Question: is this a 2) strong advice, 1) weak advice 0) no advice?

A number of gene polymorphisms involved in development of knee osteoarthritis have been identified, such as those localized in or adjacent to the encoding sequences for the vitamin D receptor [14,15], estrogen receptor alpha [19], calcitonin [20], interleukin-6 [21], SMAD3 [7], and matrix metalloproteinase-1 [22]. 
user
This is no advice
assistant