I am a big believer in using shoes like these to make sure you run correctly, however because of a disc in my back that has degenerated to practically non-existent, I cannot take the impact of running anymore. I ordered these for walking barefoot while having protection from broken glass etc.
I went to the Vibram site and followed their sizing instructions, however my 2 outside toes will not fit into their little sleeves on the shoe, so I returned these and will go with a style that does not have the individual toe sleeves.

Shoes looked good and would definitely serve their intended function. I would suggest you go to a store to make sure you can fit into them before buying.