I do love the Pearl Izumi brand and my last pair of spin shoes were indoor and not outdoor road; there is a difference.  I also run in Pearls and feel they make a great shoe.  I am a female with a wide foot so I'm used to purchasing men's athletic shoes. These specific spin shoes are extremely stiff and unforgiving. They are probably sized right but you definately need to purchase a whole size bigger because of your feet swelling during use and your toes hitting the front of the toe box and the shoe not giving at all.

NOTE: I did end up selling these spin shoes to a girl in my spin class that wears a 7 1/2.  She said they fit her great. I purchased a size 9 1/2.  So 2 full sizes is an issue when ordering athletic shoes.