I tried Mizuno shoes for the first time last year and the Wave Rider 15 quickly became my favorite running shoe.  Occasionally I would feel some aches along the bottom or tops of my feet with other shoes on my long runs, but no issues with the Mizuno shoes.  So it was a no-brainer to try the 16's.  I used them for a 7 mile run the first time out.  They are lightweight with moderate cushioning.  My feet are on the narrow side (high arch, neutral pronation) and the shoes fit me well.  I am normally an 8 in athletic shoes and wear a 9 in the Wave Riders.  The 16's seem to run slightly larger than the 15's, but it could be my imagination.  :-)