I can't believe it, but the 4E is a regular wide shoe. I ordered my first pair as the regular size. I could not get the shoes on. So I returned them to Amazon.com. I really liked these shoes and the price after shopping around. So I ordered a second pair as a 4E and they fit perfectly. As a big guy, I have been able to walk 12 miles a week in these shoes. Yesterday, I did a 5K under 45 mins non-stop in these shoes, plus other exercise. Wonderful shoe, but you need a 4E, if you do not have a skinny foot!