This is my second pair of MBTs and they are pretty comfortable.  My first ones are sandles with open toes and I wanted something with closed toes so I could wear with more things.  My other MBTs were comfortable from day one but these took a little time to break in.  If I wear them all day, my feet do get blistered.  The top part seems to rub on my foot, the area above the big toe, and irritate my skin.  My feet also hurt the first few times I wore these on the bottom part.  I'm not sure if it is due to the holes in the cushioning or what.  The insert does come out but it leaves it without cushioning.  I guess this is if you wanted to put in your own insoles / padding.  I tried it with some Dr. Scholl's but it didn't work too well.  I'm going to get some better ones and try it again.  I would recommend getting this shoe in a half size bigger because after a while they might start feeling too tight.  I normally wear a 7 (also in my other MBTs) but I had to get a 7.5 in these.
Overall I would get this shoe again because I do like the way they look and they are great for walking around but they do take a little time to break in.  If these didn't require any breaking in time and leave my feet with blisters, they would get a 5 star rating.