I slightly overpronate and am 5'7" and 170 lbs, run 3.5 miles 3 time a week. Previously had Asics Nimbus. These are similar to the Nimbus in ride but much better isolated from shock. I used to be a little sore after my runs, now I feel great. I have a 4E WIDTH foot and got the 4E but they are a little narrow-more like 2E. I put a 5# weight in to stretch the shoe out overnight and now can run without pain. However, if your feet run wide I would get a wider size than you think you need.