Question: is this a 2) strong advice, 1) weak advice 0) no advice?

Our findings also have therapeutic implications: After the defect in Nav1.4 was established in the patient, therapy with pyridostigmine (60–120 mg three times daily), which increases the number of AChRs activated by each quantum, improved the patient's endurance; additional therapy with acetazolamide (250 mg twice daily), which is known to mitigate periodic paralysis due to Nav1.4 mutations, prevented further attacks of respiratory and bulbar weakness. 
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This is no advice
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