First, color:  I wanted something not too flashy that would be acceptable for street wear, so tried the grey/red (really orange).  Good choice - they are darker and more subdued than they appear on my screen; the grey-blue mesh is particularly more grey than blue.  Also the light-colored sole layer is light grey, not at all white, as it appears.
Second, size:  my previous Altras were the Lone Peak 2.0 in size 8D (Wide, I assume): even though I usually wear 6.5 Wide in street shoes, I needed that much extra sizing to get enough room for my toes particularly in depth of the toe box.  They always seemed a bit big, so I tried a 7.5 this time - way too big, dropped down to 7.0, and kept those but after wearing for a couple months, it seems likely I could have worn 6.5.  The 7's are plenty long, fairly wide (though not marked D or Wide), plenty of depth in the toe box, and plenty of coverage over the instep (unlike the 2.0's which barely closed over my somewhat high instep.)
Comfort level is still very good.  I wanted the waterproof Neo for a trip to Ireland, but we hardly had rain, so don't know how it performs yet.