Clindamycin phosphate topical gel, 1% is a topical antibiotic approved for the treatment of acne vulgaris.This drug belongs to the class of antibiotics known as lincosamides.or non-inflammatory lesions, the mean percent reduction was 25% for clindamycin phosphate gel and 12% for the vehicle gel. The total mean percent reduction in lesion counts at the end of treatment was 38% for clindamycin phosphate gel and 27% for the vehicle gel.