Question: is this a 2) strong advice, 1) weak advice 0) no advice?

The finding that treatment with demethylating agents is able to completely revert the binding of MeCP2 to the BIM locus (Figure 5F) suggests that BIM silencing could occur through the following steps: CpG methylation→binding of MeCP2 to methylated CpGs→recruitment of SIN3 core-pressor complex→deacetylation of histone tails→chromatin condensation (Figure 7). 
user
This is no advice
assistant