Still, itâs hugely convenient. And although youâll sometimes hear that midtown has high crime rates, most of that is petty crime, like pickpocketing, directed at tourists; violent-crime rates are very low. 40th St. to 59th St., East River to Fifth Ave. 7 to Grand Central | 4,5,6 to Grand Central | 7 to Fifth Ave. | E,V to Fifth Ave.-53rd.