I don't know if I'd run in them.. however, I might give it a go at some point. Otherwise they really are quite comfortable. At the end of the day my knees and feet don't hurt, and that's really the main thing for me.

They're lightweight and cool, fit true to size, they've got a nice wide toe box so the toes aren't at all scrunched in a normal width shoe, the EVA insole is a bonus as well. It's too early to tell if they'll do anything for my supination, but even if they wear out in a few months, the cost is such that it would be easy to purchase another pair.