I used to run in Asics shoes but my son (ultra runner) persuaded me to try the Brooks Glycerin 9.  Loved them.  Now I'm running in the Glycerin 10s.  The 10s have a shoelace that has a little bit of stretch to it which is really nice.  I used to feel like I was either tying my laces too tight or too loose.  These laces have just enough give to them to make them much more comfortable. I have a very high arch and tend to pronate slightly.  These shoes really stop that.  Running shoes are expensive and don't last nearly as long as we would like but I've found that I can get more mileage out of these shoes than any others.