Question: is this a 2) strong advice, 1) weak advice 0) no advice?

Plasma concentrations of clusterin have been reported to be associated with atrophy of the entorhinal cortex and more rapid global cognitive decline in AD patients [Thambisetty et al  2010], and were also negatively correlated with global cognitive function and with attention-processing speed as measured by the DSST in 664 participants in the Sydney Memory and Aging Study (mean age 78 years) [Song et al  2012]. 
user
This is no advice
assistant