Having identified meth's effects on cells, Piomelli and his co-researchers decided to figure out a possible way to prevent the drug's effects on the body. If we can stop nuclear factor kappa beta, they reasoned, by increasing the body's natural inhibitors of that protein, then we can limit the production of ceramide.eth, scientists from the Italian Institute of Technology and UC Irvine say, causes abnormalities in the fat metabolism of cells and this triggers a rise in a type of molecule which promotes cell death. Understanding this, they say they can prevent the drugâs radical effects.