In first-generation hybrids, gray wolves are most often crossed with wolf-like dogs (such as German Shepherds, Siberian Huskies, and Alaskan Malamutes) for an appearance most appealing to owners desiring an exotic pet.ntra-hybridization between dogs and other subspecies of gray wolves are the most common wolfdogs since dogs and gray wolves are considered the same species hence are genetically very close and have shared vast portions of their ranges for millennia.