I have had these shoes now for about a month.  I have put 15+ miles on them (not a big runner).  I was told about these by friends who are avid runners and old like me (40's).  My friends told me that my knee, back and ankle pain would go away after using these shoes and I thought they were crazy....but they weren't.  It takes a bit to get used to them, but even at 6'3" and 235, these shoes make a huge difference.  My time isn't up to what it was in regular shoes, but I feel the difference when I am done.  Just remember to warm up and understand that YOUR CALVES WILL FEEL THE CHANGE IN RUNNING STYLES from regular shoes!

I would definitely recommend these shoes to friends.