For example, you can use the verb "go" and the prepositions "to" and "from" in a literal, spatial sense. "The messenger went from Paris to Istanbul." You can also say, "Biff went from sick to well." He needn't go anywhere. He could have been in bed the whole time, but it's as if his health is a point in state space that you conceptualize as moving.
Por ejemplo, puedes usar el verbo "ir" y las preposiciones "a" y "de" en un sentido espacial literal: "El mensajero fue de París a Estambul".