  The start to feel a little "flat" after about 400 miles but I can usually push them to 600-700 miles.  I have a neutral stride and have not had any complaints with my 21-hundreds.  It is important to note though just because they work great for me doesn't mean they will be awesome for you.  I am a big advocate of going to your local running shoe store and having them fit you for the right shoe.  Unfortunately my local running shoe store went out of business which is why I buy from Amazon now.  The 2170's in Storm/Electric Violet have lived up to my expectations of the 2100's I have had in the past and are really cute!