I'm not a running shoe connoisseur; I wear them at work where I do a lot of standing and walking. I have worn the Cohesion 5 for a year now and was ready for a new pair. I like the colors of the Cohesion 6; I bought the dark grey with pink and citron detail. The colors are true to the picture. The shoe seems to run true to size (at least for the 10.5). As someone with high arches, I definitely notice a lack of arch support in this shoe; I will use an insert as I did with the Cohesion 5 model. There's something a little different from the earlier model in the heel: it is a little higher and ends narrower than on the Cohesion 5; they probably designed it that way for more "heel stability" or something, but I'm concerned that it will rub. Other than that, I like the Cohesion shoe because it doesn't push my foot in any weird way; it doesn't try to overcompensate for rolling inwards, for example. It's just a standard sneaker that breathes well, and that's precisely what I want.