Take the ferry to Margarita Island if you already are in Venezuela. The principal ferry departure points for Margarita Island are Puerta la Cruz and Cumana, both of which are several hours east of Caracas on the northern coast of Venezuela.ake the ferry to Margarita Island if you already are in Venezuela. The principal ferry departure points for Margarita Island are Puerta la Cruz and Cumana, both of which are several hours east of Caracas on the northern coast of Venezuela.