11/8/2014 EDIT:
After two solid years with these boots I've returned with an update. These boots have served me well in ALL conditions and  have worn-in perfectly.
The biggest gripe I've been dealing with is on down hill descents. The heel and heel box does not cushion as well as other boots. There is absolutely no shock support  when hiking down hill for long stretches. Without much success I've played around with various insole inserts over the years but I think the problem is the outer sole. It seems like the outer heel is stiff metal and not a springy rubber so I've usually ended my hikes with sore knees. I don't get blisters but I do feel sore in my knees after long hikes. Originally when I had this issue I assumed the boots needed a bit more break in time but after two years and hundreds of miles I had to take a star off from the original 5 star review for the lack of support and comfort.
These are great boots for ascents where rock and talus scrambling require sticky/sturdy toe rands but for long distance hiking over hard ground I did not find them ideal.

ORIGINAL REVIEW:

After 30+ miles on the Appalachian Trail these are my favorite boots of all time. I was worried about the blister situation and packed extra insoles just in case and found that the supplied peel away split insole that these come with either made the boots fit snug or too loose. So in the end I just used my old stillflex insoles (from an old Dolomite boot) and had no issues with blisters. I also use liner socks and pre-applied my own homemade anti-blister balm just to be safe and had no issues with blisters. The break in time for these boots took just the morning on the first day.
My favorite feature is that the rand and under-soles stick to everything. We were hiking late December and there were wet leaves, wet rocks and ice everywhere and I had no issues climbing over anything.
My one gripe is these are not the most cushioned boots I ever worn and downhills you tend to feel it more especially on worn down trails. But this can easily be fixed by inserting beefier cushioned insoles.
In closing I will sum up the awesomeness of these boots: In the last 10 years of hiking the first thing I always want to do when getting back to the car is throwing off my boots and getting into some dry cotton socks and sneakers or flip flops for the drive home. Last night was the first time in 10 years that I kept my boots on during the two plus hour drive back home. That is how comfortable these Salewa are!