General stress-responsive transcription factor that governs multiple stress responses and adaptations. Plays a key role in virulence. Mediates the expression of LAC1, which is the major laccase involved in melanin synthesis. Positively regulates BZP4 induction under conditions of nutrient starvation and basal expression levels of MBS1 and USV101, 3 major transcription factors that independently contribute to melanin production. Acts also as a key regulator of ergosterol gene expression