For the last 8 or so years, I've ran in Brooks Adrenaline GTS shoes and have never once wanted to try another pair.  I don't believe there is a shoe out there that can be called "the best."  It all depends on your feet and how the shoe fits.  Sometimes I buy 2 pair when I find good deals online.

I'm a bigger runner too- well, heavier that is.  205-10 lbs, 5'11" frame and I run about 6-7 mi 5x/wk.  I replace them about every 400-500 miles.

Great shoe and you can get awesome deals online if you get the previous models (GTS9, 8s).  They're just as good as the newer ones!