We did carry-ons to Europe on a trip to visit several cities in 14 days.  We loved these envelopes, easy to pull out of the suitcase when looking for other items, keeps things folded and tidy.  Tip- use the hard plastic folding guide card as a "shelf" in the center of the packed envelope, makes it easier to find something without accidentally unfolding other items.  On motorcycle trips, we love the Eagle Creek compression bags, but they aren't good for non-knits because of the wrinkle factor - the envelopes kept the clothes in better condition for least amount of touch-up. Tip - take along a small empty spray bottle. Spritz your tops and bottoms the night before you wear them and hang up - this gets out any small packing wrinkles - I hate ironing!!  On this trip, we used the compression bag for the dirty clothes, so they take up the least amount of space (don't put your underwire bras in these). We also used the Eagle Creek cubes for packing smaller items, underwear, socks, other small knits, etc.