Question: is this a 2) strong advice, 1) weak advice 0) no advice?

Only BIN1 (rs744373) and CR1 (rs3818361) out of the 8 non-APOE genetic polymorphisms examined were associated with rate of change over more than 10 years in global cognition and verbal fluency, respectively, in a study of 4,931 participants in the 3-C Dijon study (median age 74.0 years), and none were associated with decline in processing speed, visual memory, or premorbid mental abilities [Vivot et al  2015]. 
user
This is no advice
assistant