Betamethasone cream is a medicine used to treat skin infections. Typical skin infections treated by creams containing this medication include athlete's foot, jock itch, and ringworm.ome individuals may experience hives as part of an allergic reaction to betamethasone cream. Bruising is one side effect of betamethasone cream. Betamethasone cream is used to treat skin infections. Betamethasone cream can be used to treat ringworm.