Messina Earthquake. On December 28, 1908, at approximately 5:20am, Europe's most powerful earthquake shook southern Italy. Centered in the Messina Strait, which separates Sicily from Calabria, the quake's magnitude equaled a 7.5 by today's Richter scale.n December 28, 1908, at approximately 5:20am, Europe's most powerful earthquake shook southern Italy. Centered in the Messina Strait, which separates Sicily from Calabria, the quake's magnitude equaled a 7.5 by today's Richter scale.