Question: is this a 2) strong advice, 1) weak advice 0) no advice?

A subsequent sampling of two patients resulted in the detection of two ST410 isolates in both samples, the first patient with 11 SNP differences between the genomes of isolates collected 13 months apart and the second patient with three SNP differences between the genomes of isolates collected 5 months apart. 
user
This is no advice
assistant