Apply a thin film of Clindamycin Phosphate Topical Solution or use a Clindamycin Phosphate Topical Solution pledget (pad) twice daily to affected area. More than one pledget may be used if needed. Discard any used pledgets and wash hands thoroughly after application.ell your doctor all prescription and over-the-counter medications you are taking. Clindamycin Phosphate Topical Solution should be used during pregnancy only if prescribed. It is not known if the topical form of this medication passes in breast milk. Oral forms of clindamycin pass into breast milk.