  The first law of thermodynamics, which governs energy conservation, is traditionally formulated as an equality. Surprisingly, we demonstrate that the first law alone implies a universal Landauer-like inequality linking changes in system entropy and energy. However, contrasting with the Landauer principle derived from the second law of thermodynamics, our obtained Landauer-like inequality solely relies on system information and is applicable in scenarios where implementing the Landauer principle becomes challenging. Furthermore, the Landauer-like inequality can complement the Landauer principle by establishing a dual {\it upper} bound on heat dissipation. We illustrate the practical utility of the Landauer-like inequality in dissipative quantum state preparation and quantum information erasure applications. Our findings offer new insights into identifying thermodynamic constraints relevant to the fields of quantum thermodynamics and the energetics of quantum information processing and more specifically, this approach could facilitate investigations into systems coupled to non-thermal baths or scenarios where access to bath information is limited. 
Universal Landauer-Like Inequality from the First Law of Thermodynamics