NRPS-like oxidoreductasee; part of the fragmented gene cluster that mediates the biosynthesis of fusarochromene, a tryptophan-derived metabolite closely related to a group of mycotoxins including fusarochromanone. Within the pathway, fscA acts as an oxidoreductase that reduces the carboxyl group of 4-hydroxykyrunenine to primary alcohol (Probable). The first step of the pathway is the epimerization of L-tryptophan to D-tryptophan in the presence of the NRPS-like tryptophan epimerase fscC. D-tryptophan is subsequently hydroxylated by the tryptophan 6-hydroxylase fscE to yield 6-hydroxytryptophan. The pyrrole ring undergoes cleavaged by the tryptophan 2,3-dioxygenase fscD and is finally converted to 4-hydroxykyrunenine by the hydrolase fscH. The NRPS-like oxidoreductase fscA reduces the carboxyl group to primary alcohol and the DMATS-type prenyltransferase fscG performs prenylation, followed by the formation of a chromene ring catalyzed by the oxidoreductase fscI, which leads to desacetylfusarochromene. Epoxidation by fscF and rearrangement reactions of chromene double bonds convert compound desacetylfusarochromene to fusarochromanones. Although specific acetyltransferases were not found near the fsc gene cluster, several predicted enzymes containing the N-acetyltransferase superfamily domain are present in the genome of F.equiseti. These predicted enzymes may have the potential to convert desacetylfusarochromene to fusarochromene (Probable)