Wiring can cause door lock problems, but switches and actuators are more common. DennisB DenLorsTools.com Â© Summary: A quick common sense way of thinking about and pinpointing the most common door lock problems on many vehicles. There are several things that can cause the power door locks not to work properly. The most common cause of a single door lock not to work, is a bad door lock actuator (also called a door lock solenoid or door lock motor). Another common problem or cause of door locks not working is simply a bad door lock switch.