Typically I wear size 11 shoe (Florsheim, Bostonian , New Balance) .  Shimano 45s fit , but were snug. These are probably a 1/2 size smaller than Shimano.  I have to gently tap my heel to avoid contact with the toe nails. ( my pair were ordered with no returns).  That's my bad.  The shoe itself is great value for the money. Light , firm and the black is not overly stylish.  You could probably order the 46s if you normally wear 11s.