How to make powerpoint slides advance automatically. Launch PowerPoint. Open the previously prepared presentation file. Click on the Transitions tab and select the first slide. Find the Advance Slide section and uncheck the On mouse click checkbox.Put a tic in the After checkbox and set the time in the input box. If all files are to be advanced in equal periods of time click the Apply for all slides tool button.ow to make powerpoint slides advance automatically. Launch PowerPoint. Open the previously prepared presentation file. Click on the Transitions tab and select the first slide. Find the Advance Slide section and uncheck the On mouse click checkbox.