The core symptom of depersonalization-derealization disorder is the subjective experience of unreality in one's sense of self, or detachment from one's surroundings.ymptoms can be classified as either depersonalization or derealization. Depersonalization is described as feeling disconnected or estranged from one's body, thoughts, or emotions. Individuals experiencing depersonalization may report feeling as if they are in a dream or are watching themselves in a movie.