I, too, purchased this bag due to the enormous books I have to carry for nursing school.  I did a lot of research before choosing this bag, and while I'm not dissatisfied with it, there are a lot of things I'm not thrilled about.

The Good:  the bag meets my needs size wise, with enough room to carry: a large binder, two normal sized text books, 15" laptop, planner and numerous smaller supplies.  The wheels seem to be well designed, and I've never had an issue with the handle.  Backpack rolls smoothly and the handle on the top is super handy when you encounter a set of stairs.  The numerous pockets with organizers are nice, and really help you find something in a hurry.

The Bad:  the zippers are definitely not top quality.  My bag came with one broken zipper, and with the way the others zip, I'm not sure they'll all last through the school year.  While the bag is large, once you put a laptop in it, you are severely limited on what you can put in the largest compartment.  The laptop pouch seems to be so well cushioned, that it takes up 1/3 of the overall space.  Lastly, what bag maker these days doesn't put in mesh pouches for water bottles?  There are zippered pockets on the side that you can shove a water bottle in, but they aren't nearly big enough, nor designed properly for that.

The only other comment I have, is be incredibly careful as to what you put in the largest compartment.  Today, while pulling out on of my larger textbooks, I realized that the little wheel wells in the large compartment completely dented my textbook binding.  Because it's a textbook I need for the entire year, I'm not super thrilled about it.  I will live with it, but I may be looking to get a higher quality backpack come next year.