Question: is this a 2) strong advice, 1) weak advice 0) no advice?

In addition, Hansen et al showed that a high dose of remifentanil (0.4 μg/kg/min) added to combined general and epidural anaesthesia could induce OIH and/or acute opioid tolerance after major abdominal surgery at the immediate postoperative period (0–2 h)19. 
user
This is no advice
assistant