I've been using this product for about two weeks now.  I have to say that overall I'm very pleased with it.  For the moms who pump exlcusively, you all know it's hard to find the time to do everything that needs to be done and a lot of times, the first thing to get axed off the list is pumping.  But now finally, I can pump consistently throughout the day, and not have to stop because the baby needs to be fed or I need to eat! I have a backpack Medela InStyle pump, so if I need to move around, I hook up the battery pack to the pump and put the backpack on and away I go.  It's kind of awkward at first, but you get used to it.

PROS:
-The adjustable panels and zipper panel are great.  I get a good seal on the breast shields and have had no leakage.
-I ordered the L/XL/XXL, am a 40DDD in my regular bra and it's so adjustable I could be much smaller or much larger and still be able to use this.
-Soft, comfy fabric that's also very sturdy and will last a long time
-Easy to use with the shields, easy to put in and take out

CONS:
-Because it's a completely flat fabric, no cup at all, it can take a little adjusting to get it comfortable.  If you are one of the fortunate ones whose girls are still where they were when you were 18, then it will be more comfy. :) If not, since there is no cup or support, it can take a little getting used to.
-To get the good seal, it has to be a snug fit.  The compression hinders my milk flow just a tiny bit.  Towards the end of the pumping session, I always take the bra off and massage to make sure and get everything out.

I couldn't find many reviews of large-breasted women who have used this, so I had to take a chance, and I'm very happy with it.  Another bonus, my milk has increased since I started using this!