Question: is this a 2) strong advice, 1) weak advice 0) no advice?

S246L also shifts the availability curve to the left (Fig. 5A), but this -7 mV shift alone is clinically silent (unaffected mother and sister), compared with the -10 mV shift purported to cause HypoPP for the R672G/H mutations (28). 
user
This is no advice
assistant