(June 2011). Infarction is tissue death (necrosis) caused by a local lack of oxygen, due to an obstruction of the tissue's blood supply. The resulting lesion is referred to as an infarct (from the Latin infarctus, stuffed into). Myocardial infarction is the partial death of heart tissue commonly known as heart attack.June 2011). Infarction is tissue death (necrosis) caused by a local lack of oxygen, due to an obstruction of the tissue's blood supply. The resulting lesion is referred to as an infarct (from the Latin infarctus, stuffed into). Myocardial infarction is the partial death of heart tissue commonly known as heart attack.