Non-cytotoxic peptide with immunosuppressive and insulinotropic effects. Induces an increased production of the anti-inflammatory cytokine IL-10 and inhibits production of the pro-inflammatory cytokines TNF-alpha and IL-1beta, when incubated with mouse peritoneal cells. Does not display growth-inhibitory activity against the Gram-positive S.epidermidis and Gram-negative E.coli bacteria and against the opportunistic yeast pathogen C.parapsilosis (MIC>128 uM). In addition, it lacks cytotoxic activity against mouse erythrocytes (LC(50)>500 uM) and A549 human non-small cell lung adenocarcinoma cells (LC(50)>100 uM). Moderately stimulates insulin release from rat clonal beta-cells and mouse pancreatic islets