I run usually between 20-40 miles a week and I alternate between the treadmill and outside on the pavement. These are by far the most comfortable shoes I have ever worn while running and most comfortable overall for casual purposes as well. I did some research first and discovered my foot type and found which shoe type would fit me best. These were recommended for neutral runners and runners that may underpronate. I went and tried them on and made up my mind in about 15 seconds to buy them. They are extremely comfortable, the biggest difference I notice is around/under the heel and on the balls of my feet and it is the closest feeling I will get to running on a pillow top mattress. They are that good. Highly recommended.