Transcription regulator. Plays a role in erythropoiesis, binding to promoters and activating transcription of embryonic alpha globin e1 hbae1.1 and microRNA mir-144, in erythroid progenitors; perhaps acting as part of a negative feedback loop with mir-144. May coordinate repression of genes controlling myocardial differentiation and mitochondrial metabolism with positive modulation of cell proliferation genes. Required for regeneration of the myocardium after injury, probably acting by stimulating renewal of preexisting cardiomyocytes in adult hearts