Bought two pairs of these in different colors for work and wanted them to at least match what I'm wearing. So no, I don't use them for running. However, I do quite a bit of walking and standing in them. For my use, they are quite lightweight and comfortable and having the mesh material helps because of the ventilation it provides. Apparently no local vendor in my area has carried this brand for awhile so that's a plus in my book.
I gave these a 4 star rating because I have a pair of SyncroFloat III's and loved them - these feel a bit more snug in comparison despite being listed as the same size (other reviewers may have noted this as well) but not enough to make me feel uncomfortable. These also don't have quite the same "quality" feel as the older pairs of Pearl Izumi shoes I own, but that seems to be the case with a lot of things these days.