Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) involved in glycolysis and gluconeogenesis. Catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate. The contribution of the TDH1, TDH2, and TDH3 to the total glyceraldehyde-3-phosphate dehydrogenase activity is 10-15, 25-30, and 50-60%, respectively. May be involved in a process other than glycolysis because it is synthesized by cells in stationary phase