I have had this since May 2010 and it's held up well; I use it back and forth between work each day.  The nylon covering near the lower attachment point on the right side came away from the seam by the zipper; however, this was a non-load-bearing seam and I think it just wasn't properly edged.  I haven't really seen any wear on the load-bearing points that concerns me.

I like that I have the ability to change the strap from one side to the other, which came in handy when I had a sore right shoulder.

My decision to buy this bag was based on the sling bag style, not really for the laptop compartment alone.  Even still, I can't fit my 15" MacBook Pro (late 2008) into the padded section within the main compartment, which is intended to protect a laptop.  I can barely get it past the zipper (which I wish was a multi-directional zipper, not just from the bottom up).  With some finessing I can get it in there if I put the laptop in the main compartment proper, but it's a challenge getting it past the zipper, and means I can't really put anything else in the main section with it.  If you're buying it to carry a laptop whose length is greater than 12 inches (mine measures 14 inches), or is greater than 10 inches in width (I just measured the width of the padded section), you may wish to reconsider.

[edit] I'm still using this bag as of May of 2013. It's holding up well, and haven't found a bag I like better for day-to-day use. I just don't put my laptop in it often, and am extra careful when I do have to tote it.