Lung regeneration is usually very minimal. If you lungs are so badly damaged that they can no longer transfer adequate amounts of oxygen into your body, you may need to consider a lung transplant if no other treatment options have been effective.However, some lung regeneration does occur after you quit smoking.ilia are tiny cells that assist with clearing mucous from the airways and help you to breathe properly. Lung regeneration after smoking usually occurs from one month after quitting until about nine months after quitting.