The two drugs actually caused problems. They increased glucose. They could throw somebody into diabetes who would otherwise not be in diabetes, and so you would want to use the two drugs very carefully together, perhaps not together, make different choices when you're prescribing.
Los dos fármacos causaban realmente problemas. aumentaban la glucosa. Podían llevar a alguien a la diabetes que de otra manera no tendría diabetes, y por eso uno debe usar ambos medicamentos juntos con mucho cuidado, o tal vez no juntos, o puede tomar decisiones diferentes al recetar.