I have always been partial to NB running shoes.  Everyones foot is different, though, and for that reason everyone has different brand preferences.  For instance I can't fit into Asics at all, though most people find them to be very high quality.  That being said, I think these are the finest pair of running shoes I have owned.  I have never quite had a pair of sneakers fit this well.  I love the lateral support.  The vertical components of the "N" on the sides are actually straps that tighten with the top laces adding nice side support and adjustability to fit around the midfoot.  I usually get a 2E but with these I found the D to be perfect for that reason.  The material quality seems top notch.  I tried on a few of the lower number models before getting to the 850's and found the fit and materials sadly lacking.  I am so impressed with these that I am considering buying another pair to have on hand.  Strongly recommend to NB fans who have found them to be a good fit in the past.