I never thought there was that much different in Men's scrubs fit, only features. However, if you are a man, you may notice that unisex scrub tops tend to have plunging necklines. Some women may like that, but most men would not like that at all. I certainly don't like that kind of look. These are cut with a more conservative neckline, and in addition, pleats in back, plus a hanging tab on the back yoke. Really appreciate that; plus these are cut large enough for a man's chest, and are not too short, like many unisex tops. ALSO: the material...higher quality, plus better stitching. VERY nice scrubs, with good pockets