Well I bought these because I have run many miles on my Asics and they were feeling like a rougher ride as time went on.  I ran on the tread mill for the first time on the Mizuno Wave creation 12 shoes and my experience was OK, but not better then the worn Asics.  I knew the shoe would loosen up, so I tied them tight to start and yes they did loosen up...one almost too much.  The footing felt very flat to me.  I'm use to a forward leaning shoe which pads the heel and moves you forward.  At times when running rather then a heel to toe, the step was heal toe at the same time.  After warm up they for the most part got comfortable, but they are not going to change my life.  I'm not going to give up on them though and have to make adjustments to my stride and see out it goes on the road.  My advice is if you can get someone to try them on and run 5 miles in them.  If they work for you then buy them.