{{model.addEditText}} Print. 1  Prep. 5 m. 2  Cook. 30 m. 3  Ready In. 35 4  m. Preheat the oven to 375 degrees F (190 degrees F). Grease a 9x13 inch baking dish.  Place the tilapia fillets in the bottom of the baking dish and dot with butter. Season with Old Bay seasoning and garlic salt.