I am a woman that needs a women's size 11 1/2 shoe, but most don't make them, so in order to get my size I have to try to find a men's narrow or B width in a 9 1/2.  New Balance does that.  As far as sizing, these are perfect. As far as comfort, thats another story.  If I pay this much for a shoe I expect enough support where I don't need to add $30 more for orthotic inserts.  Here the shoe fails.  For a running shoe, I expected better, for the price I expected much better.  I wish I would have ordered the 845 or 846 instead, or a cheaper shoe and bought the inserts. Everyone is different, for me it just doesn't work.