Freebase(0.00 / 0 votes)Rate this definition: Nue. A nue is a legendary creature found in Japanese folklore. It is described as having the head of a monkey, the body of a raccoon dog, the legs of a tiger, and a snake as a tail. According to the legend, a nue can metamorphose into a black cloud and fly. Due to its appearance, it is sometimes referred to as a Japanese chimera. Nue are supposed to be bringers of misfortune and illness.