Pros:
Love the expandability and all the pockets.  Seems durable.

Cons:
I first noticed that the zipper on the main pocket was hard to zip over the top, even if there was nothing in it.  I thought the flap was maybe a teensy bit too tight, or too stiff... and that it would improve with use.
Then I noticed that the odd little velcro pouch that comes with it was sewn lazily and thus is too small (and lopsided) for anything to go in it.  Not sure what it was intended for... a tiny cellphone or walkie-talkie?
But I recently put the backpack to the test, on two small (week-long) trips.  Both involved carrying it through the airport; the latter involved carting my laptop around as I attended conference sessions.  And that's when I figured out - something is very wrong with this pack.  My back hurt quite a bit, but I thought I just hadn't gotten the straps adjusted right.  When I took it off, and turned it around so I was looking at the part that touches your back, where the straps are attached, I realized that they are sewn on crooked.  There is no way the pack can balance properly, or zip shut elegantly (see above).

I have to say, I'm disappointed in myself - that I didn't notice this right off the bat.  I'm usually more vigilant, especially when purchasing online.  But I'm even more disappointed in High Sierra, that they would let such a product pass inspection and be sold.  I would be wary of buying any of their products now...