Question: is this a 2) strong advice, 1) weak advice 0) no advice?

Over the preceding decade, randomized controlled trials have standardized approaches to induction of remission and maintenance therapy.6 However, despite continuing improvement in patient outcomes with generalized disease, treatment of early systemic disease, and particularly granulomatous inflammation, confined to the respiratory and ENT tracts is not supported by the same evidence base to guide clinical practice.22 Disease relapse also remains common and PR3-ANCA antibody positivity, most often associated with GPA, and cardiac involvement are recognized as independent risk factors for relapse. 
user
This is no advice
assistant