Question: is this a 2) strong advice, 1) weak advice 0) no advice?

There are several possible reasons for the apparent difference between children and adults: it may reflect population differences (the child carriers of the GSV were from France and the UK, the adults primarily from Nordic countries); it may reflect cohort ascertainment, for instance that the child cohorts did not include overweight or mildly obese subjects – it is notable, however, that the deletion was not reported at a comparable frequency in cohorts of children with common obesity [16]; it may reflect a genuine attenuation of the effect of the deletion in adults, so that impact of the GSV on obesity becomes less pronounced with increasing age; or the severe obesity observed in children may have been triggered by an aspect of the modern obesogenic environment that was experienced to a lesser degree by older subjects. 
user
This is no advice
assistant