I'm a bigger guy.  6' 2", about 235.  I've worn Orthotics for 21 years.  I will only buy Asics running shoes.  (I've also owned Adidas, Nike, New Balance, Reebok). My wife (girlfriend at the time) introduced me to Asics two years go. She noticed I have wide feet and wide tows. These Asics have a large tow box, and my tows don't feel cramped and uncomfortable. She also told me they are much more comfortable to run in. Boy was she right!  I have never ran in shoes more comfortable than these Asics.  I began using Asics two years ago. This is my third pair.  I have competed in triathlons and 5k races in these shoes.  I won't run in anything else!