I'm a nature photographer so I travel with multiple camera bodies and lenses, plus a laptop and won't risk checking any of them. This is surprisingly roomy. The zippered half kept my camera gear in place (wrapped in shirts for cushioning). The other half has straps which held my laptop securely and was easily accessed at the inspection point.  The small zippered compartment is perfect for little items; for me that meant cable, filters, etc.

The hard exterior protects everything.  The wheels and collapsable handle make transporting it a breeze.

This unit is roomy enough to handle all the clothing and such for a long weekend.

The only down side is not a serious one.  For extremely small commuter planes it must be checked plane-side.  That's when the rugged exterior is a real plus.