Small tests can end up being more expensive than WES â¢ Ordered test: CMT Sequencing Test, Lab XXX â¢ 23 genes including CNV analysis â¢ Clin. Sens. = 65% â¢ Enhanced Exome (would need additional PMP22 del/dup) â¢ 34 genes (99.5% bases >20x) â¢ Clin. Sens. = 75-80% â¢ Exome turned out to be cheaper (enough to add PMP22del/dup) E X A M P L E