This is my first pair of Saucony running shoes and my first pair of more of a minimal shoe, although it is NOT a minimalist shoe.  I wear a 10 in NB and Ascics, so this shoe runs true to size for me.  I have a wide foot, which in Saucony is a medium.  When I first tried these on, I thought the toe box was a bit tight, but when running, the shoe is very comfortable.  You might find that you have a forefoot stike a little sooner than a "regular" shoe, due to the thinner sole.  There is plenty of comfort in that thinner sole. You might not get 500 miles out of them, but you'll run in comfort.