For some reason, Clarks does not make size 10.5 for women. I wear a 10 or 10.5, depends on the shoe. I have another pair of Clarks Unstructured in a 10 -- got a C/D (thanks Clarks for offering wide widths) -- and those shoes are plenty generous in the toe area. This particular style (Un. Loop) in a 10 M was too small, and I returned them. Thus, I can't comment on the comfort or durability of this style.