顧定軒讀過仁濟醫院羅陳楚思中學，響中學時期開始參與模特兒工作。畢業後開始接拍唔同短片同電影，佢亦演出過唔少電視劇，如《大眾情性》和《獅子山下2015－高價收購》等，亦曾演出電影，包括《愛·尋·迷》同《藍天白雲》。
Gu Dingxuan studied at Renji Hospital's Lo Chan Chu Si Secondary School and began to work as a model in middle school. After graduating, he began to shoot various short films and films, and he has also acted in many TV dramas, such as "Mass Sex" and "Under the Lion Rock 2015 - High Price Acquisition", as well as films such as "Love· Seeking · Fans" and "Blue Sky and White Clouds".