Up to now, I had been using Nike running shoes.  I tried these on at a local sporting good store just to see how they fit.  They were quite a bit more comfortable than my Nike's.  I decided to try these out and ordered a size eleven from Amazon.
I have been using them for two weeks now for nothing but running.  They are excellent for me (I have wide and somewhat flat feet).  No break-in required, they felt comfortable running up to 5.5 miles right away.