Question: is this a 2) strong advice, 1) weak advice 0) no advice?

Numerous biologic therapies have also been evaluated for refractory (most often defined as progressive disease unresponsive to conventional therapy, such as glucocorticoids and cyclophosphamide) and persistent disease.6 While cohort studies outline the use of deoxyspergualin, anti-thymocyte globulin, and TNF-alpha antagnosists, there is a greater level of evidence supporting the use of intravenous immunoglobulin and RTX for refractory and persistent disease1,30–34. 
user
This is no advice
assistant