Women who get radiation therapy after lumpectomy have a 50 percent lower risk of breast cancer recurrence and a 20 percent lower risk of breast cancer death compared to women who get lumpectomy alone [ 4 ].Overall survival with lumpectomy plus radiation therapy is the same as with mastectomy [ 5 ].umpectomy plus radiation therapy is an option for most women who have early breast cancer or ductal carcinoma in situ (non-invasive breast cancer). In some cases, it is also an option for women with locally advanced breast cancer.