Using Creams and Medical Treatment. 1  1. Apply medical cream that contains .075% capsaicin. 2  2. Use salicylic acid cream or gel. 3  3. Spread over-the-counter corticosteroid cream on the plaque for fast, short-term relief.  4. Try vitamin D 1  ointment. 5. Apply anthralin to the plaque.  6. Use tazarotene (tazorac) gel at night.