Drastic Measures. An unusual amount of urine or unusually moist conditions in the subfloor can make odor remediation difficult, and in some cases, the only solution is to remove the affected part of the subfloor and replace it.rastic Measures. An unusual amount of urine or unusually moist conditions in the subfloor can make odor remediation difficult, and in some cases, the only solution is to remove the affected part of the subfloor and replace it.