Question: is this a 2) strong advice, 1) weak advice 0) no advice?

While NP has traditionally been considered less responsive to opioid therapy (Caraceni et al., 2004; Gilron, Watson, Cahill, & Moulin, 2006), controlled clinical trials and clinical experience suggest that a subpopulation of patients with NP may benefit from treatment with opioid analgesics (Benedetti et al., 1998; Eisenberg, McNicol, & Carr, 2005; Rowbotham et al., 2003). 
user
This is no advice
assistant