Squamous cell carcinoma (SCC) is the second most common type of skin cancer. It also commonly arises on areas that are chronically exposed to the sun, such as the face, scalp, neck, upper back, and arms.quamous cell carcinoma can occasionally spread into the lymph nodes and internal organs. This occurs more often with large, aggressive squamous cell carcinomas or rapidly-growing tumors on the ears, scalp, lips or genitalia.