Like others I had a problem with the seam on the heel.  My second time out in them I went for a 5 mile run and by the end I had a nasty, bloody blister on my left Achilles tendon.  My solution was to get a C-Clamp and tighten it as hard as I could on the offending spot overnight.  The next day I took it off and the place was flat.  I've been on two long runs since and have had no trouble with rubbing there.  Otherwise I love these shoes!  They've got just enough padding so that I can run on the street or on cinders and be fine the next day, but they're really light and allow my pronating feet to function naturally.

Update:  After a few days the seam popped back up so I had to keep mashing it down.  Finally I got tired of doing this and cut out the seam at the heel.  I now use these shoes only for weight lifting in my basement.  If I could do it over I wouldn't buy them.