I've been running in Asics Kayanos it's been 15 years.
Kayano 17 got a lot lighter (each shoe is 12.3 ounces) and has more cushioning in the forefoot.
Off-center laces are designed to conform to the bony structure of the foot and therefore reduce irritation.
Mine are black and I really love the way they look (I am not one for pink running shoes.)
All in all, increased comfort and a better fit, but still feel like the Kayanos you've grown to love.