My Mom used the set on her first plane trip in 30 yrs. She loves them. She has 20 med bottles PLUS insulin and needles. Her kindle fire, her shampoo and conditioners and a few other things fit in the sm bag. A pair of hiking boots and sneakers and clothing for a week fit in carry on.  She has no problems with her bags.. I wish her flight could have been the same. BUY THE BAGS! The price is the best!