I have flat feet and my knee was hurting for a few months while running.  My runs would usually end in pain after 2-3 miles.  I had no idea it was my 7 month old shoes until I put this pair on.  I had no more pain and could resume my usual 5-10 mile runs.  I guess they offer the proper support in the right part of my foot.  They're that good!  I'm not too crazy how they look but running without pain is more important to me.