Question: is this a 2) strong advice, 1) weak advice 0) no advice?

Accordingly, genetic analysis of heritable quantitative endophenotypes such as cognitive function that are often considered as intermediates in the causal chain leading from risk allele to clinical disease may help to uncover loci that increase or reduce susceptibility to dementia in its preclinical phase [Bennett et al  2009; Carmelli et al  2002; Gottesman and Gould 2003; McClearn et al  1997; Shulman et al  2010; Swan et al  1990]. 
user
This is no advice
assistant