Question: is this a 2) strong advice, 1) weak advice 0) no advice?

The effect of grade 3/4 elevations in alanine aminotransferase (ALT) or aspartate aminotransferase (AST) during the first two cycles and at any time during trabectedin treatment on progression-free survival (PFS) and overall survival (OS) were analyzed. 
user
This is no advice
assistant