Question: is this a 2) strong advice, 1) weak advice 0) no advice?

Statistical Power and False Discovery Even after enrichment by selection of an appropriate discovery cohort, and testing only for rare GSVs with dominant phenotypic effects, low statistical power remains an important issue, with increased rates of false negative and false positive associations at a given significance threshold and inflated estimates of effect size (“winner’s curse”) [20], [31], [32]. 
user
This is no advice
assistant