I run multiple times a week about 4 miles. I am 50 years old and weigh over 200lbs.  I have some minor issues with joint, foot, and knee pain especially when I don't run in the right kind of shoe.  I had been buying ASICS Gel Nimbus for years but they changed the latest model up and it was terrible. They were stiff and I felt every foot strike like I was wearing a brick.  I needed a well cushioned shoe that was reasonably lightweight with good rebound so you don't lose all your energy in the cushion. These shoes are PERFECT for that.  They are better cushioned than the Nimbus was even with the models I loved. They give more rebound as well and my mile times have gone down which is nice as well as not feeling as drained to achieve higher rates of speed. There was no real break in period required. They were instantly comfortable and remain so. Contrary to some concerns, the toe box was just fine after coming to it from the ASICS. I love running in these shoes. I highly recommend them for anyone who needs more cushion for walking and running.