Some of the Physical Effects of Meth Use. Some of the most common effects of meth use appear on an addictâs face. For example, even one use of meth can cause your face to dry out and get extremely itchy (it is being suffused with toxic chemicals, after all).ome of the most common effects of meth use appear on an addictâs face. For example, even one use of meth can cause your face to dry out and get extremely itchy (it is being suffused with toxic chemicals, after all).