That in itself is justification for the enormous project that the Institute of Health Metrics and Evaluation (IHME) in Seattle has led over the past five years, involving nearly 500 researchers, to assess the global burden of disease.

This last statistic provides justification for the enormous project that the Institute of Health Metrics and Evaluation (IHME) in Seattle has led over the past five years, involving nearly 500 researchers, to assess the global effects of disease.
