I am currently rotating between two pairs of these for 35-mile weeks, and have retired a third pair at the end of its life.  Last weekend I ran a 1:50:09 half marathon in a pair of these with ~170 miles on them.

I bought my first pair of these in December 2009 to replace a pair of Saucony Triumphs; I was running about 15 miles per week and was a little over 200 lbs (I'm 6'1"); I intended to really step up the running for 2010 and chose the Omni 8 for the job.  They have held up remarkably well as I've increased both speed and mileage over the last year.

They are great for me - excellent support, good stability in what's still a fairly light shoe.  In my first pair, the support was practically as good as new until about 550 miles, which is a *long* life, especially since I was kind of on the heavy side at the outset.  I pushed them too long, and in the last 50 miles I noticed them really breaking down; but they held together much better than I expected.  My other pairs are at 170 and 70 miles; I find they take a good 50 miles to break in.

I do plan to add another, different shoe into my rotation for speed work and for variety, but these shoes are certainly some great all-around running shoes.