Question: is this a 2) strong advice, 1) weak advice 0) no advice?

Since total cortisol concentrations under the intravenous cortisol clamps were comparable in the men and women, and calculated free cortisol levels were actually lower in women, a straightforward hypothesis is that E2 may mediate enhanced (free) cortisol feedback on ACTH secretion in women. 
user
This is no advice
assistant