I am one of those people who cannot wear an underwire; not an easy thing in this size-range.  Years of trying to find any kind of comfort in a wire left me cutting them out of anything I bought.  A professional boutique bra-fitting finally told me what I needed to know.  The shape of my body/ribcage would always make an underwire a painful thing.  This is the best and most-comfortable large-sized (40I) wireless bra that I have been able to find.  That said, it still does have a drawback.  I am NOT a fan of the straps.  They have a little metal clasp in the front rather than the traditional type of straps.  I have found that over the course of the day, the metal clasp moves ever so slightly and they are nearly impossible to adjust on-the-go.  I would prefer normal straps.  Another thing I noticed is that if you were wearing the old version of this bra (stlye GD0110), you will now need to order 1 bandsize lower and 1 cupsize higher (I was 42H, now 40I).  I saw that helpful tip on another sight before I ordered and they were completely correct.  Still, I much prefer this to the old GD0110 which is now discontinued.  The Jayne is much more stylish, comfortable and the amount of material sitting against your ribcage is what it should be.  I always found the GD0110 to have just too much material at the ribcage and a very outdated look which made this 30-something woman feel like she was pushing 80.  I only wish that bra manufacturers would realize that big-busted girls would like to have more options too... How about some nice colors beside nude & black?  How about seamless/padded cups that conceal under a knit shirt?  Why are these only available to people who could go without a bra if they wanted to ;)  Long story short; it's not perfect but it is the closest I've found so far.  Give it a try!!