I've been a long time fan of Brooks Glycerin, but after a trip to my local running store to get fitted the Asics GT 2150's were recommended to me. I had previously ordered a pair of Saucony pro grid from running warehouse but they brought on extreme pain due to their mid-high arches. I have a moderate to low arch, and found that the GT 2150 is a great fit. With these shoes I no longer feel pain in my arches and thereby have a comfortable long run. It's very supportive and my primary shoe for anything over 5 miles because of it's structure and protection. For my shorter/faster runs, I prefer my Brooks Glycerin because of it's lightness (although it's a neutral shoe). This is a great product, I'll be sure to buy more pairs to replace old ones.