The House Rabbit Life Expectancy. Taken from the books 'The Essential Rabbit' & 'The Rabbit Handbook'. Different rabbit breeds have different life expectancies, and of course, any number is just an average. Rabbits should be expected to live at least 5 years; they can live as long as 15 years. Medium and large sized rabbits tend to live longer than dwarf rabbits. Breeding rabbits can easily produce litters until they are three to four years old.