1990年至1999年間，澳門嘅博物館發展進入黃金時期，喺呢十年入邊新開設咗10間博物館，遠超1990年代之前嘅總數，當中除咗一間係私營博物館（澳門林則徐紀念館）之外，其他都係由唔同嘅政府部門營運，而且當中有近一半係喺澳門文物名錄所指定嘅建築物改建而成（例如聖物寶庫、消防博物館等等）。2000年代初，澳門嘅博物館數目仍然不斷增加，主要係私營博物館，新開設數量試過比公營新開設嘅多。2004年，由政府改建舊當鋪「德成按」而成嘅典當業展示館榮獲聯合國教科文組織亞太區文物古蹟保護將，係澳門首次有博物館獲得國際獎項。自從2006年通訊博物館同路氹歷史館啟用之後，博物館嘅發展速度先稍為減緩，直至2010年先有新館開放——澳門科學館。
Between 1990 and 1999, Macao's museum development entered a golden age, with 10 new museums opened in this decade, far more than the total number before the 1990s, of which all but one was a private museum (Lin Zexu Memorial Museum of Macau), the others were operated by different government departments, and nearly half of them were converted into buildings designated by the Macao Heritage List (e.g. Relic Treasury, Fire Museum, etc.). In the early 2000s, the number of museums in Macao was still increasing, mainly in the private sector, and the number of new openings used to be higher than that of the public sector. In 2004, the Pawnshop Exhibition Centre, which was renovated by the government from an old pawnshop "Tak Shing Press", was awarded the UNESCO Asia-Pacific Heritage Conservation Programme, marking the first time that a museum in Macao has won an international award. Since the opening of the Communications Museum and the Cotai History Museum in 2006, the development of the museum has slowed down slightly until 2010, when a new museum, the Macao Science Center, was opened.