Vaniqa Prices. This Vaniqa price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies. The cost for Vaniqa topical cream 13.9% is around $167 for a supply of 45 grams, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. Vaniqa is available as a brand name drug only, a generic version is not yet available.