I really cannot begin to express my appreciation for this Isotoner glove. My wife has RSD in her right arm and hand, a condition which causes considerable pain and swelling, and sometimes slow to heal. The gloves were recommended by our Physical Therapist who specializes in hand therapy. The swelling was dramatically reduced after wearing the glove only one night. This is an ongoing requirement for her and the swelling is nearly gone due to the therapy and the use of the glove. I have purchased a second pair of gloves, the next size down (Small) from the this pair. (Medium). It would be hlepful if these gloves were also available in left or right singles or a pair of right or left singles. I found the best buy on these gloves through Amazon.